Volume : 50 µL
Clone Number :
Aliases : EXTL1 antibody; EXTL antibody; Exostosin-like 1 antibody; EC 2.4.1.224 antibody; Exostosin-L antibody; Glucuronosyl-N-acetylglucosaminyl-proteoglycan 4-alpha-N-acetylglucosaminyltransferase antibody; M µLtiple exostosis-like protein antibody
Product Type : polyclonal Ab Antibody
Immunogen Species : Homo sapiens (Human)
UniProt ID : Q92935
Immunogen : Synthetic peptide of Human EXTL1
Raised in : Rabbit
Species Reactivity : Human, Mouse
Tested Applications : ELISA, IHC; ELISA : 1 : 1000-1 : 2000, IHC : 1 : 25-1 : 100
Background : This gene is a member of the m µLtiple exostoses (EXT) family of glycosyltransferases, which function in the chain polymerization of heparan s µLfate and heparin. The encoded protein harbors alpha 14- N-acetylglucosaminyltransferase activity, and is involved in chain elongation of heparan s µLfate and possibly heparin.
Clonality : polyclonal Ab
Isotype : IgG
Purification Method : Antigen affinity purification
Conj µgate : Non-conj µgated
Buffer : -20°C, pH7.4 PBS, 0.05% NaN3, 40% Glycerol
Form : Liquid
Stroage : Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
Target Names : EXTL1
Research Areas : Developmental biology;Metabolism;Signal transduction

Volume : 50 µg
Clone Number :
Aliases : Exostoses (m µLtiple) 2 antibody; Exostosin 2 antibody; Exostosin-2 antibody; EXT2 antibody; EXT2_HUMAN antibody; Glucuronosyl N acetylglucosaminyl proteoglycan 4 alpha N acetylglucosaminyltransferase antibody; Glucuronosyl-N-acetylglucosaminyl-proteoglycan/N-acetylglucosaminyl-proteoglycan 4-alpha-N-acetylglucosaminyltransferase antibody; M µLtiple exostoses protein 2 antibody; N acetylglucosaminyl proteoglycan 4 beta glucuronosyltransferase antibody; Putative tumor suppressor protein EXT2 antibody; SOTV antibody
Product Type : polyclonal Ab Antibody
Immunogen Species : Homo sapiens (Human)
UniProt ID : Q93063
Immunogen : Recombinant Human Exostosin-2 protein (180-267AA)
Raised in : Rabbit
Species Reactivity : Human
Tested Applications : ELISA
Background : Glycosyltransferase required for the biosynthesis of heparan-s µLfate. The EXT1/EXT2 complex possesses substantially higher glycosyltransferase activity than EXT1 or EXT2 alone. Appears to be a tumor suppressor. Required for the exosomal release of SDCBP, CD63 and syndecan (PubMed : 22660413).
Clonality : polyclonal Ab
Isotype : IgG
Purification Method : >95%, Protein G purified
Conj µgate : HRP
Buffer : Preservative : 0.03% Proclin 300
Constituents : 50% Glycerol, 0.01M PBS, pH 7.4
Form : Liquid
Stroage : Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
Target Names : EXT2
Research Areas : Signal transduction

Volume : 50 µg
Clone Number :
Aliases : Exostoses (m µLtiple) 2 antibody; Exostosin 2 antibody; Exostosin-2 antibody; EXT2 antibody; EXT2_HUMAN antibody; Glucuronosyl N acetylglucosaminyl proteoglycan 4 alpha N acetylglucosaminyltransferase antibody; Glucuronosyl-N-acetylglucosaminyl-proteoglycan/N-acetylglucosaminyl-proteoglycan 4-alpha-N-acetylglucosaminyltransferase antibody; M µLtiple exostoses protein 2 antibody; N acetylglucosaminyl proteoglycan 4 beta glucuronosyltransferase antibody; Putative tumor suppressor protein EXT2 antibody; SOTV antibody
Product Type : polyclonal Ab Antibody
Immunogen Species : Homo sapiens (Human)
UniProt ID : Q93063
Immunogen : Recombinant Human Exostosin-2 protein (180-267AA)
Raised in : Rabbit
Species Reactivity : Human
Tested Applications :
Background : Glycosyltransferase required for the biosynthesis of heparan-s µLfate. The EXT1/EXT2 complex possesses substantially higher glycosyltransferase activity than EXT1 or EXT2 alone. Appears to be a tumor suppressor. Required for the exosomal release of SDCBP, CD63 and syndecan (PubMed : 22660413).
Clonality : polyclonal Ab
Isotype : IgG
Purification Method : >95%, Protein G purified
Conj µgate : FITC
Buffer : Preservative : 0.03% Proclin 300
Constituents : 50% Glycerol, 0.01M PBS, pH 7.4
Form : Liquid
Stroage : Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
Target Names : EXT2
Research Areas : Signal transduction

Volume : 50 µg
Clone Number :
Aliases : Exostoses (m µLtiple) 2 antibody; Exostosin 2 antibody; Exostosin-2 antibody; EXT2 antibody; EXT2_HUMAN antibody; Glucuronosyl N acetylglucosaminyl proteoglycan 4 alpha N acetylglucosaminyltransferase antibody; Glucuronosyl-N-acetylglucosaminyl-proteoglycan/N-acetylglucosaminyl-proteoglycan 4-alpha-N-acetylglucosaminyltransferase antibody; M µLtiple exostoses protein 2 antibody; N acetylglucosaminyl proteoglycan 4 beta glucuronosyltransferase antibody; Putative tumor suppressor protein EXT2 antibody; SOTV antibody
Product Type : polyclonal Ab Antibody
Immunogen Species : Homo sapiens (Human)
UniProt ID : Q93063
Immunogen : Recombinant Human Exostosin-2 protein (180-267AA)
Raised in : Rabbit
Species Reactivity : Human
Tested Applications : ELISA
Background : Glycosyltransferase required for the biosynthesis of heparan-s µLfate. The EXT1/EXT2 complex possesses substantially higher glycosyltransferase activity than EXT1 or EXT2 alone. Appears to be a tumor suppressor. Required for the exosomal release of SDCBP, CD63 and syndecan (PubMed : 22660413).
Clonality : polyclonal Ab
Isotype : IgG
Purification Method : >95%, Protein G purified
Conj µgate : Biotin
Buffer : Preservative : 0.03% Proclin 300
Constituents : 50% Glycerol, 0.01M PBS, pH 7.4
Form : Liquid
Stroage : Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
Target Names : EXT2
Research Areas : Signal transduction

Volume : 100 µL
Host : Rabbit
Clonality : polyclonal Ab
Isotype : IgG
GeneName : EXT2
GeneID : 2132
Uniprot : Q93063
Specificity : EXT2 Antibody detects endogenous levels of EXT2.
Immunogen : A syntheVolumed peptide derived from human EXT2.
Storage : Rabbit IgG in phosphate buffered saline, pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol. Store at -20 °C. Stable for 12 months from date of receipt.
Reactivity : Human,Mouse
Prediction :
Application : ELISA(peptide)
Dilution : ELISA(peptide) 1 : 20000-1 : 40000
Conj µgate : Unconj µgated
RRID :
An Introduction to Blocking Peptides : A superior strategy for validation of antibody binding is the use of blocking peptides. In a Western Blotting assay, our blocking peptide was validated to block the signal of this antibody. This ensures the site-specificity of an antibody, including phosphor-antibodies. In the case of the phosphor- antibodies, the antibodies can and will only recognize the phosphorylated target protein at the corresponding site, not the non-phosphorylated target protein or target protein phosphorylated at a different site.
Cat# Blocking Peptide : DF14915-BP
Des# Blocking Peptide : EXT2 Blocking peptide
Blocking Peptide Price : $549 CAD

Volume : 50 µg
Clone Number :
Aliases : 4-alpha-N-acetylglucosaminyltransferase antibody; exostoses (m µLtiple) 1 antibody; Exostosin 1 antibody; Exostosin glycosyltransferase 1 antibody; Exostosin-1 antibody; EXT antibody; EXT1 antibody; EXT1_HUMAN antibody; Glucuronosyl-N-acetylglucosaminyl-proteoglycan/N-acetylglucosaminyl-proteoglycan 4-alpha-N-acetylglucosaminyltransferase antibody; glucuronosyl-N-acetylglucosaminyl-proteoglycan/N-acetylglucosaminyl-proteoglycan antibody; Langer-Giedion syndrome chromosome region antibody; LGCR antibody; LGS antibody; M µLtiple exostoses protein 1 antibody; M µLtiple exostoses protein 1 homolog antibody; N-acetylglucosaminyl-proteoglycan 4-beta-glucuronosyltransferase antibody; Putative tumor suppressor protein EXT1 antibody; TRPS2 antibody; TTV antibody
Product Type : polyclonal Ab Antibody
Immunogen Species : Homo sapiens (Human)
UniProt ID : Q16394
Immunogen : Recombinant Human Exostosin-1 protein (28-171AA)
Raised in : Rabbit
Species Reactivity : Human
Tested Applications : ELISA
Background : Glycosyltransferase required for the biosynthesis of heparan-s µLfate. The EXT1/EXT2 complex possesses substantially higher glycosyltransferase activity than EXT1 or EXT2 alone. Appears to be a tumor suppressor. Required for the exosomal release of SDCBP, CD63 and syndecan (PubMed : 22660413).
Clonality : polyclonal Ab
Isotype : IgG
Purification Method : >95%, Protein G purified
Conj µgate : HRP
Buffer : Preservative : 0.03% Proclin 300
Constituents : 50% Glycerol, 0.01M PBS, PH 7.4
Form : Liquid
Stroage : Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
Target Names : EXT1
Research Areas : Signal transduction

Volume : 50 µg
Clone Number :
Aliases : 4-alpha-N-acetylglucosaminyltransferase antibody; exostoses (m µLtiple) 1 antibody; Exostosin 1 antibody; Exostosin glycosyltransferase 1 antibody; Exostosin-1 antibody; EXT antibody; EXT1 antibody; EXT1_HUMAN antibody; Glucuronosyl-N-acetylglucosaminyl-proteoglycan/N-acetylglucosaminyl-proteoglycan 4-alpha-N-acetylglucosaminyltransferase antibody; glucuronosyl-N-acetylglucosaminyl-proteoglycan/N-acetylglucosaminyl-proteoglycan antibody; Langer-Giedion syndrome chromosome region antibody; LGCR antibody; LGS antibody; M µLtiple exostoses protein 1 antibody; M µLtiple exostoses protein 1 homolog antibody; N-acetylglucosaminyl-proteoglycan 4-beta-glucuronosyltransferase antibody; Putative tumor suppressor protein EXT1 antibody; TRPS2 antibody; TTV antibody
Product Type : polyclonal Ab Antibody
Immunogen Species : Homo sapiens (Human)
UniProt ID : Q16394
Immunogen : Recombinant Human Exostosin-1 protein (28-171AA)
Raised in : Rabbit
Species Reactivity : Human
Tested Applications :
Background : Glycosyltransferase required for the biosynthesis of heparan-s µLfate. The EXT1/EXT2 complex possesses substantially higher glycosyltransferase activity than EXT1 or EXT2 alone. Appears to be a tumor suppressor. Required for the exosomal release of SDCBP, CD63 and syndecan (PubMed : 22660413).
Clonality : polyclonal Ab
Isotype : IgG
Purification Method : >95%, Protein G purified
Conj µgate : FITC
Buffer : Preservative : 0.03% Proclin 300
Constituents : 50% Glycerol, 0.01M PBS, PH 7.4
Form : Liquid
Stroage : Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
Target Names : EXT1
Research Areas : Signal transduction

Volume : 50 µg
Clone Number :
Aliases : 4-alpha-N-acetylglucosaminyltransferase antibody; exostoses (m µLtiple) 1 antibody; Exostosin 1 antibody; Exostosin glycosyltransferase 1 antibody; Exostosin-1 antibody; EXT antibody; EXT1 antibody; EXT1_HUMAN antibody; Glucuronosyl-N-acetylglucosaminyl-proteoglycan/N-acetylglucosaminyl-proteoglycan 4-alpha-N-acetylglucosaminyltransferase antibody; glucuronosyl-N-acetylglucosaminyl-proteoglycan/N-acetylglucosaminyl-proteoglycan antibody; Langer-Giedion syndrome chromosome region antibody; LGCR antibody; LGS antibody; M µLtiple exostoses protein 1 antibody; M µLtiple exostoses protein 1 homolog antibody; N-acetylglucosaminyl-proteoglycan 4-beta-glucuronosyltransferase antibody; Putative tumor suppressor protein EXT1 antibody; TRPS2 antibody; TTV antibody
Product Type : polyclonal Ab Antibody
Immunogen Species : Homo sapiens (Human)
UniProt ID : Q16394
Immunogen : Recombinant Human Exostosin-1 protein (28-171AA)
Raised in : Rabbit
Species Reactivity : Human
Tested Applications : ELISA
Background : Glycosyltransferase required for the biosynthesis of heparan-s µLfate. The EXT1/EXT2 complex possesses substantially higher glycosyltransferase activity than EXT1 or EXT2 alone. Appears to be a tumor suppressor. Required for the exosomal release of SDCBP, CD63 and syndecan (PubMed : 22660413).
Clonality : polyclonal Ab
Isotype : IgG
Purification Method : >95%, Protein G purified
Conj µgate : Biotin
Buffer : Preservative : 0.03% Proclin 300
Constituents : 50% Glycerol, 0.01M PBS, PH 7.4
Form : Liquid
Stroage : Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
Target Names : EXT1
Research Areas : Signal transduction

Volume : 100 µL
Host : Rabbit
Clonality : polyclonal Ab
Isotype : IgG
GeneName : EXT1
GeneID : 2131
Uniprot : Q16394
Specificity : EXT1 Antibody detects endogenous levels of total EXT1.
Immunogen : A syntheVolumed peptide derived from human EXT1 corresponding to a region within N-terminal amino acids.
Storage : Rabbit IgG in phosphate buffered saline , pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol.Store at -20 °C.Stable for 12 months from date of receipt.
Reactivity : Human,Mouse,Rat
Prediction : Pig,Bovine,Horse,Sheep,Dog
Application : WB,IHC,ELISA(peptide)
Dilution : WB 1 : 500-1 : 2000, IHC 1 : 50-1 : 200, ELISA(peptide) 1 : 20000-1 : 40000
Conj µgate : Unconj µgated
RRID : AB_2838726
An Introduction to Blocking Peptides : A superior strategy for validation of antibody binding is the use of blocking peptides. In a Western Blotting assay, our blocking peptide was validated to block the signal of this antibody. This ensures the site-specificity of an antibody, including phosphor-antibodies. In the case of the phosphor- antibodies, the antibodies can and will only recognize the phosphorylated target protein at the corresponding site, not the non-phosphorylated target protein or target protein phosphorylated at a different site.
Cat# Blocking Peptide : DF6764-BP
Des# Blocking Peptide : EXT1 Blocking peptide
Blocking Peptide Price : $549 CAD

Volume : 100 µL
Host : Rabbit
Clonality : polyclonal Ab
Isotype : IgG
GeneName : XPO5
GeneID : 57510
Uniprot : Q9HAV4
Specificity : Exportin-5 Antibody detects endogenous levels of total Exportin-5.
Immunogen : A syntheVolumed peptide derived from human Exportin-5, corresponding to a region within the internal amino acids.
Storage : Rabbit IgG in phosphate buffered saline , pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol.Store at -20 °C.Stable for 12 months from date of receipt.
Reactivity : Human,Mouse,Rat
Prediction : Pig,Bovine,Horse,Sheep,Rabbit,Dog,Chicken
Application : WB,IHC,IF/ICC,ELISA(peptide)
Dilution : WB 1 : 500-1 : 2000, IF/ICC 1 : 100-1 : 500, IHC 1 : 50-1 : 200, ELISA(peptide) 1 : 20000-1 : 40000
Conj µgate : Unconj µgated
RRID : AB_2846435
An Introduction to Blocking Peptides : A superior strategy for validation of antibody binding is the use of blocking peptides. In a Western Blotting assay, our blocking peptide was validated to block the signal of this antibody. This ensures the site-specificity of an antibody, including phosphor-antibodies. In the case of the phosphor- antibodies, the antibodies can and will only recognize the phosphorylated target protein at the corresponding site, not the non-phosphorylated target protein or target protein phosphorylated at a different site.
Cat# Blocking Peptide : DF13416-BP
Des# Blocking Peptide : Exportin-5 Blocking peptide
Blocking Peptide Price : $549 CAD

Volume : 100 µL
Host : Rabbit
Clonality : polyclonal Ab
Isotype : IgG
GeneName : XPOT
GeneID : 11260
Uniprot : O43592
Specificity : Exportin T Antibody detects endogenous levels of total Exportin T.
Immunogen : A syntheVolumed peptide derived from Human MYOCD.
Storage : Rabbit IgG in phosphate buffered saline , pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol.Store at -20 °C.Stable for 12 months from date of receipt.
Reactivity : Human,Mouse,Rat
Prediction :
Application : ELISA(peptide)
Dilution : ELISA(peptide) 1 : 20000-1 : 40000
Conj µgate : Unconj µgated
RRID :
An Introduction to Blocking Peptides : A superior strategy for validation of antibody binding is the use of blocking peptides. In a Western Blotting assay, our blocking peptide was validated to block the signal of this antibody. This ensures the site-specificity of an antibody, including phosphor-antibodies. In the case of the phosphor- antibodies, the antibodies can and will only recognize the phosphorylated target protein at the corresponding site, not the non-phosphorylated target protein or target protein phosphorylated at a different site.
Cat# Blocking Peptide : DF13834-BP
Des# Blocking Peptide : Exportin T Blocking peptide
Blocking Peptide Price : $549 CAD

Volume : 50 µg
Clone Number :
Aliases : EXPH5 antibody; KIAA0624 antibody; SLAC2BExophilin-5 antibody; Synaptotagmin-like protein homolog lacking C2 domains b antibody; SlaC2-b antibody; Slp homolog lacking C2 domains b antibody
Product Type : polyclonal Ab Antibody
Immunogen Species : Homo sapiens (Human)
UniProt ID : Q8NEV8
Immunogen : Recombinant Human Exophilin-5 protein (1235-1490AA)
Raised in : Rabbit
Species Reactivity : Human
Tested Applications : ELISA
Background : May act as Rab effector protein and play a role in vesicle trafficking.
Clonality : polyclonal Ab
Isotype : IgG
Purification Method : >95%, Protein G purified
Conj µgate : HRP
Buffer : Preservative : 0.03% Proclin 300
Constituents : 50% Glycerol, 0.01M PBS, PH 7.4
Form : Liquid
Stroage : Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
Target Names : EXPH5
Research Areas : Signal transduction

Volume : 50 µg
Clone Number :
Aliases : EXPH5 antibody; KIAA0624 antibody; SLAC2BExophilin-5 antibody; Synaptotagmin-like protein homolog lacking C2 domains b antibody; SlaC2-b antibody; Slp homolog lacking C2 domains b antibody
Product Type : polyclonal Ab Antibody
Immunogen Species : Homo sapiens (Human)
UniProt ID : Q8NEV8
Immunogen : Recombinant Human Exophilin-5 protein (1235-1490AA)
Raised in : Rabbit
Species Reactivity : Human
Tested Applications :
Background : May act as Rab effector protein and play a role in vesicle trafficking.
Clonality : polyclonal Ab
Isotype : IgG
Purification Method : >95%, Protein G purified
Conj µgate : FITC
Buffer : Preservative : 0.03% Proclin 300
Constituents : 50% Glycerol, 0.01M PBS, PH 7.4
Form : Liquid
Stroage : Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
Target Names : EXPH5
Research Areas : Signal transduction

Volume : 50 µg
Clone Number :
Aliases : EXPH5 antibody; KIAA0624 antibody; SLAC2BExophilin-5 antibody; Synaptotagmin-like protein homolog lacking C2 domains b antibody; SlaC2-b antibody; Slp homolog lacking C2 domains b antibody
Product Type : polyclonal Ab Antibody
Immunogen Species : Homo sapiens (Human)
UniProt ID : Q8NEV8
Immunogen : Recombinant Human Exophilin-5 protein (1235-1490AA)
Raised in : Rabbit
Species Reactivity : Human
Tested Applications : ELISA
Background : May act as Rab effector protein and play a role in vesicle trafficking.
Clonality : polyclonal Ab
Isotype : IgG
Purification Method : >95%, Protein G purified
Conj µgate : Biotin
Buffer : Preservative : 0.03% Proclin 300
Constituents : 50% Glycerol, 0.01M PBS, PH 7.4
Form : Liquid
Stroage : Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
Target Names : EXPH5
Research Areas : Signal transduction

Volume : 100 µL
Host : Rabbit
Clonality : polyclonal Ab
Isotype : IgG
GeneName : EXPH5
GeneID : 23086
Uniprot : Q8NEV8
Specificity : EXPH5 Antibody detects endogenous levels of total EXPH5.
Immunogen : A syntheVolumed peptide derived from human EXPH5, corresponding to a region within C-terminal amino acids.
Storage : Rabbit IgG in phosphate buffered saline , pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol.Store at -20 °C.Stable for 12 months from date of receipt.
Reactivity : Human
Prediction :
Application : WB
Dilution : WB 1 : 500-1 : 2000
Conj µgate : Unconj µgated
RRID : AB_2845953
An Introduction to Blocking Peptides : A superior strategy for validation of antibody binding is the use of blocking peptides. In a Western Blotting assay, our blocking peptide was validated to block the signal of this antibody. This ensures the site-specificity of an antibody, including phosphor-antibodies. In the case of the phosphor- antibodies, the antibodies can and will only recognize the phosphorylated target protein at the corresponding site, not the non-phosphorylated target protein or target protein phosphorylated at a different site.
Cat# Blocking Peptide : DF12992-BP
Des# Blocking Peptide : EXPH5 Blocking peptide
Blocking Peptide Price : $549 CAD

Volume : 50 µg
Protein Type : Other proteins
Product Grade : For Research Use.
Tag : N-6His
Species : Mouse
Expressed In : Human Cells
Note : Usually in stock. Smaller quantities and volume discounts are available. For further information, please contact us.

Volume : 100 µL
Host : Rabbit
Clonality : polyclonal Ab
Isotype : IgG
GeneName : EXOSC9
GeneID : 5393
Uniprot : Q06265
Specificity : EXOSC9 Antibody detects endogenous levels of EXOSC9.
Immunogen : A syntheVolumed peptide derived from human EXOSC9.
Storage : Rabbit IgG in phosphate buffered saline, pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol. Store at -20 °C. Stable for 12 months from date of receipt.
Reactivity : Human,Mouse,Rat
Prediction :
Application : ELISA(peptide)
Dilution : ELISA(peptide) 1 : 20000-1 : 40000
Conj µgate : Unconj µgated
RRID :
An Introduction to Blocking Peptides : A superior strategy for validation of antibody binding is the use of blocking peptides. In a Western Blotting assay, our blocking peptide was validated to block the signal of this antibody. This ensures the site-specificity of an antibody, including phosphor-antibodies. In the case of the phosphor- antibodies, the antibodies can and will only recognize the phosphorylated target protein at the corresponding site, not the non-phosphorylated target protein or target protein phosphorylated at a different site.
Cat# Blocking Peptide : DF15372-BP
Des# Blocking Peptide : EXOSC9 Blocking peptide
Blocking Peptide Price : $549 CAD

Volume : 50 µg
Clone Number :
Aliases : bA421P11.3 antibody; CBP interacting protein 3 antibody; CIP3 antibody; EAP2 antibody; EC 3.1.13 antibody; EXOS8_HUMAN antibody; EXOSC8 antibody; Exosome complex component RRP43 antibody; Exosome complex exonuclease RRP43 antibody; Exosome component 8 antibody; OIP-2 antibody; OIP2 antibody; Opa interacting protein 2 antibody; Opa-interacting protein 2 antibody; OTTHUMP00000042274 antibody; p9 antibody; Ribosomal RNA processing protein 43 antibody; Ribosomal RNA processing protein 43; S. cerevisiae; homolog of antibody; Ribosomal RNA-processing protein 43 antibody; RP11 421P11.3 antibody; RRP43 antibody; Rrp43p antibody
Product Type : polyclonal Ab Antibody
Immunogen Species : Homo sapiens (Human)
UniProt ID : Q96B26
Immunogen : Recombinant Human Exosome complex component RRP43 protein (2-276AA)
Raised in : Rabbit
Species Reactivity : Human
Tested Applications : ELISA
Background : Non-catalytic component of the RNA exosome complex which has 3\'->5\' exoribonuclease activity and participates in a m µLtitude of cell µLar RNA processing and degradation events. In the nucleus, the RNA exosome complex is involved in proper maturation of stable RNA species such as rRNA, snRNA and snoRNA, in the elimination of RNA processing by-products and non-coding \'pervasive\' transcripts, such as antisense RNA species and promoter-upstream transcripts (PROMPTs), and of mRNAs with processing defects, thereby limiting or excluding their export to the cytoplasm. The RNA exosome may be involved in Ig class switch recombination (CSR) and/or Ig variable region somatic hypermutation (SHM) by targeting AICDA deamination activity to transcribed dsDNA substrates. In the cytoplasm, the RNA exosome complex is involved in general mRNA turnover and specifically degrades inherently unstable mRNAs containing AU-rich elements (AREs) within their 3\' untranslated regions, and in RNA surveillance pathways, preventing translation of aberrant mRNAs. It seems to be involved in degradation of histone mRNA. The catalytic inactive RNA exosome core complex of 9 subunits (Exo-9) is proposed to play a pivotal role in the binding and presentation of RNA for ribonucleolysis, and to serve as a scaffold for the association with catalytic subunits and accessory proteins or complexes. EXOSC8 binds to ARE-containing RNAs.
Clonality : polyclonal Ab
Isotype : IgG
Purification Method : >95%, Protein G purified
Conj µgate : HRP
Buffer : Preservative : 0.03% Proclin 300
Constituents : 50% Glycerol, 0.01M PBS, PH 7.4
Form : Liquid
Stroage : Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
Target Names : EXOSC8
Research Areas : Epigenetics and Nuclear Signaling

Volume : 50 µg
Clone Number :
Aliases : bA421P11.3 antibody; CBP interacting protein 3 antibody; CIP3 antibody; EAP2 antibody; EC 3.1.13 antibody; EXOS8_HUMAN antibody; EXOSC8 antibody; Exosome complex component RRP43 antibody; Exosome complex exonuclease RRP43 antibody; Exosome component 8 antibody; OIP-2 antibody; OIP2 antibody; Opa interacting protein 2 antibody; Opa-interacting protein 2 antibody; OTTHUMP00000042274 antibody; p9 antibody; Ribosomal RNA processing protein 43 antibody; Ribosomal RNA processing protein 43; S. cerevisiae; homolog of antibody; Ribosomal RNA-processing protein 43 antibody; RP11 421P11.3 antibody; RRP43 antibody; Rrp43p antibody
Product Type : polyclonal Ab Antibody
Immunogen Species : Homo sapiens (Human)
UniProt ID : Q96B26
Immunogen : Recombinant Human Exosome complex component RRP43 protein (2-276AA)
Raised in : Rabbit
Species Reactivity : Human
Tested Applications :
Background : Non-catalytic component of the RNA exosome complex which has 3\'->5\' exoribonuclease activity and participates in a m µLtitude of cell µLar RNA processing and degradation events. In the nucleus, the RNA exosome complex is involved in proper maturation of stable RNA species such as rRNA, snRNA and snoRNA, in the elimination of RNA processing by-products and non-coding \'pervasive\' transcripts, such as antisense RNA species and promoter-upstream transcripts (PROMPTs), and of mRNAs with processing defects, thereby limiting or excluding their export to the cytoplasm. The RNA exosome may be involved in Ig class switch recombination (CSR) and/or Ig variable region somatic hypermutation (SHM) by targeting AICDA deamination activity to transcribed dsDNA substrates. In the cytoplasm, the RNA exosome complex is involved in general mRNA turnover and specifically degrades inherently unstable mRNAs containing AU-rich elements (AREs) within their 3\' untranslated regions, and in RNA surveillance pathways, preventing translation of aberrant mRNAs. It seems to be involved in degradation of histone mRNA. The catalytic inactive RNA exosome core complex of 9 subunits (Exo-9) is proposed to play a pivotal role in the binding and presentation of RNA for ribonucleolysis, and to serve as a scaffold for the association with catalytic subunits and accessory proteins or complexes. EXOSC8 binds to ARE-containing RNAs.
Clonality : polyclonal Ab
Isotype : IgG
Purification Method : >95%, Protein G purified
Conj µgate : FITC
Buffer : Preservative : 0.03% Proclin 300
Constituents : 50% Glycerol, 0.01M PBS, PH 7.4
Form : Liquid
Stroage : Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
Target Names : EXOSC8
Research Areas : Epigenetics and Nuclear Signaling

Volume : 50 µg
Clone Number :
Aliases : bA421P11.3 antibody; CBP interacting protein 3 antibody; CIP3 antibody; EAP2 antibody; EC 3.1.13 antibody; EXOS8_HUMAN antibody; EXOSC8 antibody; Exosome complex component RRP43 antibody; Exosome complex exonuclease RRP43 antibody; Exosome component 8 antibody; OIP-2 antibody; OIP2 antibody; Opa interacting protein 2 antibody; Opa-interacting protein 2 antibody; OTTHUMP00000042274 antibody; p9 antibody; Ribosomal RNA processing protein 43 antibody; Ribosomal RNA processing protein 43; S. cerevisiae; homolog of antibody; Ribosomal RNA-processing protein 43 antibody; RP11 421P11.3 antibody; RRP43 antibody; Rrp43p antibody
Product Type : polyclonal Ab Antibody
Immunogen Species : Homo sapiens (Human)
UniProt ID : Q96B26
Immunogen : Recombinant Human Exosome complex component RRP43 protein (2-276AA)
Raised in : Rabbit
Species Reactivity : Human
Tested Applications : ELISA
Background : Non-catalytic component of the RNA exosome complex which has 3\'->5\' exoribonuclease activity and participates in a m µLtitude of cell µLar RNA processing and degradation events. In the nucleus, the RNA exosome complex is involved in proper maturation of stable RNA species such as rRNA, snRNA and snoRNA, in the elimination of RNA processing by-products and non-coding \'pervasive\' transcripts, such as antisense RNA species and promoter-upstream transcripts (PROMPTs), and of mRNAs with processing defects, thereby limiting or excluding their export to the cytoplasm. The RNA exosome may be involved in Ig class switch recombination (CSR) and/or Ig variable region somatic hypermutation (SHM) by targeting AICDA deamination activity to transcribed dsDNA substrates. In the cytoplasm, the RNA exosome complex is involved in general mRNA turnover and specifically degrades inherently unstable mRNAs containing AU-rich elements (AREs) within their 3\' untranslated regions, and in RNA surveillance pathways, preventing translation of aberrant mRNAs. It seems to be involved in degradation of histone mRNA. The catalytic inactive RNA exosome core complex of 9 subunits (Exo-9) is proposed to play a pivotal role in the binding and presentation of RNA for ribonucleolysis, and to serve as a scaffold for the association with catalytic subunits and accessory proteins or complexes. EXOSC8 binds to ARE-containing RNAs.
Clonality : polyclonal Ab
Isotype : IgG
Purification Method : >95%, Protein G purified
Conj µgate : Biotin
Buffer : Preservative : 0.03% Proclin 300
Constituents : 50% Glycerol, 0.01M PBS, PH 7.4
Form : Liquid
Stroage : Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
Target Names : EXOSC8
Research Areas : Epigenetics and Nuclear Signaling

Volume : 100 µL
Host : Rabbit
Clonality : polyclonal Ab
Isotype : IgG
GeneName : EXOSC8
GeneID : 11340
Uniprot : Q96B26
Specificity : EXOSC8 Antibody detects endogenous levels of total EXOSC8.
Immunogen : A syntheVolumed peptide derived from human EXOSC8, corresponding to a region within the internal amino acids.
Storage : Rabbit IgG in phosphate buffered saline , pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol.Store at -20 °C.Stable for 12 months from date of receipt.
Reactivity : Human,Mouse,Rat
Prediction : Pig,Zebrafish,Bovine,Horse,Sheep,Rabbit,Dog,Xenopus
Application : WB
Dilution : WB 1 : 500-1 : 2000
Conj µgate : Unconj µgated
RRID : AB_2845565
An Introduction to Blocking Peptides : A superior strategy for validation of antibody binding is the use of blocking peptides. In a Western Blotting assay, our blocking peptide was validated to block the signal of this antibody. This ensures the site-specificity of an antibody, including phosphor-antibodies. In the case of the phosphor- antibodies, the antibodies can and will only recognize the phosphorylated target protein at the corresponding site, not the non-phosphorylated target protein or target protein phosphorylated at a different site.
Cat# Blocking Peptide : DF12603-BP
Des# Blocking Peptide : EXOSC8 Blocking peptide
Blocking Peptide Price : $549 CAD

Volume : 100 µg
Purification : Immunogen affinity purified
Form : liquid
Purity : 95% as determined by SDS-PAGE
Host : Rabbit
Clonality : polyclonal Ab
Clone ID :
Isotype : IgG
Storage : PBS with 0.02% sodium azide and 50% glycerol pH 7.3,-20? for 12 months(Avoid repeated freeze / thaw cycles.)
Background : Non-catalytic component of the RNA exosome complex which has 3'->5' exoribonuclease activity and participates in a m µLtitude of cell µLar RNA processing and degradation events. In the nucleus, the RNA exosome complex is involved in proper maturation of stable RNA species such as rRNA, snRNA and snoRNA, in the elimination of RNA processing by-products and non-coding 'pervasive' transcripts, such as antisense RNA species and promoter-upstream transcripts(PROMPTs), and of mRNAs with processing defects, thereby limiting or excluding their export to the cytoplasm. The RNA exosome may be involved in Ig class switch recombination(CSR) and/or Ig variable region somatic hypermutation(SHM) by targeting AICDA deamination activity to transcribed dsDNA substrates. In the cytoplasm, the RNA exosome complex is involved in general mRNA turnover and specifically degrades inherently unstable mRNAs containing AU-rich elements(AREs) within their 3' untranslated regions, and in RNA surveillance pathways, preventing translation of aberrant mRNAs. It seems to be involved in degradation of histone mRNA. The catalytic inactive RNA exosome core complex of 9 subunits(Exo-9) is proposed to play a pivotal role in the binding and presentation of RNA for ribonucleolysis, and to serve as a scaffold for the association with catalytic subunits and accessory proteins or complexes.
Immunogen : exosome component 7
Aliases : KIAA0116, RRP42
Observed MW : 37 kDa
Uniprot ID : Q15024
Reactivity : Human
Application : ELISA, WB, IHC
Recommended dilution : WB : 1 : 500-1 : 2000; IHC : 1 : 20-1 : 200
Gene ID : 23016
Research Area : Metabolism

Volume : 100 µL
Host : Rabbit
Clonality : polyclonal Ab
Isotype : IgG
GeneName : EXOSC6
GeneID : 118460
Uniprot : Q5RKV6
Specificity : EXOSC6 Antibody detects endogenous levels of EXOSC6.
Immunogen : A syntheVolumed peptide derived from human EXOSC6.
Storage : Rabbit IgG in phosphate buffered saline, pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol. Store at -20 °C. Stable for 12 months from date of receipt.
Reactivity : Human,Mouse,Rat
Prediction :
Application : ELISA(peptide)
Dilution : ELISA(peptide) 1 : 20000-1 : 40000
Conj µgate : Unconj µgated
RRID :
An Introduction to Blocking Peptides : A superior strategy for validation of antibody binding is the use of blocking peptides. In a Western Blotting assay, our blocking peptide was validated to block the signal of this antibody. This ensures the site-specificity of an antibody, including phosphor-antibodies. In the case of the phosphor- antibodies, the antibodies can and will only recognize the phosphorylated target protein at the corresponding site, not the non-phosphorylated target protein or target protein phosphorylated at a different site.
Cat# Blocking Peptide : DF15640-BP
Des# Blocking Peptide : EXOSC6 Blocking peptide
Blocking Peptide Price : $549 CAD

Volume : 50 µg
Clone Number :
Aliases : Chronic myelogenous leukemia tumor antigen 28 antibody; CML28 antibody; EXOS5_HUMAN antibody; EXOSC 5 antibody; Exosc5 antibody; Exosome complex component rrp46 antibody; exosome complex exonuclease RRP46 antibody; Exosome component 5 antibody; exosome component Rrp46 antibody; hRrp46p antibody; p12B antibody; Ribosomal RNA processing protein 46 antibody; Ribosomal RNA processing protein 46, S. cerevisiae, homolog of antibody; Ribosomal RNA-processing protein 46 antibody; RRP41B antibody; RRP46 antibody; Rrp46p antibody
Product Type : polyclonal Ab Antibody
Immunogen Species : Homo sapiens (Human)
UniProt ID : Q9NQT4
Immunogen : Recombinant Human Exosome complex component RRP46 protein (1-235AA)
Raised in : Rabbit
Species Reactivity : Human
Tested Applications : ELISA
Background : Non-catalytic component of the RNA exosome complex which has 3\'->5\' exoribonuclease activity and participates in a m µLtitude of cell µLar RNA processing and degradation events. In the nucleus, the RNA exosome complex is involved in proper maturation of stable RNA species such as rRNA, snRNA and snoRNA, in the elimination of RNA processing by-products and non-coding \'pervasive\' transcripts, such as antisense RNA species and promoter-upstream transcripts (PROMPTs), and of mRNAs with processing defects, thereby limiting or excluding their export to the cytoplasm. The RNA exosome may be involved in Ig class switch recombination (CSR) and/or Ig variable region somatic hypermutation (SHM) by targeting AICDA deamination activity to transcribed dsDNA substrates. In the cytoplasm, the RNA exosome complex is involved in general mRNA turnover and specifically degrades inherently unstable mRNAs containing AU-rich elements (AREs) within their 3\' untranslated regions, and in RNA surveillance pathways, preventing translation of aberrant mRNAs. It seems to be involved in degradation of histone mRNA. The catalytic inactive RNA exosome core complex of 9 subunits (Exo-9) is proposed to play a pivotal role in the binding and presentation of RNA for ribonucleolysis, and to serve as a scaffold for the association with catalytic subunits and accessory proteins or complexes.
Clonality : polyclonal Ab
Isotype : IgG
Purification Method : >95%, Protein G purified
Conj µgate : HRP
Buffer : Preservative : 0.03% Proclin 300
Constituents : 50% Glycerol, 0.01M PBS, PH 7.4
Form : Liquid
Stroage : Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
Target Names : EXOSC5
Research Areas : Epigenetics and Nuclear Signaling

Volume : 50 µg
Clone Number :
Aliases : Chronic myelogenous leukemia tumor antigen 28 antibody; CML28 antibody; EXOS5_HUMAN antibody; EXOSC 5 antibody; Exosc5 antibody; Exosome complex component rrp46 antibody; exosome complex exonuclease RRP46 antibody; Exosome component 5 antibody; exosome component Rrp46 antibody; hRrp46p antibody; p12B antibody; Ribosomal RNA processing protein 46 antibody; Ribosomal RNA processing protein 46, S. cerevisiae, homolog of antibody; Ribosomal RNA-processing protein 46 antibody; RRP41B antibody; RRP46 antibody; Rrp46p antibody
Product Type : polyclonal Ab Antibody
Immunogen Species : Homo sapiens (Human)
UniProt ID : Q9NQT4
Immunogen : Recombinant Human Exosome complex component RRP46 protein (1-235AA)
Raised in : Rabbit
Species Reactivity : Human
Tested Applications :
Background : Non-catalytic component of the RNA exosome complex which has 3\'->5\' exoribonuclease activity and participates in a m µLtitude of cell µLar RNA processing and degradation events. In the nucleus, the RNA exosome complex is involved in proper maturation of stable RNA species such as rRNA, snRNA and snoRNA, in the elimination of RNA processing by-products and non-coding \'pervasive\' transcripts, such as antisense RNA species and promoter-upstream transcripts (PROMPTs), and of mRNAs with processing defects, thereby limiting or excluding their export to the cytoplasm. The RNA exosome may be involved in Ig class switch recombination (CSR) and/or Ig variable region somatic hypermutation (SHM) by targeting AICDA deamination activity to transcribed dsDNA substrates. In the cytoplasm, the RNA exosome complex is involved in general mRNA turnover and specifically degrades inherently unstable mRNAs containing AU-rich elements (AREs) within their 3\' untranslated regions, and in RNA surveillance pathways, preventing translation of aberrant mRNAs. It seems to be involved in degradation of histone mRNA. The catalytic inactive RNA exosome core complex of 9 subunits (Exo-9) is proposed to play a pivotal role in the binding and presentation of RNA for ribonucleolysis, and to serve as a scaffold for the association with catalytic subunits and accessory proteins or complexes.
Clonality : polyclonal Ab
Isotype : IgG
Purification Method : >95%, Protein G purified
Conj µgate : FITC
Buffer : Preservative : 0.03% Proclin 300
Constituents : 50% Glycerol, 0.01M PBS, PH 7.4
Form : Liquid
Stroage : Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
Target Names : EXOSC5
Research Areas : Epigenetics and Nuclear Signaling

Volume : 50 µg
Clone Number :
Aliases : Chronic myelogenous leukemia tumor antigen 28 antibody; CML28 antibody; EXOS5_HUMAN antibody; EXOSC 5 antibody; Exosc5 antibody; Exosome complex component rrp46 antibody; exosome complex exonuclease RRP46 antibody; Exosome component 5 antibody; exosome component Rrp46 antibody; hRrp46p antibody; p12B antibody; Ribosomal RNA processing protein 46 antibody; Ribosomal RNA processing protein 46, S. cerevisiae, homolog of antibody; Ribosomal RNA-processing protein 46 antibody; RRP41B antibody; RRP46 antibody; Rrp46p antibody
Product Type : polyclonal Ab Antibody
Immunogen Species : Homo sapiens (Human)
UniProt ID : Q9NQT4
Immunogen : Recombinant Human Exosome complex component RRP46 protein (1-235AA)
Raised in : Rabbit
Species Reactivity : Human
Tested Applications : ELISA
Background : Non-catalytic component of the RNA exosome complex which has 3\'->5\' exoribonuclease activity and participates in a m µLtitude of cell µLar RNA processing and degradation events. In the nucleus, the RNA exosome complex is involved in proper maturation of stable RNA species such as rRNA, snRNA and snoRNA, in the elimination of RNA processing by-products and non-coding \'pervasive\' transcripts, such as antisense RNA species and promoter-upstream transcripts (PROMPTs), and of mRNAs with processing defects, thereby limiting or excluding their export to the cytoplasm. The RNA exosome may be involved in Ig class switch recombination (CSR) and/or Ig variable region somatic hypermutation (SHM) by targeting AICDA deamination activity to transcribed dsDNA substrates. In the cytoplasm, the RNA exosome complex is involved in general mRNA turnover and specifically degrades inherently unstable mRNAs containing AU-rich elements (AREs) within their 3\' untranslated regions, and in RNA surveillance pathways, preventing translation of aberrant mRNAs. It seems to be involved in degradation of histone mRNA. The catalytic inactive RNA exosome core complex of 9 subunits (Exo-9) is proposed to play a pivotal role in the binding and presentation of RNA for ribonucleolysis, and to serve as a scaffold for the association with catalytic subunits and accessory proteins or complexes.
Clonality : polyclonal Ab
Isotype : IgG
Purification Method : >95%, Protein G purified
Conj µgate : Biotin
Buffer : Preservative : 0.03% Proclin 300
Constituents : 50% Glycerol, 0.01M PBS, PH 7.4
Form : Liquid
Stroage : Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
Target Names : EXOSC5
Research Areas : Epigenetics and Nuclear Signaling

Volume : 100 µL
Host : Rabbit
Clonality : polyclonal Ab
Isotype : IgG
GeneName : EXOSC5
GeneID : 56915
Uniprot : Q9NQT4
Specificity : EXOSC5 Antibody detects endogenous levels of total EXOSC5.
Immunogen : A syntheVolumed peptide derived from Human MYOCD.
Storage : Rabbit IgG in phosphate buffered saline , pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol.Store at -20 °C.Stable for 12 months from date of receipt.
Reactivity : Human,Mouse
Prediction :
Application : ELISA(peptide)
Dilution : ELISA(peptide) 1 : 20000-1 : 40000
Conj µgate : Unconj µgated
RRID :
An Introduction to Blocking Peptides : A superior strategy for validation of antibody binding is the use of blocking peptides. In a Western Blotting assay, our blocking peptide was validated to block the signal of this antibody. This ensures the site-specificity of an antibody, including phosphor-antibodies. In the case of the phosphor- antibodies, the antibodies can and will only recognize the phosphorylated target protein at the corresponding site, not the non-phosphorylated target protein or target protein phosphorylated at a different site.
Cat# Blocking Peptide : DF13931-BP
Des# Blocking Peptide : EXOSC5 Blocking peptide
Blocking Peptide Price : $549 CAD

Volume : 100 µL
Host : Rabbit
Clonality : polyclonal Ab
Isotype : IgG
GeneName : EXOSC4
GeneID : 54512
Uniprot : Q9NPD3
Specificity : EXOSC4 Antibody detects endogenous levels of total EXOSC4.
Immunogen : A syntheVolumed peptide derived from human EXOSC4, corresponding to a region within the internal amino acids.
Storage : Rabbit IgG in phosphate buffered saline , pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol.Store at -20 °C.Stable for 12 months from date of receipt.
Reactivity : Human,Mouse,Rat
Prediction : Pig,Zebrafish,Bovine,Horse,Sheep,Rabbit,Dog,Xenopus
Application : WB
Dilution : WB 1 : 500-1 : 2000
Conj µgate : Unconj µgated
RRID : AB_2845952
An Introduction to Blocking Peptides : A superior strategy for validation of antibody binding is the use of blocking peptides. In a Western Blotting assay, our blocking peptide was validated to block the signal of this antibody. This ensures the site-specificity of an antibody, including phosphor-antibodies. In the case of the phosphor- antibodies, the antibodies can and will only recognize the phosphorylated target protein at the corresponding site, not the non-phosphorylated target protein or target protein phosphorylated at a different site.
Cat# Blocking Peptide : DF12991-BP
Des# Blocking Peptide : EXOSC4 Blocking peptide
Blocking Peptide Price : $549 CAD

Volume : 50 µg
Clone Number :
Aliases : EXOSC3 antibody; RRP40 antibody; CGI-102Exosome complex component RRP40 antibody; Exosome component 3 antibody; Ribosomal RNA-processing protein 40 antibody; p10 antibody
Product Type : polyclonal Ab Antibody
Immunogen Species : Homo sapiens (Human)
UniProt ID : Q9NQT5
Immunogen : Recombinant Human Exosome complex component RRP40 protein (2-275AA)
Raised in : Rabbit
Species Reactivity : Human
Tested Applications : ELISA
Background : Non-catalytic component of the RNA exosome complex which has 3\'->5\' exoribonuclease activity and participates in a m µLtitude of cell µLar RNA processing and degradation events. In the nucleus, the RNA exosome complex is involved in proper maturation of stable RNA species such as rRNA, snRNA and snoRNA, in the elimination of RNA processing by-products and non-coding \'pervasive\' transcripts, such as antisense RNA species and promoter-upstream transcripts (PROMPTs), and of mRNAs with processing defects, thereby limiting or excluding their export to the cytoplasm. The RNA exosome may be involved in Ig class switch recombination (CSR) and/or Ig variable region somatic hypermutation (SHM) by targeting AICDA deamination activity to transcribed dsDNA substrates. In the cytoplasm, the RNA exosome complex is involved in general mRNA turnover and specifically degrades inherently unstable mRNAs containing AU-rich elements (AREs) within their 3\' untranslated regions, and in RNA surveillance pathways, preventing translation of aberrant mRNAs. It seems to be involved in degradation of histone mRNA. The catalytic inactive RNA exosome core complex of 9 subunits (Exo-9) is proposed to play a pivotal role in the binding and presentation of RNA for ribonucleolysis, and to serve as a scaffold for the association with catalytic subunits and accessory proteins or complexes. EXOSC3 as peripheral part of the Exo-9 complex stabilizes the hexameric ring of RNase PH-domain subunits thro µgh contacts with EXOSC9 and EXOSC5.
Clonality : polyclonal Ab
Isotype : IgG
Purification Method : >95%, Protein G purified
Conj µgate : HRP
Buffer : Preservative : 0.03% Proclin 300
Constituents : 50% Glycerol, 0.01M PBS, PH 7.4
Form : Liquid
Stroage : Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
Target Names : EXOSC3
Research Areas : Epigenetics and Nuclear Signaling

Volume : 50 µg
Clone Number :
Aliases : EXOSC3 antibody; RRP40 antibody; CGI-102Exosome complex component RRP40 antibody; Exosome component 3 antibody; Ribosomal RNA-processing protein 40 antibody; p10 antibody
Product Type : polyclonal Ab Antibody
Immunogen Species : Homo sapiens (Human)
UniProt ID : Q9NQT5
Immunogen : Recombinant Human Exosome complex component RRP40 protein (2-275AA)
Raised in : Rabbit
Species Reactivity : Human
Tested Applications :
Background : Non-catalytic component of the RNA exosome complex which has 3\'->5\' exoribonuclease activity and participates in a m µLtitude of cell µLar RNA processing and degradation events. In the nucleus, the RNA exosome complex is involved in proper maturation of stable RNA species such as rRNA, snRNA and snoRNA, in the elimination of RNA processing by-products and non-coding \'pervasive\' transcripts, such as antisense RNA species and promoter-upstream transcripts (PROMPTs), and of mRNAs with processing defects, thereby limiting or excluding their export to the cytoplasm. The RNA exosome may be involved in Ig class switch recombination (CSR) and/or Ig variable region somatic hypermutation (SHM) by targeting AICDA deamination activity to transcribed dsDNA substrates. In the cytoplasm, the RNA exosome complex is involved in general mRNA turnover and specifically degrades inherently unstable mRNAs containing AU-rich elements (AREs) within their 3\' untranslated regions, and in RNA surveillance pathways, preventing translation of aberrant mRNAs. It seems to be involved in degradation of histone mRNA. The catalytic inactive RNA exosome core complex of 9 subunits (Exo-9) is proposed to play a pivotal role in the binding and presentation of RNA for ribonucleolysis, and to serve as a scaffold for the association with catalytic subunits and accessory proteins or complexes. EXOSC3 as peripheral part of the Exo-9 complex stabilizes the hexameric ring of RNase PH-domain subunits thro µgh contacts with EXOSC9 and EXOSC5.
Clonality : polyclonal Ab
Isotype : IgG
Purification Method : >95%, Protein G purified
Conj µgate : FITC
Buffer : Preservative : 0.03% Proclin 300
Constituents : 50% Glycerol, 0.01M PBS, PH 7.4
Form : Liquid
Stroage : Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
Target Names : EXOSC3
Research Areas : Epigenetics and Nuclear Signaling

Volume : 50 µg
Clone Number :
Aliases : EXOSC3 antibody; RRP40 antibody; CGI-102Exosome complex component RRP40 antibody; Exosome component 3 antibody; Ribosomal RNA-processing protein 40 antibody; p10 antibody
Product Type : polyclonal Ab Antibody
Immunogen Species : Homo sapiens (Human)
UniProt ID : Q9NQT5
Immunogen : Recombinant Human Exosome complex component RRP40 protein (2-275AA)
Raised in : Rabbit
Species Reactivity : Human
Tested Applications : ELISA
Background : Non-catalytic component of the RNA exosome complex which has 3\'->5\' exoribonuclease activity and participates in a m µLtitude of cell µLar RNA processing and degradation events. In the nucleus, the RNA exosome complex is involved in proper maturation of stable RNA species such as rRNA, snRNA and snoRNA, in the elimination of RNA processing by-products and non-coding \'pervasive\' transcripts, such as antisense RNA species and promoter-upstream transcripts (PROMPTs), and of mRNAs with processing defects, thereby limiting or excluding their export to the cytoplasm. The RNA exosome may be involved in Ig class switch recombination (CSR) and/or Ig variable region somatic hypermutation (SHM) by targeting AICDA deamination activity to transcribed dsDNA substrates. In the cytoplasm, the RNA exosome complex is involved in general mRNA turnover and specifically degrades inherently unstable mRNAs containing AU-rich elements (AREs) within their 3\' untranslated regions, and in RNA surveillance pathways, preventing translation of aberrant mRNAs. It seems to be involved in degradation of histone mRNA. The catalytic inactive RNA exosome core complex of 9 subunits (Exo-9) is proposed to play a pivotal role in the binding and presentation of RNA for ribonucleolysis, and to serve as a scaffold for the association with catalytic subunits and accessory proteins or complexes. EXOSC3 as peripheral part of the Exo-9 complex stabilizes the hexameric ring of RNase PH-domain subunits thro µgh contacts with EXOSC9 and EXOSC5.
Clonality : polyclonal Ab
Isotype : IgG
Purification Method : >95%, Protein G purified
Conj µgate : Biotin
Buffer : Preservative : 0.03% Proclin 300
Constituents : 50% Glycerol, 0.01M PBS, PH 7.4
Form : Liquid
Stroage : Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
Target Names : EXOSC3
Research Areas : Epigenetics and Nuclear Signaling

Volume : 100 µL
Host : Rabbit
Clonality : polyclonal Ab
Isotype : IgG
GeneName : EXOSC3
GeneID : 51010
Uniprot : Q9NQT5
Specificity : EXOSC3 Antibody detects endogenous levels of total EXOSC3.
Immunogen : A syntheVolumed peptide derived from human EXOSC3, corresponding to a region within the internal amino acids.
Storage : Rabbit IgG in phosphate buffered saline , pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol.Store at -20 °C.Stable for 12 months from date of receipt.
Reactivity : Human,Mouse,Rat
Prediction : Pig,Zebrafish,Bovine,Horse,Sheep,Rabbit,Dog,Chicken
Application : WB,IHC
Dilution : WB 1 : 500-1 : 2000, IHC 1 : 50-1 : 200
Conj µgate : Unconj µgated
RRID : AB_2845076
An Introduction to Blocking Peptides : A superior strategy for validation of antibody binding is the use of blocking peptides. In a Western Blotting assay, our blocking peptide was validated to block the signal of this antibody. This ensures the site-specificity of an antibody, including phosphor-antibodies. In the case of the phosphor- antibodies, the antibodies can and will only recognize the phosphorylated target protein at the corresponding site, not the non-phosphorylated target protein or target protein phosphorylated at a different site.
Cat# Blocking Peptide : DF12271-BP
Des# Blocking Peptide : EXOSC3 Blocking peptide
Blocking Peptide Price : $549 CAD

Volume : 100 µg
Purification : Immunogen affinity purified
Form : liquid
Purity : 95% as determined by SDS-PAGE
Host : Rabbit
Clonality : polyclonal Ab
Clone ID :
Isotype : IgG
Storage : PBS with 0.02% sodium azide and 50% glycerol pH 7.3,-20? for 12 months(Avoid repeated freeze / thaw cycles.)
Background : Non-catalytic component of the RNA exosome complex which has 3'->5' exoribonuclease activity and participates in a m µLtitude of cell µLar RNA processing and degradation events. In the nucleus, the RNA exosome complex is involved in proper maturation of stable RNA species such as rRNA, snRNA and snoRNA, in the elimination of RNA processing by-products and non-coding 'pervasive' transcripts, such as antisense RNA species and promoter-upstream transcripts(PROMPTs), and of mRNAs with processing defects, thereby limiting or excluding their export to the cytoplasm. The RNA exosome may be involved in Ig class switch recombination(CSR) and/or Ig variable region somatic hypermutation(SHM) by targeting AICDA deamination activity to transcribed dsDNA substrates. In the cytoplasm, the RNA exosome complex is involved in general mRNA turnover and specifically degrades inherently unstable mRNAs containing AU-rich elements(AREs) within their 3' untranslated regions, and in RNA surveillance pathways, preventing translation of aberrant mRNAs. It seems to be involved in degradation of histone mRNA. The catalytic inactive RNA exosome core complex of 9 subunits(Exo-9) is proposed to play a pivotal role in the binding and presentation of RNA for ribonucleolysis, and to serve as a scaffold for the association with catalytic subunits and accessory proteins or complexes. EXOSC2 as peripheral part of the Exo-9 complex stabilizes the hexameric ring of RNase PH-domain subunits thro µgh contacts with EXOSC4 and EXOSC7.
Immunogen : exosome component 2
Aliases : RRP4
Observed MW : 30-33 kDa
Uniprot ID : Q13868
Reactivity : Human, Mouse, Rat
Application : ELISA, WB, IHC, IF
Recommended dilution : WB : 1 : 500-1 : 2000; IHC : 1 : 20-1 : 200; IF : 1 : 20-1 : 200
Gene ID : 23404
Research Area : Metabolism

Volume : 50 µg
Clone Number :
Aliases : Autoantigen PM/Scl 2 antibody; Exosc10 antibody; Exosome component 10 antibody; EXOSX_HUMAN antibody; P100 polymyositis scleroderma overlap syndrome associated autoantigen antibody; P100 polymyositis-scleroderma overlap syndrome-associated autoantigen antibody; p2 antibody; p3 antibody; p4 antibody; PM Scl antibody; PM/Scl 100 antibody; PM/Scl-100 antibody; PMSCL antibody; PMSCL2 antibody; Polymyositis/scleroderma autoantigen 100 kDa antibody; Polymyositis/scleroderma autoantigen 2 100 kDa antibody; Polymyositis/scleroderma autoantigen 2 antibody; RRP6 antibody; Rrp6p antibody
Product Type : polyclonal Ab Antibody
Immunogen Species : Homo sapiens (Human)
UniProt ID : Q01780
Immunogen : Recombinant Human Exosome component 10 protein (587-762AA)
Raised in : Rabbit
Species Reactivity : Human
Tested Applications : ELISA
Background : Putative catalytic component of the RNA exosome complex which has 3\'->5\' exoribonuclease activity and participates in a m µLtitude of cell µLar RNA processing and degradation events. In the nucleus, the RNA exosome complex is involved in proper maturation of stable RNA species such as rRNA, snRNA and snoRNA, in the elimination of RNA processing by-products and non-coding \'pervasive\' transcripts, such as antisense RNA species and promoter-upstream transcripts (PROMPTs), and of mRNAs with processing defects, thereby limiting or excluding their export to the cytoplasm. The RNA exosome may be involved in Ig class switch recombination (CSR) and/or Ig variable region somatic hypermutation (SHM) by targeting AICDA deamination activity to transcribed dsDNA substrates. In the cytoplasm, the RNA exosome complex is involved in general mRNA turnover and specifically degrades inherently unstable mRNAs containing AU-rich elements (AREs) within their 3\' untranslated regions, and in RNA surveillance pathways, preventing translation of aberrant mRNAs. It seems to be involved in degradation of histone mRNA. EXOSC10 has 3\'-5\' exonuclease activity (By similarity). EXOSC10 is required for nucleolar localization of C1D and probably mediates the association of SKIV2L2, C1D and MPP6 wth the RNA exosome involved in the maturation of 5.8S rRNA.
Clonality : polyclonal Ab
Isotype : IgG
Purification Method : >95%, Protein G purified
Conj µgate : HRP
Buffer : Preservative : 0.03% Proclin 300
Constituents : 50% Glycerol, 0.01M PBS, pH 7.4
Form : Liquid
Stroage : Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
Target Names : EXOSC10
Research Areas : Epigenetics and Nuclear Signaling; Immunology

Volume : 50 µg
Clone Number :
Aliases : Autoantigen PM/Scl 2 antibody; Exosc10 antibody; Exosome component 10 antibody; EXOSX_HUMAN antibody; P100 polymyositis scleroderma overlap syndrome associated autoantigen antibody; P100 polymyositis-scleroderma overlap syndrome-associated autoantigen antibody; p2 antibody; p3 antibody; p4 antibody; PM Scl antibody; PM/Scl 100 antibody; PM/Scl-100 antibody; PMSCL antibody; PMSCL2 antibody; Polymyositis/scleroderma autoantigen 100 kDa antibody; Polymyositis/scleroderma autoantigen 2 100 kDa antibody; Polymyositis/scleroderma autoantigen 2 antibody; RRP6 antibody; Rrp6p antibody
Product Type : polyclonal Ab Antibody
Immunogen Species : Homo sapiens (Human)
UniProt ID : Q01780
Immunogen : Recombinant Human Exosome component 10 protein (587-762AA)
Raised in : Rabbit
Species Reactivity : Human
Tested Applications :
Background : Putative catalytic component of the RNA exosome complex which has 3\'->5\' exoribonuclease activity and participates in a m µLtitude of cell µLar RNA processing and degradation events. In the nucleus, the RNA exosome complex is involved in proper maturation of stable RNA species such as rRNA, snRNA and snoRNA, in the elimination of RNA processing by-products and non-coding \'pervasive\' transcripts, such as antisense RNA species and promoter-upstream transcripts (PROMPTs), and of mRNAs with processing defects, thereby limiting or excluding their export to the cytoplasm. The RNA exosome may be involved in Ig class switch recombination (CSR) and/or Ig variable region somatic hypermutation (SHM) by targeting AICDA deamination activity to transcribed dsDNA substrates. In the cytoplasm, the RNA exosome complex is involved in general mRNA turnover and specifically degrades inherently unstable mRNAs containing AU-rich elements (AREs) within their 3\' untranslated regions, and in RNA surveillance pathways, preventing translation of aberrant mRNAs. It seems to be involved in degradation of histone mRNA. EXOSC10 has 3\'-5\' exonuclease activity (By similarity). EXOSC10 is required for nucleolar localization of C1D and probably mediates the association of SKIV2L2, C1D and MPP6 wth the RNA exosome involved in the maturation of 5.8S rRNA.
Clonality : polyclonal Ab
Isotype : IgG
Purification Method : >95%, Protein G purified
Conj µgate : FITC
Buffer : Preservative : 0.03% Proclin 300
Constituents : 50% Glycerol, 0.01M PBS, pH 7.4
Form : Liquid
Stroage : Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
Target Names : EXOSC10
Research Areas : Epigenetics and Nuclear Signaling; Immunology

Volume : 50 µg
Clone Number :
Aliases : Autoantigen PM/Scl 2 antibody; Exosc10 antibody; Exosome component 10 antibody; EXOSX_HUMAN antibody; P100 polymyositis scleroderma overlap syndrome associated autoantigen antibody; P100 polymyositis-scleroderma overlap syndrome-associated autoantigen antibody; p2 antibody; p3 antibody; p4 antibody; PM Scl antibody; PM/Scl 100 antibody; PM/Scl-100 antibody; PMSCL antibody; PMSCL2 antibody; Polymyositis/scleroderma autoantigen 100 kDa antibody; Polymyositis/scleroderma autoantigen 2 100 kDa antibody; Polymyositis/scleroderma autoantigen 2 antibody; RRP6 antibody; Rrp6p antibody
Product Type : polyclonal Ab Antibody
Immunogen Species : Homo sapiens (Human)
UniProt ID : Q01780
Immunogen : Recombinant Human Exosome component 10 protein (587-762AA)
Raised in : Rabbit
Species Reactivity : Human
Tested Applications : ELISA
Background : Putative catalytic component of the RNA exosome complex which has 3\'->5\' exoribonuclease activity and participates in a m µLtitude of cell µLar RNA processing and degradation events. In the nucleus, the RNA exosome complex is involved in proper maturation of stable RNA species such as rRNA, snRNA and snoRNA, in the elimination of RNA processing by-products and non-coding \'pervasive\' transcripts, such as antisense RNA species and promoter-upstream transcripts (PROMPTs), and of mRNAs with processing defects, thereby limiting or excluding their export to the cytoplasm. The RNA exosome may be involved in Ig class switch recombination (CSR) and/or Ig variable region somatic hypermutation (SHM) by targeting AICDA deamination activity to transcribed dsDNA substrates. In the cytoplasm, the RNA exosome complex is involved in general mRNA turnover and specifically degrades inherently unstable mRNAs containing AU-rich elements (AREs) within their 3\' untranslated regions, and in RNA surveillance pathways, preventing translation of aberrant mRNAs. It seems to be involved in degradation of histone mRNA. EXOSC10 has 3\'-5\' exonuclease activity (By similarity). EXOSC10 is required for nucleolar localization of C1D and probably mediates the association of SKIV2L2, C1D and MPP6 wth the RNA exosome involved in the maturation of 5.8S rRNA.
Clonality : polyclonal Ab
Isotype : IgG
Purification Method : >95%, Protein G purified
Conj µgate : Biotin
Buffer : Preservative : 0.03% Proclin 300
Constituents : 50% Glycerol, 0.01M PBS, pH 7.4
Form : Liquid
Stroage : Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
Target Names : EXOSC10
Research Areas : Epigenetics and Nuclear Signaling; Immunology

Volume : 100 µL
Host : Rabbit
Clonality : polyclonal Ab
Isotype : IgG
GeneName : EXOSC10
GeneID : 5394
Uniprot : Q01780
Specificity : EXOSC10 Antibody detects endogenous levels of total EXOSC10.
Immunogen : A syntheVolumed peptide derived from human EXOSC10, corresponding to a region within the internal amino acids.
Storage : Rabbit IgG in phosphate buffered saline , pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol.Store at -20 °C.Stable for 12 months from date of receipt.
Reactivity : Human,Mouse,Rat
Prediction : Pig,Bovine,Horse,Sheep,Rabbit,Dog
Application : WB
Dilution : WB 1 : 500-1 : 2000
Conj µgate : Unconj µgated
RRID : AB_2845951
An Introduction to Blocking Peptides : A superior strategy for validation of antibody binding is the use of blocking peptides. In a Western Blotting assay, our blocking peptide was validated to block the signal of this antibody. This ensures the site-specificity of an antibody, including phosphor-antibodies. In the case of the phosphor- antibodies, the antibodies can and will only recognize the phosphorylated target protein at the corresponding site, not the non-phosphorylated target protein or target protein phosphorylated at a different site.
Cat# Blocking Peptide : DF12990-BP
Des# Blocking Peptide : EXOSC10 Blocking peptide
Blocking Peptide Price : $549 CAD

Volume : 50 µg
Clone Number :
Aliases : 3'-5' exoribonuclease CSL4 homolog antibody; CGI 108 antibody; CGI-108 antibody; CSL4 antibody; CSL4 exosomal core protein homolog antibody; CSL4, S. cerevisiae, homolog of antibody; Csl4p antibody; EXOS1_HUMAN antibody; Exosc1 antibody; Exosomal core protein CSL4 antibody; Exosome complex component csl4 antibody; Exosome component 1 antibody; hCsl4p antibody; Homolog of yeast exosomal core protein CSL4 antibody; p13 antibody; RP11-452K12.9 antibody; SKI4 antibody; Ski4p antibody
Product Type : polyclonal Ab Antibody
Immunogen Species : Homo sapiens (Human)
UniProt ID : Q9Y3B2
Immunogen : Recombinant Human Exosome complex component CSL4 protein (9-195AA)
Raised in : Rabbit
Species Reactivity : Human
Tested Applications : ELISA
Background : Non-catalytic component of the RNA exosome complex which has 3\'->5\' exoribonuclease activity and participates in a m µLtitude of cell µLar RNA processing and degradation events. In the nucleus, the RNA exosome complex is involved in proper maturation of stable RNA species such as rRNA, snRNA and snoRNA, in the elimination of RNA processing by-products and non-coding \'pervasive\' transcripts, such as antisense RNA species and promoter-upstream transcripts (PROMPTs), and of mRNAs with processing defects, thereby limiting or excluding their export to the cytoplasm. The RNA exosome may be involved in Ig class switch recombination (CSR) and/or Ig variable region somatic hypermutation (SHM) by targeting AICDA deamination activity to transcribed dsDNA substrates. In the cytoplasm, the RNA exosome complex is involved in general mRNA turnover and specifically degrades inherently unstable mRNAs containing AU-rich elements (AREs) within their 3\' untranslated regions, and in RNA surveillance pathways, preventing translation of aberrant mRNAs. It seems to be involved in degradation of histone mRNA. The catalytic inactive RNA exosome core complex of 9 subunits (Exo-9) is proposed to play a pivotal role in the binding and presentation of RNA for ribonucleolysis, and to serve as a scaffold for the association with catalytic subunits and accessory proteins or complexes. EXOSC1 as peripheral part of the Exo-9 complex stabilizes the hexameric ring of RNase PH-domain subunits thro µgh contacts with EXOSC6 and EXOSC8.
Clonality : polyclonal Ab
Isotype : IgG
Purification Method : >95%, Protein G purified
Conj µgate : HRP
Buffer : Preservative : 0.03% Proclin 300
Constituents : 50% Glycerol, 0.01M PBS, PH 7.4
Form : Liquid
Stroage : Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
Target Names : EXOSC1
Research Areas : Epigenetics and Nuclear Signaling

Volume : 50 µg
Clone Number :
Aliases : 3'-5' exoribonuclease CSL4 homolog antibody; CGI 108 antibody; CGI-108 antibody; CSL4 antibody; CSL4 exosomal core protein homolog antibody; CSL4, S. cerevisiae, homolog of antibody; Csl4p antibody; EXOS1_HUMAN antibody; Exosc1 antibody; Exosomal core protein CSL4 antibody; Exosome complex component csl4 antibody; Exosome component 1 antibody; hCsl4p antibody; Homolog of yeast exosomal core protein CSL4 antibody; p13 antibody; RP11-452K12.9 antibody; SKI4 antibody; Ski4p antibody
Product Type : polyclonal Ab Antibody
Immunogen Species : Homo sapiens (Human)
UniProt ID : Q9Y3B2
Immunogen : Recombinant Human Exosome complex component CSL4 protein (9-195AA)
Raised in : Rabbit
Species Reactivity : Human
Tested Applications :
Background : Non-catalytic component of the RNA exosome complex which has 3\'->5\' exoribonuclease activity and participates in a m µLtitude of cell µLar RNA processing and degradation events. In the nucleus, the RNA exosome complex is involved in proper maturation of stable RNA species such as rRNA, snRNA and snoRNA, in the elimination of RNA processing by-products and non-coding \'pervasive\' transcripts, such as antisense RNA species and promoter-upstream transcripts (PROMPTs), and of mRNAs with processing defects, thereby limiting or excluding their export to the cytoplasm. The RNA exosome may be involved in Ig class switch recombination (CSR) and/or Ig variable region somatic hypermutation (SHM) by targeting AICDA deamination activity to transcribed dsDNA substrates. In the cytoplasm, the RNA exosome complex is involved in general mRNA turnover and specifically degrades inherently unstable mRNAs containing AU-rich elements (AREs) within their 3\' untranslated regions, and in RNA surveillance pathways, preventing translation of aberrant mRNAs. It seems to be involved in degradation of histone mRNA. The catalytic inactive RNA exosome core complex of 9 subunits (Exo-9) is proposed to play a pivotal role in the binding and presentation of RNA for ribonucleolysis, and to serve as a scaffold for the association with catalytic subunits and accessory proteins or complexes. EXOSC1 as peripheral part of the Exo-9 complex stabilizes the hexameric ring of RNase PH-domain subunits thro µgh contacts with EXOSC6 and EXOSC8.
Clonality : polyclonal Ab
Isotype : IgG
Purification Method : >95%, Protein G purified
Conj µgate : FITC
Buffer : Preservative : 0.03% Proclin 300
Constituents : 50% Glycerol, 0.01M PBS, PH 7.4
Form : Liquid
Stroage : Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
Target Names : EXOSC1
Research Areas : Epigenetics and Nuclear Signaling

Volume : 50 µg
Clone Number :
Aliases : 3'-5' exoribonuclease CSL4 homolog antibody; CGI 108 antibody; CGI-108 antibody; CSL4 antibody; CSL4 exosomal core protein homolog antibody; CSL4, S. cerevisiae, homolog of antibody; Csl4p antibody; EXOS1_HUMAN antibody; Exosc1 antibody; Exosomal core protein CSL4 antibody; Exosome complex component csl4 antibody; Exosome component 1 antibody; hCsl4p antibody; Homolog of yeast exosomal core protein CSL4 antibody; p13 antibody; RP11-452K12.9 antibody; SKI4 antibody; Ski4p antibody
Product Type : polyclonal Ab Antibody
Immunogen Species : Homo sapiens (Human)
UniProt ID : Q9Y3B2
Immunogen : Recombinant Human Exosome complex component CSL4 protein (9-195AA)
Raised in : Rabbit
Species Reactivity : Human
Tested Applications : ELISA
Background : Non-catalytic component of the RNA exosome complex which has 3\'->5\' exoribonuclease activity and participates in a m µLtitude of cell µLar RNA processing and degradation events. In the nucleus, the RNA exosome complex is involved in proper maturation of stable RNA species such as rRNA, snRNA and snoRNA, in the elimination of RNA processing by-products and non-coding \'pervasive\' transcripts, such as antisense RNA species and promoter-upstream transcripts (PROMPTs), and of mRNAs with processing defects, thereby limiting or excluding their export to the cytoplasm. The RNA exosome may be involved in Ig class switch recombination (CSR) and/or Ig variable region somatic hypermutation (SHM) by targeting AICDA deamination activity to transcribed dsDNA substrates. In the cytoplasm, the RNA exosome complex is involved in general mRNA turnover and specifically degrades inherently unstable mRNAs containing AU-rich elements (AREs) within their 3\' untranslated regions, and in RNA surveillance pathways, preventing translation of aberrant mRNAs. It seems to be involved in degradation of histone mRNA. The catalytic inactive RNA exosome core complex of 9 subunits (Exo-9) is proposed to play a pivotal role in the binding and presentation of RNA for ribonucleolysis, and to serve as a scaffold for the association with catalytic subunits and accessory proteins or complexes. EXOSC1 as peripheral part of the Exo-9 complex stabilizes the hexameric ring of RNase PH-domain subunits thro µgh contacts with EXOSC6 and EXOSC8.
Clonality : polyclonal Ab
Isotype : IgG
Purification Method : >95%, Protein G purified
Conj µgate : Biotin
Buffer : Preservative : 0.03% Proclin 300
Constituents : 50% Glycerol, 0.01M PBS, PH 7.4
Form : Liquid
Stroage : Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
Target Names : EXOSC1
Research Areas : Epigenetics and Nuclear Signaling

Volume : 100 µg
Purification : Immunogen affinity purified
Form : liquid
Purity : 95% as determined by SDS-PAGE
Host : Rabbit
Clonality : polyclonal Ab
Clone ID :
Isotype : IgG
Storage : PBS with 0.02% sodium azide and 50% glycerol pH 7.3,-20? for 12 months(Avoid repeated freeze / thaw cycles.)
Background : Non-catalytic component of the RNA exosome complex which has 3'->5' exoribonuclease activity and participates in a m µLtitude of cell µLar RNA processing and degradation events. In the nucleus, the RNA exosome complex is involved in proper maturation of stable RNA species such as rRNA, snRNA and snoRNA, in the elimination of RNA processing by-products and non-coding 'pervasive' transcripts, such as antisense RNA species and promoter-upstream transcripts(PROMPTs), and of mRNAs with processing defects, thereby limiting or excluding their export to the cytoplasm. The RNA exosome may be involved in Ig class switch recombination(CSR) and/or Ig variable region somatic hypermutation(SHM) by targeting AICDA deamination activity to transcribed dsDNA substrates. In the cytoplasm, the RNA exosome complex is involved in general mRNA turnover and specifically degrades inherently unstable mRNAs containing AU-rich elements(AREs) within their 3' untranslated regions, and in RNA surveillance pathways, preventing translation of aberrant mRNAs. It seems to be involved in degradation of histone mRNA. The catalytic inactive RNA exosome core complex of 9 subunits(Exo-9) is proposed to play a pivotal role in the binding and presentation of RNA for ribonucleolysis, and to serve as a scaffold for the association with catalytic subunits and accessory proteins or complexes. EXOSC1 as peripheral part of the Exo-9 complex stabilizes the hexameric ring of RNase PH-domain subunits thro µgh contacts with EXOSC6 and EXOSC8.
Immunogen : exosome component 1
Aliases : CSL4
Observed MW : 21 kDa
Uniprot ID : Q9Y3B2
Reactivity : Human, Mouse, Rat
Application : ELISA, WB, IHC
Recommended dilution : WB : 1 : 500-1 : 2000; IHC : 1 : 20-1 : 200
Gene ID : 51013
Research Area : Immunology, Metabolism

Volume : 100 µg
Purification : Immunogen affinity purified
Form : liquid
Purity : 95% as determined by SDS-PAGE
Host : Rabbit
Clonality : polyclonal Ab
Clone ID :
Isotype : IgG
Storage : PBS with 0.02% sodium azide and 50% glycerol pH 7.3,-20? for 12 months(Avoid repeated freeze / thaw cycles.)
Background : Endo/exonuclease with nicking activity towards supercoiled DNA, a preference for single-stranded DNA and 5'-3' exonuclease activity.
Immunogen : endo/exonuclease(5'-3'), endonuclease G-like
Aliases : ENDOGL1 ENDOGL2, ENGL
Observed MW : 45 kDa
Uniprot ID : Q9Y2C4
Reactivity : Human, Mouse, Rat
Application : ELISA, WB
Recommended dilution : WB : 1 : 500-1 : 2000
Gene ID : 9941
Research Area : Metabolism

Volume : 50 µL
Clone Number :
Aliases : EXO84 antibody; Exo84p antibody; exoc8 antibody; EXOC8_HUMAN antibody; Exocyst complex 84 kDa subunit antibody; Exocyst complex component 8 antibody; SEC84 antibody
Product Type : polyclonal Ab Antibody
Immunogen Species : Homo sapiens (Human)
UniProt ID : Q8IYI6
Immunogen : Recombinant Human Exocyst complex component 8 protein (508-725AA)
Raised in : Rabbit
Species Reactivity : Human
Tested Applications : ELISA
Background : Component of the exocyst complex involved in the docking of exocytic vesicles with fusion sites on the plasma membrane.
Clonality : polyclonal Ab
Isotype : IgG
Purification Method : Antigen Affinity Purified
Conj µgate : HRP
Buffer : Preservative : 0.03% Proclin 300
Constituents : 50% Glycerol, 0.01M PBS, pH 7.4
Form : Liquid
Stroage : Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
Target Names : EXOC8
Research Areas : Signal transduction

Volume : 50 µL
Clone Number :
Aliases : EXO84 antibody; Exo84p antibody; exoc8 antibody; EXOC8_HUMAN antibody; Exocyst complex 84 kDa subunit antibody; Exocyst complex component 8 antibody; SEC84 antibody
Product Type : polyclonal Ab Antibody
Immunogen Species : Homo sapiens (Human)
UniProt ID : Q8IYI6
Immunogen : Recombinant Human Exocyst complex component 8 protein (508-725AA)
Raised in : Rabbit
Species Reactivity : Human
Tested Applications :
Background : Component of the exocyst complex involved in the docking of exocytic vesicles with fusion sites on the plasma membrane.
Clonality : polyclonal Ab
Isotype : IgG
Purification Method : Antigen Affinity Purified
Conj µgate : FITC
Buffer : Preservative : 0.03% Proclin 300
Constituents : 50% Glycerol, 0.01M PBS, pH 7.4
Form : Liquid
Stroage : Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
Target Names : EXOC8
Research Areas : Signal transduction