AFF4 rabbit pAb - 50 μL

The protein encoded by this gene belongs to the AF4 family of transcription factors involved in leukemia. It is a component of the positive transcription elongation factor b (P-TEFb) complex. A chromosomal translocation involving this gene and MLL gene on chromosome 11 is found in infant acute lymphoblastic leukemia with ins (5;11) (q31;q31q23). [provided by RefSeq, Oct 2011],