AChR alpha3 Antibody

AChR α3 Antibody is a highly specific antibody directed against the alpha3 subunit of the nicotinic acetylcholine receptor (AChRα3), a ligand-gated ion channel critical for neuronal synaptic transmission in the peripheral and central nervous systems.

The AChRα3 subunit forms heteropentameric receptor complexes that mediate fast cholinergic signaling at autonomic ganglia and certain CNS neurons. This antibody enables precise detection of AChRα3 expression, localization, and regulation in neuronal cells and tissues.

Typical features:

• Host species: Rabbit or mouse
• Type: Polyclonal or monoclonal antibody
• Immunogen: Synthetic peptide or recombinant fragment of human AChRα3 (CHRNA3)
• Applications: WB, IHC, IF, ICC, ELISA
• Reactivity: Human, rat, mouse
• Storage: −20 °C or −80 °C; avoid repeated freeze–thaw cycles

In summary, the AChR α3 antibody is a critical reagent for studies on neurotransmission, receptor assembly, neurodegeneration, and synaptic plasticity involving cholinergic pathways