SELEX—A (r)evolutionary method to generate high-affinity nucleic acid ligands
he SELEX method was modified over the years in different ways to become more efficient and less time consuming, to reach higher affinities of the aptamers ...
http://www.sciencedirect.com/science?_ob=ArticleURL&_udi=B6VRM-4P06CP3-1&_user=10&_rdoc=1&_fmt=&_orig=search&_sort=d&view=c&_acct=C000
TRUNCATION SELEX METHOD
A method for identifying nucleic acid ligands of a target molecule from a candidate mixture comprised of single stranded nucleic acids each having a region ...
www.wipo.int/pctdb/en/wo.jsp?IA=US2000007486&DISPLAY=CLAIMS
SELEX: In vitro selections: Evolution in a tube
B) Schematic of the SELEX protocol. In practice there are two important considerations for making SELEX work. First you have to be able to distinguish the ...
http://mmi.missouri.edu/burke/db2.php
HTPSELEX--a database of high-throughput SELEX libraries.
Jan 1, 2006 ... On the DNA side, the SELEX protocol uses a library of synthetic oligonucleotides consisting of a random internal part and constant flanking ...
nar.oxfordjournals.org/cgi/content/full/34/suppl_1/D90
SELEX experiments: new prospects, applications and data analysis in Inferring Regulatory Pathways.
new modifications of the SELEX protocol have been proposed. In particular, a ..... Consequently, we will further call the standard SELEX protocol high ...
www.mbi.osu.edu/publications/techreports/techreport_63.pdf
Development of an automated in vitro selection protocol to obtain RNA-based aptamers: identification of a biostable substance P antagonist.
We have developed an automated SELEX (Systematic Evolution of Ligands by EXponential Enrichment) process that allows the execution of in vitro selection ...
nar.oxfordjournals.org/cgi/content/abstract/33/4/e45
Determination of Nucleic Acid Recognition Sequences by SELEX
Over the last 10 yr, the SELEX procedure (systematic evolution of ... The method was first described for the identification of the DNA and RNA target ...
http://www.springerprotocols.com/Abstract/doi/10.1385/1-59259-208-2:603