Volume : 96-test Kit. Other Volumes are also available. Please contact us.
Assay Type : Sandwich
Detection Range :
Sensitivity :
Species : Chicken
GeneName : ACAN
Alternative Names : Cartilage-specific proteoglycan core protein,CSPCP,AGC1
Uniport : P07898

Volume : 96-test Kit. Other Volumes are also available. Please contact us.
Assay Type :
Detection Range :
Sensitivity :
Species : Chicken
GeneName : ACAC
Alternative Names : ACC
Uniport : P11029

Volume : 96-test Kit. Other Volumes are also available. Please contact us.
Assay Type :
Detection Range :
Sensitivity :
Species : Chicken
GeneName : ABCC1
Alternative Names : ATP-binding cassette sub-family C member 1Leukotriene C(4) transporter,LTC4 transporter,MRP1RCJMB04_32d20
Uniport : Q5F364

Volume : 96-test Kit. Other Volumes are also available. Please contact us.
Assay Type :
Detection Range :
Sensitivity :
Species : Chicken
GeneName : AANAT
Alternative Names : Serotonin acetylase,Aralkylamine N-acetyltransferase,AA-NAT,SNAT
Uniport : P79774

Volume : 96 Test
Species : Chicken
Uniprot ID : Q8JIG5
Short name : a1AGP
Alias : Alpha-1-Acid Glycoprotein
Sensitivity : 0.094ng/ml
Range : 0.156-10ng/ml
Detection method : Sandwich ELISA, Double Antibody
Storage_tempeRature : 2-8 °C for 6 months
Research Area : Immunology

Volume : 96 Test
Species : Chicken
Uniprot ID : P84407
Short name : ?FP
Alias : ?FP|Alpha-Fetoprotein|AFP|FETA|HPAFP|oralpha fetal protein
Sensitivity : 18.75pg/ml
Range : 31.25-2000pg/ml
Detection method : Sandwich ELISA, Double Antibody
Storage_tempeRature : 2-8 °C for 6 months
Research Area : Immunology, Cardiovasc µLar, Cancer, Developmental biology, Stem Cells

Species Reactivity : Chicken (Gallus)
UniProt : Q5ZJ00
Abbreviation : MPP1
Alternative Names : AAG12; DXS552E; EMP55; MRG1; PEMP; aging-associated gene 12|erythrocyte membrane protein p55|migration-related gene 1|palmitoylated erythrocyte membrane protein|palmitoylated membrane protein 1
Application : ELISA
Range : Request Information
Sensitivity : Request Information
Intra-AssayCV : ?4.1%
Inter-AssayCV : ?7.8%
Recovery : 0.89
Sample Type : Serum, Plasma, Other biological fluids
Detection Method : Sandwich
Analysis Method?? : Quantitive
Test principle : This assay employs a two-site sandwich ELISA to quantitate MPP1 in samples. An antibody specific for MPP1 has been pre-coated onto a microplate. Standards and samples are pipetted into the wells and anyMPP1 present is bound by the immobilized antibody. After removing any unbound substances, a biotin-conj µgated antibody specific for MPP1 is added to the wells. After washing, Streptavidin conj µgated Horseradish Peroxidase (HRP) is added to the wells. Following a wash to remove any unbound avidin-enzyme reagent, a substrate solution is added to the wells and color develops in proportion to the amount of MPP1 bound in the initial step. The color development is stopped and the intensity of the color is measured.
Product Overview :
Stability : The stability of ELISA kit is determined by the loss rate of activity. The loss rate of this kit is less than 5% within the expiration date under appropriate storage condition. The loss rate was determined by accelerated thermal degradation test. Keep the kit at 37°C for 4 and 7 days, and compare O.D.values of the kit kept at 37°C with that of at recommended temperature. (referring from China Biological Products Standard, which was calc µLated by the Arrhenius equation. For ELISA kit, 4 days storage at 37°C can be considered as 6 months at 2 - 8°C, which means 7 days at 37°C equaling 12 months at 2 - 8°C).

Species Reactivity : Chicken (Gallus)
UniProt :
Abbreviation : HPGD
Alternative Names : 15-PGDH; PGDH; PGDH1; SDR36C1; NAD+-dependent 15-hydroxyprostaglandin dehydrogenase|short chain dehydrogenase/reductase family 36C; member 1
Application :
Range : Request Information
Sensitivity : Request Information
Intra-AssayCV :
Inter-AssayCV :
Recovery :
Sample Type : Serum, Plasma, Other biological fluids
Detection Method :
Analysis Method?? :
Test principle :
Product Overview :
Stability :

Volume : 96 Tests. Other Volumes are also available. Please Inquire.
Research topic : Others
Uniprot ID : Q5F3W6
Species : Chicken
Former Code :
Alias : 14-3-3GAMMA, 14-3-3 gamma
Product Type : ELISA Kit
Sample Type : serum, plasma, tissue homogenates, cell lysates
Detect Range : 0.156 ng/ml-10 ng/ml
Sensitivity : 0.039 ng/ml
Antigen Name : tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein, gamma polypeptide
Abbreviation : YWHAG
Protein Biological Process 1 :
Protein Biological Process 2 :
Protein Biological Process 3 :
Assay Time : 1-5h
Sample Volume : 50-100 µL
Detection Wavelength : 450 nm
Delievery Date : 7-14 working days

Species Reactivity : Chicken (Gallus)
UniProt :
Abbreviation : PGFM
Alternative Names : N/A
Application :
Range : Request Information
Sensitivity : Request Information
Intra-AssayCV :
Inter-AssayCV :
Recovery :
Sample Type : Serum, Plasma, Other biological fluids
Detection Method :
Analysis Method?? :
Test principle :
Product Overview :
Stability :

Volume : 96 Test
Species : Chicken
Uniprot ID :
Short name : NPT
Alias : NPT|Neopterin
Sensitivity : 0.094ng/ml
Range : 0.156-10ng/ml
Detection method : Competitive ELISA, Coated with Antigen
Storage_tempeRature : 2-8 °C for 6 months
Research Area :

Volume : 50 µL
Clone Number :
Aliases : BrX-like translocated in leukemia antibody; BTL antibody; Chic2 antibody; CHIC2_HUMAN antibody; Cystein-rich hydrophobic domain 2 antibody; Cysteine-rich hydrophobic domain 2 protein antibody; MGC21173 antibody
Product Type : polyclonal Ab Antibody
Immunogen Species : Homo sapiens (Human)
UniProt ID : Q9UKJ5
Immunogen : Recombinant Human Cysteine-rich hydrophobic domain-containing protein 2 protein (1-165AA)
Raised in : Rabbit
Species Reactivity : Human
Tested Applications : ELISA, IHC; Recommended dilution : IHC : 1 : 20-1 : 200
Background : Golgi-associated vesicle, plasma membrane, Golgi to plasma membrane transport
Clonality : polyclonal Ab
Isotype : IgG
Purification Method : Antigen Affinity Purified
Conj µgate : Non-conj µgated
Buffer : PBS with 0.02% sodium azide, 50% glycerol, pH7.3.
Form : Liquid
Stroage : Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
Target Names : CHIC2
Research Areas : Others

Volume : 100 µg
Purification : Immunogen affinity purified
Form : liquid
Purity : 95% as determined by SDS-PAGE
Host : Rabbit
Clonality : polyclonal Ab
Clone ID :
Isotype : IgG
Storage : PBS with 0.02% sodium azide and 50% glycerol pH 7.3 , -20? for 12 months (Avoid repeated freeze / thaw cycles.)
Background : The protein encoded by this gene degrades chitin, which is found in the cell wall of most fungi as well as in arthropods and some nematodes. The encoded protein can also stim µLate interleukin 13 expression, and variations in this gene can lead to asthma susceptibility. Several transcript variants encoding a few different isoforms have been found for this gene.
Immunogen : chitinase, acidic
Aliases :
Observed MW : 52 kDa
Uniprot ID : Q9BZP6
Reactivity : Human, Mouse, Rat
Application : ELISA, WB, IHC
Recommended dilution : WB : 1 : 500 - 1 : 2000; IHC : 1 : 50 - 1 : 200
Gene ID : 27159
Research Area : Metabolism

Volume : 50 µg
Clone Number :
Aliases : CH3L2_HUMAN antibody; CHI3L2 antibody; Chitinase 3 like 2 antibody; Chitinase-3-like protein 2 antibody; Chondrocyte protein 39 antibody; OTTHUMP00000014028 antibody; YKL 39 antibody; YKL-39 antibody; YKL39 antibody
Product Type : polyclonal Ab Antibody
Immunogen Species : Homo sapiens (Human)
UniProt ID : Q15782
Immunogen : Recombinant Human Chitinase-3-like protein 2 protein (27-390AA)
Raised in : Rabbit
Species Reactivity : Human
Tested Applications : ELISA
Background : Lectin that binds chitooligosaccharides and other glycans with high affinity, but not heparin. Has no chitinase activity.
Clonality : polyclonal Ab
Isotype : IgG
Purification Method : >95%, Protein G purified
Conj µgate : HRP
Buffer : Preservative : 0.03% Proclin 300
Constituents : 50% Glycerol, 0.01M PBS, PH 7.4
Form : Liquid
Stroage : Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
Target Names : CHI3L2
Research Areas : Stem cells

Volume : 50 µg
Clone Number :
Aliases : CH3L2_HUMAN antibody; CHI3L2 antibody; Chitinase 3 like 2 antibody; Chitinase-3-like protein 2 antibody; Chondrocyte protein 39 antibody; OTTHUMP00000014028 antibody; YKL 39 antibody; YKL-39 antibody; YKL39 antibody
Product Type : polyclonal Ab Antibody
Immunogen Species : Homo sapiens (Human)
UniProt ID : Q15782
Immunogen : Recombinant Human Chitinase-3-like protein 2 protein (27-390AA)
Raised in : Rabbit
Species Reactivity : Human
Tested Applications :
Background : Lectin that binds chitooligosaccharides and other glycans with high affinity, but not heparin. Has no chitinase activity.
Clonality : polyclonal Ab
Isotype : IgG
Purification Method : >95%, Protein G purified
Conj µgate : FITC
Buffer : Preservative : 0.03% Proclin 300
Constituents : 50% Glycerol, 0.01M PBS, PH 7.4
Form : Liquid
Stroage : Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
Target Names : CHI3L2
Research Areas : Stem cells

Volume : 50 µg
Clone Number :
Aliases : CH3L2_HUMAN antibody; CHI3L2 antibody; Chitinase 3 like 2 antibody; Chitinase-3-like protein 2 antibody; Chondrocyte protein 39 antibody; OTTHUMP00000014028 antibody; YKL 39 antibody; YKL-39 antibody; YKL39 antibody
Product Type : polyclonal Ab Antibody
Immunogen Species : Homo sapiens (Human)
UniProt ID : Q15782
Immunogen : Recombinant Human Chitinase-3-like protein 2 protein (27-390AA)
Raised in : Rabbit
Species Reactivity : Human
Tested Applications : ELISA
Background : Lectin that binds chitooligosaccharides and other glycans with high affinity, but not heparin. Has no chitinase activity.
Clonality : polyclonal Ab
Isotype : IgG
Purification Method : >95%, Protein G purified
Conj µgate : Biotin
Buffer : Preservative : 0.03% Proclin 300
Constituents : 50% Glycerol, 0.01M PBS, PH 7.4
Form : Liquid
Stroage : Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
Target Names : CHI3L2
Research Areas : Stem cells

Volume : 50 µL
Clone Number :
Aliases : CH3L2_HUMAN antibody; CHI3L2 antibody; Chitinase 3 like 2 antibody; Chitinase-3-like protein 2 antibody; Chondrocyte protein 39 antibody; OTTHUMP00000014028 antibody; YKL 39 antibody; YKL-39 antibody; YKL39 antibody
Product Type : polyclonal Ab Antibody
Immunogen Species : Homo sapiens (Human)
UniProt ID : Q15782
Immunogen : Recombinant Human Chitinase-3-like protein 2 protein (27-390AA)
Raised in : Rabbit
Species Reactivity : Human, Rat
Tested Applications : ELISA, WB, IHC; Recommended dilution : WB : 1 : 500-1 : 2000, IHC : 1 : 20-1 : 200
Background : Lectin that binds chitooligosaccharides and other glycans with high affinity, but not heparin. Has no chitinase activity.
Clonality : polyclonal Ab
Isotype : IgG
Purification Method : Antigen Affinity Purified
Conj µgate : Non-conj µgated
Buffer : PBS with 0.02% sodium azide, 50% glycerol, pH7.3.
Form : Liquid
Stroage : Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
Target Names : CHI3L2
Research Areas : Stem cells

Volume : 100 µL
Host : Rabbit
Clonality : polyclonal Ab
Isotype : IgG
GeneName : CHI3L1
GeneID : 1116
Uniprot : P36222
Specificity : CHI3L1 Antibody detects endogenous levels of total CHI3L1.
Immunogen : A syntheVolumed peptide derived from human CHI3L1 corresponding to a region within the internal amino acids.
Storage : Rabbit IgG in phosphate buffered saline , pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol.Store at -20 °C.Stable for 12 months from date of receipt.
Reactivity : Human,Mouse,Rat
Prediction : Pig,Bovine,Rabbit,Dog
Application : WB,IHC,ELISA(peptide)
Dilution : WB 1 : 500-1 : 2000, IHC 1 : 50-1 : 200, ELISA(peptide) 1 : 20000-1 : 40000
Conj µgate : Unconj µgated
RRID : AB_2838539
An Introduction to Blocking Peptides : A superior strategy for validation of antibody binding is the use of blocking peptides. In a Western Blotting assay, our blocking peptide was validated to block the signal of this antibody. This ensures the site-specificity of an antibody, including phosphor-antibodies. In the case of the phosphor- antibodies, the antibodies can and will only recognize the phosphorylated target protein at the corresponding site, not the non-phosphorylated target protein or target protein phosphorylated at a different site.
Cat# Blocking Peptide : DF6577-BP
Des# Blocking Peptide : CHI3L1 Blocking peptide
Blocking Peptide Price : $549 CAD

Volume : 50 µg
Clone Number :
Aliases : CCB peptide antibody; Cg B antibody; CgB antibody; Chgb antibody; Chromogranin-B antibody; ChromograninB antibody; SCG1 antibody; SCG1_HUMAN antibody; Secretogranin 1 antibody; Secretogranin B antibody; Secretogranin I antibody; SgI antibody
Product Type : polyclonal Ab Antibody
Immunogen Species : Homo sapiens (Human)
UniProt ID : P05060
Immunogen : Recombinant Human Secretogranin-1 protein (328-677AA)
Raised in : Rabbit
Species Reactivity : Human
Tested Applications : ELISA
Background : Secretogranin-1 is a neuroendocrine secretory gran µLe protein, which may be the precursor for other biologically active peptides.
Clonality : polyclonal Ab
Isotype : IgG
Purification Method : >95%, Protein G purified
Conj µgate : HRP
Buffer : Preservative : 0.03% Proclin 300
Constituents : 50% Glycerol, 0.01M PBS, PH 7.4
Form : Liquid
Stroage : Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
Target Names : CHGB
Research Areas : Neuroscience; Signal transduction

Volume : 50 µg
Clone Number :
Aliases : CCB peptide antibody; Cg B antibody; CgB antibody; Chgb antibody; Chromogranin-B antibody; ChromograninB antibody; SCG1 antibody; SCG1_HUMAN antibody; Secretogranin 1 antibody; Secretogranin B antibody; Secretogranin I antibody; SgI antibody
Product Type : polyclonal Ab Antibody
Immunogen Species : Homo sapiens (Human)
UniProt ID : P05060
Immunogen : Recombinant Human Secretogranin-1 protein (328-677AA)
Raised in : Rabbit
Species Reactivity : Human
Tested Applications :
Background : Secretogranin-1 is a neuroendocrine secretory gran µLe protein, which may be the precursor for other biologically active peptides.
Clonality : polyclonal Ab
Isotype : IgG
Purification Method : >95%, Protein G purified
Conj µgate : FITC
Buffer : Preservative : 0.03% Proclin 300
Constituents : 50% Glycerol, 0.01M PBS, PH 7.4
Form : Liquid
Stroage : Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
Target Names : CHGB
Research Areas : Neuroscience; Signal transduction

Volume : 50 µg
Clone Number :
Aliases : CCB peptide antibody; Cg B antibody; CgB antibody; Chgb antibody; Chromogranin-B antibody; ChromograninB antibody; SCG1 antibody; SCG1_HUMAN antibody; Secretogranin 1 antibody; Secretogranin B antibody; Secretogranin I antibody; SgI antibody
Product Type : polyclonal Ab Antibody
Immunogen Species : Homo sapiens (Human)
UniProt ID : P05060
Immunogen : Recombinant Human Secretogranin-1 protein (328-677AA)
Raised in : Rabbit
Species Reactivity : Human
Tested Applications : ELISA
Background : Secretogranin-1 is a neuroendocrine secretory gran µLe protein, which may be the precursor for other biologically active peptides.
Clonality : polyclonal Ab
Isotype : IgG
Purification Method : >95%, Protein G purified
Conj µgate : Biotin
Buffer : Preservative : 0.03% Proclin 300
Constituents : 50% Glycerol, 0.01M PBS, PH 7.4
Form : Liquid
Stroage : Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
Target Names : CHGB
Research Areas : Neuroscience; Signal transduction

Volume : 50 µL
Clone Number :
Aliases : CCB peptide antibody; Cg B antibody; CgB antibody; Chgb antibody; Chromogranin-B antibody; ChromograninB antibody; SCG1 antibody; SCG1_HUMAN antibody; Secretogranin 1 antibody; Secretogranin B antibody; Secretogranin I antibody; SgI antibody
Product Type : polyclonal Ab Antibody
Immunogen Species : Homo sapiens (Human)
UniProt ID : P05060
Immunogen : Human CHGB
Raised in : Rabbit
Species Reactivity : Human
Tested Applications : ELISA, WB
Background :
Clonality : polyclonal Ab
Isotype : IgG
Purification Method : Antigen Affinity purified
Conj µgate : Non-conj µgated
Buffer : PBS with 0.1% Sodium Azide, 50% Glycerol, pH 7.3. -20°C, Avoid freeze / thaw cycles.
Form : Liquid
Stroage : Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
Target Names : CHGB
Research Areas : Neuroscience;Signal transduction

Volume : 50 µg
Clone Number : 1A11C11
Aliases : Chromogranin-A,CgA,Pituitary secretory protein I,SP-I,Vasostatin II,CHGA
Product Type : Monoclonal Antibody
Immunogen Species : Human
UniProt ID : P10645
Immunogen : Recombinant CHGA Protein
Raised in : Mouse
Species Reactivity : Human
Tested Applications : ELISA,WB,IHC;Recommended dilution : WB : 1 : 500-1 : 5000,IHC : 1 : 50-1 : 500
Background : Chromogranin A is a member of the granin family of neuroendocrine secretory proteins. It is located in secretory vesicles of neurons and endocrine cells. Chromogranin A is the precursor to several functional peptides including vasostatin, pancreastatin, catestatin and parastatin. These peptides negatively mod µLate the neuroendocrine function of the releasing cell (autocrine) or nearby cells (paracrine). CgA is one of the most used tumor markers in NET's (neuroendocrine tumors) , and elevated CgA concentrations have been demonstrated in serum or plasma of patients with different types of these tumors. However, CgA is not a tumor-specific antigen for NETs, and an abnormal concentration has been described in some non-malignant diseases such as renal failure, heart failure, proton pump inhibition, gastritis, hypertension, or patients with liver diseases.
Clonality : Monoclonal
Isotype : IgG1
Purification Method : >95%,Protein G purified
Conj µgate : Non-conj µgated
Buffer : Preservative : 0.03% Proclin 300
Constituents : 50% Glycerol, 0.01M PBS, PH 7.4
Form : liquid
Stroage : Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
Target Names : CHGA
Research Areas : Neuroscience?Cancer;Tags & Cell Markers;Signal transduction

Volume : 50 µg
Clone Number :
Aliases : beta Granin antibody; betagranin (N-terminal fragment of chromogranin A) antibody; catestatin antibody; CgA antibody; CHG A antibody; Chga antibody; chromofungin antibody; Chromogranin A antibody; Chromogranin A parathyroid secretory protein 1 antibody; Chromogranin A precursor antibody; ChromograninA antibody; CMGA_HUMAN antibody; ER-37 antibody; Pancreastatin antibody; Parastatin antibody; Parathyroid secretory protein 1 antibody; Pituitary secretory protein I antibody; Secretory protein I antibody; SP I antibody; SP-I antibody; SP1 antibody; SPI antibody; vasostatin 2 antibody; Vasostatin antibody; Vasostatin I antibody; Vasostatin II antibody; vasostatin-2 antibody
Product Type : polyclonal Ab Antibody
Immunogen Species : Homo sapiens (Human)
UniProt ID : P10645
Immunogen : Recombinant Human Chromogranin-A protein (19-457AA)
Raised in : Rabbit
Species Reactivity : Human
Tested Applications : ELISA
Background : Pancreastatin strongly inhibits glucose induced ins µLin release from the pancreas.
Clonality : polyclonal Ab
Isotype : IgG
Purification Method : >95%, Protein G purified
Conj µgate : HRP
Buffer : Preservative : 0.03% Proclin 300
Constituents : 50% Glycerol, 0.01M PBS, PH 7.4
Form : Liquid
Stroage : Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
Target Names : CHGA
Research Areas : Neuroscience; Cancer; Tags & Cell Markers; Signal transduction

Volume : 50 µg
Clone Number :
Aliases : beta Granin antibody; betagranin (N-terminal fragment of chromogranin A) antibody; catestatin antibody; CgA antibody; CHG A antibody; Chga antibody; chromofungin antibody; Chromogranin A antibody; Chromogranin A parathyroid secretory protein 1 antibody; Chromogranin A precursor antibody; ChromograninA antibody; CMGA_HUMAN antibody; ER-37 antibody; Pancreastatin antibody; Parastatin antibody; Parathyroid secretory protein 1 antibody; Pituitary secretory protein I antibody; Secretory protein I antibody; SP I antibody; SP-I antibody; SP1 antibody; SPI antibody; vasostatin 2 antibody; Vasostatin antibody; Vasostatin I antibody; Vasostatin II antibody; vasostatin-2 antibody
Product Type : polyclonal Ab Antibody
Immunogen Species : Homo sapiens (Human)
UniProt ID : P10645
Immunogen : Recombinant Human Chromogranin-A protein (19-457AA)
Raised in : Rabbit
Species Reactivity : Human
Tested Applications :
Background : Pancreastatin strongly inhibits glucose induced ins µLin release from the pancreas.
Clonality : polyclonal Ab
Isotype : IgG
Purification Method : >95%, Protein G purified
Conj µgate : FITC
Buffer : Preservative : 0.03% Proclin 300
Constituents : 50% Glycerol, 0.01M PBS, PH 7.4
Form : Liquid
Stroage : Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
Target Names : CHGA
Research Areas : Neuroscience; Cancer; Tags & Cell Markers; Signal transduction

Volume : 50 µg
Clone Number :
Aliases : beta Granin antibody; betagranin (N-terminal fragment of chromogranin A) antibody; catestatin antibody; CgA antibody; CHG A antibody; Chga antibody; chromofungin antibody; Chromogranin A antibody; Chromogranin A parathyroid secretory protein 1 antibody; Chromogranin A precursor antibody; ChromograninA antibody; CMGA_HUMAN antibody; ER-37 antibody; Pancreastatin antibody; Parastatin antibody; Parathyroid secretory protein 1 antibody; Pituitary secretory protein I antibody; Secretory protein I antibody; SP I antibody; SP-I antibody; SP1 antibody; SPI antibody; vasostatin 2 antibody; Vasostatin antibody; Vasostatin I antibody; Vasostatin II antibody; vasostatin-2 antibody
Product Type : polyclonal Ab Antibody
Immunogen Species : Homo sapiens (Human)
UniProt ID : P10645
Immunogen : Recombinant Human Chromogranin-A protein (19-457AA)
Raised in : Rabbit
Species Reactivity : Human
Tested Applications : ELISA
Background : Pancreastatin strongly inhibits glucose induced ins µLin release from the pancreas.
Clonality : polyclonal Ab
Isotype : IgG
Purification Method : >95%, Protein G purified
Conj µgate : Biotin
Buffer : Preservative : 0.03% Proclin 300
Constituents : 50% Glycerol, 0.01M PBS, PH 7.4
Form : Liquid
Stroage : Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
Target Names : CHGA
Research Areas : Neuroscience; Cancer; Tags & Cell Markers; Signal transduction

Volume : 100 µL
Host : Rabbit
Clonality : polyclonal Ab
Isotype : IgG
GeneName : CHGA
GeneID : 1113
Uniprot : P10645
Specificity : CHGA Antibody detects endogenous levels of total CHGA.
Immunogen : A syntheVolumed peptide derived from human CHGA, corresponding to a region within C-terminal amino acids.
Storage : Rabbit IgG in phosphate buffered saline , pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol.Store at -20 °C.Stable for 12 months from date of receipt.
Reactivity : Human,Mouse,Rat
Prediction : Pig,Bovine,Horse,Rabbit
Application : WB,IHC,ELISA(peptide)
Dilution : WB 1 : 1000-3000, IHC 1 : 50-1 : 200, ELISA(peptide) 1 : 20000-1 : 40000
Conj µgate : Unconj µgated
RRID : AB_2841144
An Introduction to Blocking Peptides : A superior strategy for validation of antibody binding is the use of blocking peptides. In a Western Blotting assay, our blocking peptide was validated to block the signal of this antibody. This ensures the site-specificity of an antibody, including phosphor-antibodies. In the case of the phosphor- antibodies, the antibodies can and will only recognize the phosphorylated target protein at the corresponding site, not the non-phosphorylated target protein or target protein phosphorylated at a different site.
Cat# Blocking Peptide : DF7672-BP
Des# Blocking Peptide : CHGA Blocking peptide
Blocking Peptide Price : $549 CAD

Volume : 50 µg
Clone Number :
Aliases : Checkpoint with forkhead and ring finger domains antibody; Checkpoint with forkhead and RING finger domains protein antibody; Chfr antibody; CHFR_HUMAN antibody; E3 ubiquitin protein ligase CHFR antibody; E3 ubiquitin-protein ligase CHFR antibody; EC 6.3.2. antibody; FLJ10796 antibody; FLJ33629 antibody; RING finger protein 196 antibody; RNF 116 antibody; RNF 196 antibody; RNF116 antibody; RNF196 antibody; Ubiquitin ligase protein antibody
Product Type : polyclonal Ab Antibody
Immunogen Species : Homo sapiens (Human)
UniProt ID : Q96EP1
Immunogen : Recombinant Human E3 ubiquitin-protein ligase CHFR protein (141-422AA)
Raised in : Rabbit
Species Reactivity : Human
Tested Applications : ELISA
Background : E3 ubiquitin-protein ligase that functions in the antephase checkpoint by actively delaying passage into mitosis in response to microtub µLe poisons. Acts in early prophase before chromosome condensation, when the centrosome move apart from each other along the periphery of the nucleus. Probably involved in signaling the presence of mitotic stress caused by microtub µLe poisons by mediating the \\\'Lys-48\\\'-linked ubiquitination of target proteins, leading to their degradation by the proteasome. Promotes the ubiquitination and subsequent degradation of AURKA and PLK1. Probably acts as a tumor suppressor, possibly by mediating the polyubiquitination of HDAC1 leading to its degradation. May also promote the formation of \\\'Lys-63\\\'-linked polyubiquitin chains and functions with the specific ubiquitin-conj µgating UBC13-MMS2 (UBE2N-UBE2V2) heterodimer. Substrates that are polyubiquitinated at \\\'Lys-63\\\' are usually not targeted for degradation, but are rather involved in signaling cell µLar stress.
Clonality : polyclonal Ab
Isotype : IgG
Purification Method : >95%, Protein G purified
Conj µgate : HRP
Buffer : Preservative : 0.03% Proclin 300
Constituents : 50% Glycerol, 0.01M PBS, PH 7.4
Form : Liquid
Stroage : Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
Target Names : CHFR
Research Areas : Epigenetics and Nuclear Signaling; Cancer; Cell biology

Volume : 50 µg
Clone Number :
Aliases : Checkpoint with forkhead and ring finger domains antibody; Checkpoint with forkhead and RING finger domains protein antibody; Chfr antibody; CHFR_HUMAN antibody; E3 ubiquitin protein ligase CHFR antibody; E3 ubiquitin-protein ligase CHFR antibody; EC 6.3.2. antibody; FLJ10796 antibody; FLJ33629 antibody; RING finger protein 196 antibody; RNF 116 antibody; RNF 196 antibody; RNF116 antibody; RNF196 antibody; Ubiquitin ligase protein antibody
Product Type : polyclonal Ab Antibody
Immunogen Species : Homo sapiens (Human)
UniProt ID : Q96EP1
Immunogen : Recombinant Human E3 ubiquitin-protein ligase CHFR protein (141-422AA)
Raised in : Rabbit
Species Reactivity : Human
Tested Applications :
Background : E3 ubiquitin-protein ligase that functions in the antephase checkpoint by actively delaying passage into mitosis in response to microtub µLe poisons. Acts in early prophase before chromosome condensation, when the centrosome move apart from each other along the periphery of the nucleus. Probably involved in signaling the presence of mitotic stress caused by microtub µLe poisons by mediating the \\\'Lys-48\\\'-linked ubiquitination of target proteins, leading to their degradation by the proteasome. Promotes the ubiquitination and subsequent degradation of AURKA and PLK1. Probably acts as a tumor suppressor, possibly by mediating the polyubiquitination of HDAC1 leading to its degradation. May also promote the formation of \\\'Lys-63\\\'-linked polyubiquitin chains and functions with the specific ubiquitin-conj µgating UBC13-MMS2 (UBE2N-UBE2V2) heterodimer. Substrates that are polyubiquitinated at \\\'Lys-63\\\' are usually not targeted for degradation, but are rather involved in signaling cell µLar stress.
Clonality : polyclonal Ab
Isotype : IgG
Purification Method : >95%, Protein G purified
Conj µgate : FITC
Buffer : Preservative : 0.03% Proclin 300
Constituents : 50% Glycerol, 0.01M PBS, PH 7.4
Form : Liquid
Stroage : Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
Target Names : CHFR
Research Areas : Epigenetics and Nuclear Signaling; Cancer; Cell biology

Volume : 50 µg
Clone Number :
Aliases : Checkpoint with forkhead and ring finger domains antibody; Checkpoint with forkhead and RING finger domains protein antibody; Chfr antibody; CHFR_HUMAN antibody; E3 ubiquitin protein ligase CHFR antibody; E3 ubiquitin-protein ligase CHFR antibody; EC 6.3.2. antibody; FLJ10796 antibody; FLJ33629 antibody; RING finger protein 196 antibody; RNF 116 antibody; RNF 196 antibody; RNF116 antibody; RNF196 antibody; Ubiquitin ligase protein antibody
Product Type : polyclonal Ab Antibody
Immunogen Species : Homo sapiens (Human)
UniProt ID : Q96EP1
Immunogen : Recombinant Human E3 ubiquitin-protein ligase CHFR protein (141-422AA)
Raised in : Rabbit
Species Reactivity : Human
Tested Applications : ELISA
Background : E3 ubiquitin-protein ligase that functions in the antephase checkpoint by actively delaying passage into mitosis in response to microtub µLe poisons. Acts in early prophase before chromosome condensation, when the centrosome move apart from each other along the periphery of the nucleus. Probably involved in signaling the presence of mitotic stress caused by microtub µLe poisons by mediating the \\\'Lys-48\\\'-linked ubiquitination of target proteins, leading to their degradation by the proteasome. Promotes the ubiquitination and subsequent degradation of AURKA and PLK1. Probably acts as a tumor suppressor, possibly by mediating the polyubiquitination of HDAC1 leading to its degradation. May also promote the formation of \\\'Lys-63\\\'-linked polyubiquitin chains and functions with the specific ubiquitin-conj µgating UBC13-MMS2 (UBE2N-UBE2V2) heterodimer. Substrates that are polyubiquitinated at \\\'Lys-63\\\' are usually not targeted for degradation, but are rather involved in signaling cell µLar stress.
Clonality : polyclonal Ab
Isotype : IgG
Purification Method : >95%, Protein G purified
Conj µgate : Biotin
Buffer : Preservative : 0.03% Proclin 300
Constituents : 50% Glycerol, 0.01M PBS, PH 7.4
Form : Liquid
Stroage : Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
Target Names : CHFR
Research Areas : Epigenetics and Nuclear Signaling; Cancer; Cell biology

Volume : 100 µL
Host : Rabbit
Clonality : polyclonal Ab
Isotype : IgG
GeneName : CHFR
GeneID : 55743
Uniprot : Q96EP1
Specificity : CHFR Antibody detects endogenous levels of total CHFR.
Immunogen : A syntheVolumed peptide derived from human CHFR, corresponding to a region within the internal amino acids.
Storage : Rabbit IgG in phosphate buffered saline , pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol.Store at -20 °C.Stable for 12 months from date of receipt.
Reactivity : Human,Mouse,Rat
Prediction : Pig,Bovine,Sheep,Rabbit,Dog,Xenopus
Application : WB,IHC,IF/ICC,ELISA(peptide)
Dilution : WB 1 : 500-1 : 1000, IF/ICC 1 : 100-1 : 500, IHC 1 : 50-1 : 200, ELISA(peptide) 1 : 20000-1 : 40000
Conj µgate : Unconj µgated
RRID : AB_2837084
An Introduction to Blocking Peptides : A superior strategy for validation of antibody binding is the use of blocking peptides. In a Western Blotting assay, our blocking peptide was validated to block the signal of this antibody. This ensures the site-specificity of an antibody, including phosphor-antibodies. In the case of the phosphor- antibodies, the antibodies can and will only recognize the phosphorylated target protein at the corresponding site, not the non-phosphorylated target protein or target protein phosphorylated at a different site.
Cat# Blocking Peptide : DF4733-BP
Des# Blocking Peptide : CHFR Blocking peptide
Blocking Peptide Price : $549 CAD

Volume : 100 µL
Host : Rabbit
Clonality : polyclonal Ab
Isotype : IgG
GeneName : FOXN3
GeneID : 1112
Uniprot : O00409
Specificity : CHES1 Antibody detects endogenous levels of total CHES1.
Immunogen : A syntheVolumed peptide derived from Human MYOCD.
Storage : Rabbit IgG in phosphate buffered saline , pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol.Store at -20 °C.Stable for 12 months from date of receipt.
Reactivity : Human,Mouse
Prediction :
Application : ELISA(peptide)
Dilution : ELISA(peptide) 1 : 20000-1 : 40000
Conj µgate : Unconj µgated
RRID :
An Introduction to Blocking Peptides : A superior strategy for validation of antibody binding is the use of blocking peptides. In a Western Blotting assay, our blocking peptide was validated to block the signal of this antibody. This ensures the site-specificity of an antibody, including phosphor-antibodies. In the case of the phosphor- antibodies, the antibodies can and will only recognize the phosphorylated target protein at the corresponding site, not the non-phosphorylated target protein or target protein phosphorylated at a different site.
Cat# Blocking Peptide : DF13903-BP
Des# Blocking Peptide : CHES1 Blocking peptide
Blocking Peptide Price : $549 CAD

Volume : 100 µL
Host : Rabbit
Clonality : polyclonal Ab
Isotype : IgG
GeneName : CHERP
GeneID : 10523
Uniprot : Q8IWX8
Specificity : CHERP Antibody detects endogenous levels of total CHERP.
Immunogen : A syntheVolumed peptide derived from human CHERP, corresponding to a region within the internal amino acids.
Storage : Rabbit IgG in phosphate buffered saline , pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol.Store at -20 °C.Stable for 12 months from date of receipt.
Reactivity : Human,Mouse
Prediction : Pig,Bovine,Horse,Sheep,Dog,Chicken,Xenopus
Application : WB,ELISA(peptide)
Dilution : WB 1 : 1000-3000, ELISA(peptide) 1 : 20000-1 : 40000
Conj µgate : Unconj µgated
RRID : AB_2842492
An Introduction to Blocking Peptides : A superior strategy for validation of antibody binding is the use of blocking peptides. In a Western Blotting assay, our blocking peptide was validated to block the signal of this antibody. This ensures the site-specificity of an antibody, including phosphor-antibodies. In the case of the phosphor- antibodies, the antibodies can and will only recognize the phosphorylated target protein at the corresponding site, not the non-phosphorylated target protein or target protein phosphorylated at a different site.
Cat# Blocking Peptide : DF9296-BP
Des# Blocking Peptide : CHERP Blocking peptide
Blocking Peptide Price : $549 CAD

Volume : 50 µg
Clone Number : 4E1D4
Aliases : Chenodiol, chenix, chenic acid, chenodeoxycholate, gallodesoxycholic acid, chendol, chenofalk, chenodesoxycholic acid, CDCA
Product Type : Monoclonal Antibody
Immunogen Species :
UniProt ID :
Immunogen : Chenodeoxycholic acid-BSA conj µgate
Raised in : Mouse
Species Reactivity :
Tested Applications : ELISA
Background :
Clonality : Monoclonal
Isotype : IgG2b
Purification Method : >95%,Protein G purified
Conj µgate : Non-conj µgated
Buffer : Preservative : 0.03% Proclin 300
Constituents : 50% Glycerol, 0.01M PBS, PH 7.4
Form : liquid
Stroage : Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
Target Names : Chenodeoxycholic acid
Research Areas : Others

Volume : 100 µL
Host : Rabbit
Clonality : polyclonal Ab
Isotype : IgG
GeneName : RARRES2
GeneID : 5919
Uniprot : Q99969
Specificity : Chemerin Antibody detects endogenous levels of total Chemerin.
Immunogen : A syntheVolumed peptide derived from Human MYOCD.
Storage : Rabbit IgG in phosphate buffered saline , pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol.Store at -20 °C.Stable for 12 months from date of receipt.
Reactivity : Human
Prediction :
Application : ELISA(peptide)
Dilution : ELISA(peptide) 1 : 20000-1 : 40000
Conj µgate : Unconj µgated
RRID :
An Introduction to Blocking Peptides : A superior strategy for validation of antibody binding is the use of blocking peptides. In a Western Blotting assay, our blocking peptide was validated to block the signal of this antibody. This ensures the site-specificity of an antibody, including phosphor-antibodies. In the case of the phosphor- antibodies, the antibodies can and will only recognize the phosphorylated target protein at the corresponding site, not the non-phosphorylated target protein or target protein phosphorylated at a different site.
Cat# Blocking Peptide : DF14382-BP
Des# Blocking Peptide : Chemerin Blocking peptide
Blocking Peptide Price : $549 CAD

Volume : 50 µg
Clone Number :
Aliases : CDS 1 antibody; Cds1 antibody; Cds1 homolog antibody; Checkpoint kinase 2 antibody; Checkpoint like protein CHK2 antibody; CHEK 2 antibody; Chek2 antibody; Chk 2 antibody; CHK2 checkpoint homolog (S. pombe) antibody; CHK2 checkpoint homolog antibody; CHK2_HUMAN antibody; hCds1 antibody; HuCds 1 antibody; LFS 2 antibody; LFS2 antibody; PP1425 antibody; RAD 53 antibody; RAD53 antibody; Rad53 homolog antibody; Serine/threonine protein kinase Chk2 antibody; Serine/threonine-protein kinase Chk2 antibody
Product Type : polyclonal Ab Antibody
Immunogen Species : Homo sapiens (Human)
UniProt ID : O96017
Immunogen : Recombinant Human Serine/threonine-protein kinase Chk2 protein (1-270AA)
Raised in : Rabbit
Species Reactivity : Human
Tested Applications : ELISA
Background : Serine/threonine-protein kinase which is required for checkpoint-mediated cell cycle arrest, activation of DNA repair and apoptosis in response to the presence of DNA double-strand breaks. May also negatively reg µLate cell cycle progression during unperturbed cell cycles. Following activation, phosphorylates numerous effectors preferentially at the consensus sequence [L-X-R-X-X-S/T]. Reg µLates cell cycle checkpoint arrest thro µgh phosphorylation of CDC25A, CDC25B and CDC25C, inhibiting their activity. Inhibition of CDC25 phosphatase activity leads to increased inhibitory tyrosine phosphorylation of CDK-cyclin complexes and blocks cell cycle progression. May also phosphorylate NEK6 which is involved in G2/M cell cycle arrest. Reg µLates DNA repair thro µgh phosphorylation of BRCA2, enhancing the association of RAD51 with chromatin which promotes DNA repair by homologous recombination. Also stim µLates the transcription of genes involved in DNA repair (including BRCA2) thro µgh the phosphorylation and activation of the transcription factor FOXM1. Reg µLates apoptosis thro µgh the phosphorylation of p53/TP53, MDM4 and PML. Phosphorylation of p53/TP53 at \\\'Ser-20\\\' by CHEK2 may alleviate inhibition by MDM2, leading to accum µLation of active p53/TP53. Phosphorylation of MDM4 may also reduce degradation of p53/TP53. Also controls the transcription of pro-apoptotic genes thro µgh phosphorylation of the transcription factor E2F1. Tumor suppressor, it may also have a DNA damage-independent function in mitotic spindle assembly by phosphorylating BRCA1. Its absence may be a cause of the chromosomal instability observed in some cancer cells. Promotes the CCAR2-SIRT1 association and is required for CCAR2-mediated SIRT1 inhibition (PubMed : 25361978).
Clonality : polyclonal Ab
Isotype : IgG
Purification Method : >95%, Protein G purified
Conj µgate : HRP
Buffer : Preservative : 0.03% Proclin 300
Constituents : 50% Glycerol, 0.01M PBS, PH 7.4
Form : Liquid
Stroage : Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
Target Names : CHEK2
Research Areas : Epigenetics and Nuclear Signaling; Cancer

Volume : 50 µg
Clone Number :
Aliases : CDS 1 antibody; Cds1 antibody; Cds1 homolog antibody; Checkpoint kinase 2 antibody; Checkpoint like protein CHK2 antibody; CHEK 2 antibody; Chek2 antibody; Chk 2 antibody; CHK2 checkpoint homolog (S. pombe) antibody; CHK2 checkpoint homolog antibody; CHK2_HUMAN antibody; hCds1 antibody; HuCds 1 antibody; LFS 2 antibody; LFS2 antibody; PP1425 antibody; RAD 53 antibody; RAD53 antibody; Rad53 homolog antibody; Serine/threonine protein kinase Chk2 antibody; Serine/threonine-protein kinase Chk2 antibody
Product Type : polyclonal Ab Antibody
Immunogen Species : Homo sapiens (Human)
UniProt ID : O96017
Immunogen : Recombinant Human Serine/threonine-protein kinase Chk2 protein (1-270AA)
Raised in : Rabbit
Species Reactivity : Human
Tested Applications :
Background : Serine/threonine-protein kinase which is required for checkpoint-mediated cell cycle arrest, activation of DNA repair and apoptosis in response to the presence of DNA double-strand breaks. May also negatively reg µLate cell cycle progression during unperturbed cell cycles. Following activation, phosphorylates numerous effectors preferentially at the consensus sequence [L-X-R-X-X-S/T]. Reg µLates cell cycle checkpoint arrest thro µgh phosphorylation of CDC25A, CDC25B and CDC25C, inhibiting their activity. Inhibition of CDC25 phosphatase activity leads to increased inhibitory tyrosine phosphorylation of CDK-cyclin complexes and blocks cell cycle progression. May also phosphorylate NEK6 which is involved in G2/M cell cycle arrest. Reg µLates DNA repair thro µgh phosphorylation of BRCA2, enhancing the association of RAD51 with chromatin which promotes DNA repair by homologous recombination. Also stim µLates the transcription of genes involved in DNA repair (including BRCA2) thro µgh the phosphorylation and activation of the transcription factor FOXM1. Reg µLates apoptosis thro µgh the phosphorylation of p53/TP53, MDM4 and PML. Phosphorylation of p53/TP53 at \\\'Ser-20\\\' by CHEK2 may alleviate inhibition by MDM2, leading to accum µLation of active p53/TP53. Phosphorylation of MDM4 may also reduce degradation of p53/TP53. Also controls the transcription of pro-apoptotic genes thro µgh phosphorylation of the transcription factor E2F1. Tumor suppressor, it may also have a DNA damage-independent function in mitotic spindle assembly by phosphorylating BRCA1. Its absence may be a cause of the chromosomal instability observed in some cancer cells. Promotes the CCAR2-SIRT1 association and is required for CCAR2-mediated SIRT1 inhibition (PubMed : 25361978).
Clonality : polyclonal Ab
Isotype : IgG
Purification Method : >95%, Protein G purified
Conj µgate : FITC
Buffer : Preservative : 0.03% Proclin 300
Constituents : 50% Glycerol, 0.01M PBS, PH 7.4
Form : Liquid
Stroage : Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
Target Names : CHEK2
Research Areas : Epigenetics and Nuclear Signaling; Cancer

Volume : 50 µg
Clone Number :
Aliases : CDS 1 antibody; Cds1 antibody; Cds1 homolog antibody; Checkpoint kinase 2 antibody; Checkpoint like protein CHK2 antibody; CHEK 2 antibody; Chek2 antibody; Chk 2 antibody; CHK2 checkpoint homolog (S. pombe) antibody; CHK2 checkpoint homolog antibody; CHK2_HUMAN antibody; hCds1 antibody; HuCds 1 antibody; LFS 2 antibody; LFS2 antibody; PP1425 antibody; RAD 53 antibody; RAD53 antibody; Rad53 homolog antibody; Serine/threonine protein kinase Chk2 antibody; Serine/threonine-protein kinase Chk2 antibody
Product Type : polyclonal Ab Antibody
Immunogen Species : Homo sapiens (Human)
UniProt ID : O96017
Immunogen : Recombinant Human Serine/threonine-protein kinase Chk2 protein (1-270AA)
Raised in : Rabbit
Species Reactivity : Human
Tested Applications : ELISA
Background : Serine/threonine-protein kinase which is required for checkpoint-mediated cell cycle arrest, activation of DNA repair and apoptosis in response to the presence of DNA double-strand breaks. May also negatively reg µLate cell cycle progression during unperturbed cell cycles. Following activation, phosphorylates numerous effectors preferentially at the consensus sequence [L-X-R-X-X-S/T]. Reg µLates cell cycle checkpoint arrest thro µgh phosphorylation of CDC25A, CDC25B and CDC25C, inhibiting their activity. Inhibition of CDC25 phosphatase activity leads to increased inhibitory tyrosine phosphorylation of CDK-cyclin complexes and blocks cell cycle progression. May also phosphorylate NEK6 which is involved in G2/M cell cycle arrest. Reg µLates DNA repair thro µgh phosphorylation of BRCA2, enhancing the association of RAD51 with chromatin which promotes DNA repair by homologous recombination. Also stim µLates the transcription of genes involved in DNA repair (including BRCA2) thro µgh the phosphorylation and activation of the transcription factor FOXM1. Reg µLates apoptosis thro µgh the phosphorylation of p53/TP53, MDM4 and PML. Phosphorylation of p53/TP53 at \\\'Ser-20\\\' by CHEK2 may alleviate inhibition by MDM2, leading to accum µLation of active p53/TP53. Phosphorylation of MDM4 may also reduce degradation of p53/TP53. Also controls the transcription of pro-apoptotic genes thro µgh phosphorylation of the transcription factor E2F1. Tumor suppressor, it may also have a DNA damage-independent function in mitotic spindle assembly by phosphorylating BRCA1. Its absence may be a cause of the chromosomal instability observed in some cancer cells. Promotes the CCAR2-SIRT1 association and is required for CCAR2-mediated SIRT1 inhibition (PubMed : 25361978).
Clonality : polyclonal Ab
Isotype : IgG
Purification Method : >95%, Protein G purified
Conj µgate : Biotin
Buffer : Preservative : 0.03% Proclin 300
Constituents : 50% Glycerol, 0.01M PBS, PH 7.4
Form : Liquid
Stroage : Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
Target Names : CHEK2
Research Areas : Epigenetics and Nuclear Signaling; Cancer

Volume : 50 µg
Clone Number :
Aliases : CDS 1 antibody; Cds1 antibody; Cds1 homolog antibody; Checkpoint kinase 2 antibody; Checkpoint like protein CHK2 antibody; CHEK 2 antibody; Chek2 antibody; Chk 2 antibody; CHK2 checkpoint homolog (S. pombe) antibody; CHK2 checkpoint homolog antibody; CHK2_HUMAN antibody; hCds1 antibody; HuCds 1 antibody; LFS 2 antibody; LFS2 antibody; PP1425 antibody; RAD 53 antibody; RAD53 antibody; Rad53 homolog antibody; Serine/threonine protein kinase Chk2 antibody; Serine/threonine-protein kinase Chk2 antibody
Product Type : polyclonal Ab Antibody
Immunogen Species : Homo sapiens (Human)
UniProt ID : O96017
Immunogen : SyntheVolumed peptide derived from Human Chk2 around the non-phosphorylation site of S516.
Raised in : Rabbit
Species Reactivity : Human
Tested Applications : WB, ELISA; WB : 1 : 500-1 : 2000, ELISA : 1 : 20000
Background :
Clonality : polyclonal Ab
Isotype : IgG
Purification Method : The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
Conj µgate : Non-conj µgated
Buffer : Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.
Form : Liquid
Stroage : Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
Target Names : CHEK2
Research Areas : Epigenetics and Nuclear Signaling;Cancer

Volume : 100 µL
Clone Number :
Aliases : CDS 1 antibody; Cds1 antibody; Cds1 homolog antibody; Checkpoint kinase 2 antibody; Checkpoint like protein CHK2 antibody; CHEK 2 antibody; Chek2 antibody; Chk 2 antibody; CHK2 checkpoint homolog (S. pombe) antibody; CHK2 checkpoint homolog antibody; CHK2_HUMAN antibody; hCds1 antibody; HuCds 1 antibody; LFS 2 antibody; LFS2 antibody; PP1425 antibody; RAD 53 antibody; RAD53 antibody; Rad53 homolog antibody; Serine/threonine protein kinase Chk2 antibody; Serine/threonine-protein kinase Chk2 antibody
Product Type : polyclonal Ab Antibody
Immunogen Species : Homo sapiens (Human)
UniProt ID : O96017
Immunogen : SyntheVolumed non-phosphopeptide derived from Human Chk2 around the phosphorylation site of threonine 68.
Raised in : Rabbit
Species Reactivity : Human, Mouse, Rat
Tested Applications : ELISA, WB, IHC; WB : 1 : 500-1 : 3000, IHC : 1 : 50-1 : 100
Background : Serine/threonine-protein kinase which is required for checkpoint-mediated cell cycle arrest, activation of DNA repair and apoptosis in response to the presence of DNA double-strand breaks. May also negatively reg µLate cell cycle progression during unperturbed cell cycles. Following activation, phosphorylates numerous effectors preferentially at the consensus sequence [L-X-R-X-X-S/T]. Reg µLates cell cycle checkpoint arrest thro µgh phosphorylation of CDC25A, CDC25B and CDC25C, inhibiting their activity. Inhibition of CDC25 phosphatase activity leads to increased inhibitory tyrosine phosphorylation of CDK-cyclin complexes and blocks cell cycle progression. May also phosphorylate NEK6 which is involved in G2/M cell cycle arrest. Reg µLates DNA repair thro µgh phosphorylation of BRCA2, enhancing the association of RAD51 with chromatin which promotes DNA repair by homologous recombination. Also stim µLates the transcription of genes involved in DNA repair (including BRCA2) thro µgh the phosphorylation and activation of the transcription factor FOXM1. Reg µLates apoptosis thro µgh the phosphorylation of p53/TP53, MDM4 and PML. Phosphorylation of p53/TP53 at 'Ser-20' by CHEK2 may alleviate inhibition by MDM2, leading to accum µLation of active p53/TP53. Phosphorylation of MDM4 may also reduce degradation of p53/TP53. Also controls the transcription of pro-apoptotic genes thro µgh phosphorylation of the transcription factor E2F1. Tumor suppressor, it may also have a DNA damage-independent function in mitotic spindle assembly by phosphorylating BRCA1. Its absence may be a cause of the chromosomal instability observed in some cancer cells.

Bhoumik A, et al. (2005) Mol Cell; 18(5) : 577-87.
Gorgo µLis VG, et al. (2005) Nature; 434(7035) : 907-13.
Falck J, et al. (2005) Nature; 434(7033) : 605-11.
Jin ZH, et al. (2005) Oncogene; 24(12) : 1973-81.
Li J, et al. (2005) J Biol Chem; 280(12) : 12041-50.
Clonality : polyclonal Ab
Isotype : IgG
Purification Method : The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
Conj µgate : Non-conj µgated
Buffer : Rabbit IgG in phosphate buffered saline (without Mg2+ and Ca2+), pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol.
Form : liquid
Stroage : Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
Target Names : CHEK2
Research Areas : Epigenetics and Nuclear Signaling;Cancer

Volume : 100 µL
Clone Number :
Aliases : CDS 1 antibody; Cds1 antibody; Cds1 homolog antibody; Checkpoint kinase 2 antibody; Checkpoint like protein CHK2 antibody; CHEK 2 antibody; Chek2 antibody; Chk 2 antibody; CHK2 checkpoint homolog (S. pombe) antibody; CHK2 checkpoint homolog antibody; CHK2_HUMAN antibody; hCds1 antibody; HuCds 1 antibody; LFS 2 antibody; LFS2 antibody; PP1425 antibody; RAD 53 antibody; RAD53 antibody; Rad53 homolog antibody; Serine/threonine protein kinase Chk2 antibody; Serine/threonine-protein kinase Chk2 antibody
Product Type : polyclonal Ab Antibody
Immunogen Species : Homo sapiens (Human)
UniProt ID : O96017
Immunogen : Peptide sequence around aa. 514~518(Q-P-S-T-S) derived from Human Chk2.
Raised in : Rabbit
Species Reactivity : Human
Tested Applications : ELISA, WB; WB : 1 : 500-1 : 1000
Background :
The BRCA1-BARD1 heterodimer coordinates a diverse range of cell µLar pathways such as DNA damage repair, ubiquitination and transcriptional reg µLation to maintain genomic stability. Acts by mediating ubiquitin E3 ligase activity that is required for its tumor suppressor function. Plays a central role in DNA repair by facilitating cell µLar response to DNA repair. Required for appropriate cell cycle arrests after ionizing irradiation in both the S-phase and the G2 phase of the cell cycle. Involved in transcriptional reg µLation of P21 in response to DNA damage. Required for FANCD2 targeting to sites of DNA damage. May function as a transcriptional reg µLator. Inhibits lipid synthesis by binding to inactive phosphorylated ACACA and preventing its dephosphorylation

Melchionna, R. et al. (2000) Nat. Cell Biol. 2, 762-765.
Ahn, J.Y. et al. (2000) Cancer Res. 60, 5934-5936.
Lee, C.H. and Chung, J.H. (2001) J. Biol. Chem. 276, 30537-30541
Clonality : polyclonal Ab
Isotype : IgG
Purification Method : Antibodies were produced by immunizing rabbits with synthetic peptide and KLH conj µgates. Antibodies were purified by affinity-chromatography using epitope-specific peptide.
Conj µgate : Non-conj µgated
Buffer : Supplied at 1.0mg/mL in phosphate buffered saline (without Mg2+ and Ca2+), pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol.
Form : liquid
Stroage : Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
Target Names : CHEK2
Research Areas : Epigenetics and Nuclear Signaling;Cancer

Volume : 50 µg
Clone Number :
Aliases : C85740 antibody; Cell cycle checkpoint kinase antibody; Checkpoint ; S. pombe; homolog of; 1 antibody; Checkpoint kinase 1 antibody; Checkpoint kinase 1 homolog (S. pombe) antibody; CHEK 1 antibody; Chek1 antibody; Chk 1 antibody; Chk1 antibody; CHK1 checkpoint homolog (S. pombe) antibody; CHK1_HUMAN antibody; EC 2.7.11.1 antibody; rad27 antibody; Serine/threonine protein kinase Chk1 antibody; Serine/threonine-protein kinase CHK1 antibody; STT3; subunit of the oligosaccharyltransferase complex; homolog A (S. cerevisiae) antibody
Product Type : polyclonal Ab Antibody
Immunogen Species : Homo sapiens (Human)
UniProt ID : O14757
Immunogen : Recombinant Human Serine/threonine-protein kinase Chk1 protein (258-370AA)
Raised in : Rabbit
Species Reactivity : Human
Tested Applications : ELISA
Background : Serine/threonine-protein kinase which is required for checkpoint-mediated cell cycle arrest and activation of DNA repair in response to the presence of DNA damage or unreplicated DNA. May also negatively reg µLate cell cycle progression during unperturbed cell cycles. This reg µLation is achieved by a number of mechanisms that together help to preserve the integrity of the genome. Recognizes the substrate consensus sequence [R-X-X-S/T]. Binds to and phosphorylates CDC25A, CDC25B and CDC25C. Phosphorylation of CDC25A at \'Ser-178\' and \'Thr-507\' and phosphorylation of CDC25C at \'Ser-216\' creates binding sites for 14-3-3 proteins which inhibit CDC25A and CDC25C. Phosphorylation of CDC25A at \'Ser-76\', \'Ser-124\', \'Ser-178\', \'Ser-279\' and \'Ser-293\' promotes proteolysis of CDC25A. Phosphorylation of CDC25A at \'Ser-76\' primes the protein for subsequent phosphorylation at \'Ser-79\', \'Ser-82\' and \'Ser-88\' by NEK11 which is required for polyubiquitination and degradation of CDCD25A. Inhibition of CDC25 leads to increased inhibitory tyrosine phosphorylation of CDK-cyclin complexes and blocks cell cycle progression. Also phosphorylates NEK6. Binds to and phosphorylates RAD51 at \'Thr-309\', which promotes the release of RAD51 from BRCA2 and enhances the association of RAD51 with chromatin, thereby promoting DNA repair by homologous recombination. Phosphorylates m µLtiple sites within the C-terminus of TP53, which promotes activation of TP53 by acetylation and promotes cell cycle arrest and suppression of cell µLar proliferation. Also promotes repair of DNA cross-links thro µgh phosphorylation of FANCE. Binds to and phosphorylates TLK1 at \'Ser-743\', which prevents the TLK1-dependent phosphorylation of the chromatin assembly factor ASF1A. This may enhance chromatin assembly both in the presence or absence of DNA damage. May also play a role in replication fork maintenance thro µgh reg µLation of PCNA. May reg µLate the transcription of genes that reg µLate cell-cycle progression thro µgh the phosphorylation of histones. Phosphorylates histone H3.1 (to form H3T11ph), which leads to epigenetic inhibition of a subset of genes. May also phosphorylate RB1 to promote its interaction with the E2F family of transcription factors and subsequent cell cycle arrest.
Clonality : polyclonal Ab
Isotype : IgG
Purification Method : >95%, Protein G purified
Conj µgate : HRP
Buffer : Preservative : 0.03% Proclin 300
Constituents : 50% Glycerol, 0.01M PBS, PH 7.4
Form : Liquid
Stroage : Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
Target Names : CHEK1
Research Areas : Epigenetics and Nuclear Signaling; Cancer

Volume : 50 µg
Clone Number :
Aliases : C85740 antibody; Cell cycle checkpoint kinase antibody; Checkpoint ; S. pombe; homolog of; 1 antibody; Checkpoint kinase 1 antibody; Checkpoint kinase 1 homolog (S. pombe) antibody; CHEK 1 antibody; Chek1 antibody; Chk 1 antibody; Chk1 antibody; CHK1 checkpoint homolog (S. pombe) antibody; CHK1_HUMAN antibody; EC 2.7.11.1 antibody; rad27 antibody; Serine/threonine protein kinase Chk1 antibody; Serine/threonine-protein kinase CHK1 antibody; STT3; subunit of the oligosaccharyltransferase complex; homolog A (S. cerevisiae) antibody
Product Type : polyclonal Ab Antibody
Immunogen Species : Homo sapiens (Human)
UniProt ID : O14757
Immunogen : Recombinant Human Serine/threonine-protein kinase Chk1 protein (258-370AA)
Raised in : Rabbit
Species Reactivity : Human
Tested Applications :
Background : Serine/threonine-protein kinase which is required for checkpoint-mediated cell cycle arrest and activation of DNA repair in response to the presence of DNA damage or unreplicated DNA. May also negatively reg µLate cell cycle progression during unperturbed cell cycles. This reg µLation is achieved by a number of mechanisms that together help to preserve the integrity of the genome. Recognizes the substrate consensus sequence [R-X-X-S/T]. Binds to and phosphorylates CDC25A, CDC25B and CDC25C. Phosphorylation of CDC25A at \'Ser-178\' and \'Thr-507\' and phosphorylation of CDC25C at \'Ser-216\' creates binding sites for 14-3-3 proteins which inhibit CDC25A and CDC25C. Phosphorylation of CDC25A at \'Ser-76\', \'Ser-124\', \'Ser-178\', \'Ser-279\' and \'Ser-293\' promotes proteolysis of CDC25A. Phosphorylation of CDC25A at \'Ser-76\' primes the protein for subsequent phosphorylation at \'Ser-79\', \'Ser-82\' and \'Ser-88\' by NEK11 which is required for polyubiquitination and degradation of CDCD25A. Inhibition of CDC25 leads to increased inhibitory tyrosine phosphorylation of CDK-cyclin complexes and blocks cell cycle progression. Also phosphorylates NEK6. Binds to and phosphorylates RAD51 at \'Thr-309\', which promotes the release of RAD51 from BRCA2 and enhances the association of RAD51 with chromatin, thereby promoting DNA repair by homologous recombination. Phosphorylates m µLtiple sites within the C-terminus of TP53, which promotes activation of TP53 by acetylation and promotes cell cycle arrest and suppression of cell µLar proliferation. Also promotes repair of DNA cross-links thro µgh phosphorylation of FANCE. Binds to and phosphorylates TLK1 at \'Ser-743\', which prevents the TLK1-dependent phosphorylation of the chromatin assembly factor ASF1A. This may enhance chromatin assembly both in the presence or absence of DNA damage. May also play a role in replication fork maintenance thro µgh reg µLation of PCNA. May reg µLate the transcription of genes that reg µLate cell-cycle progression thro µgh the phosphorylation of histones. Phosphorylates histone H3.1 (to form H3T11ph), which leads to epigenetic inhibition of a subset of genes. May also phosphorylate RB1 to promote its interaction with the E2F family of transcription factors and subsequent cell cycle arrest.
Clonality : polyclonal Ab
Isotype : IgG
Purification Method : >95%, Protein G purified
Conj µgate : FITC
Buffer : Preservative : 0.03% Proclin 300
Constituents : 50% Glycerol, 0.01M PBS, PH 7.4
Form : Liquid
Stroage : Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
Target Names : CHEK1
Research Areas : Epigenetics and Nuclear Signaling; Cancer

Volume : 50 µg
Clone Number :
Aliases : C85740 antibody; Cell cycle checkpoint kinase antibody; Checkpoint ; S. pombe; homolog of; 1 antibody; Checkpoint kinase 1 antibody; Checkpoint kinase 1 homolog (S. pombe) antibody; CHEK 1 antibody; Chek1 antibody; Chk 1 antibody; Chk1 antibody; CHK1 checkpoint homolog (S. pombe) antibody; CHK1_HUMAN antibody; EC 2.7.11.1 antibody; rad27 antibody; Serine/threonine protein kinase Chk1 antibody; Serine/threonine-protein kinase CHK1 antibody; STT3; subunit of the oligosaccharyltransferase complex; homolog A (S. cerevisiae) antibody
Product Type : polyclonal Ab Antibody
Immunogen Species : Homo sapiens (Human)
UniProt ID : O14757
Immunogen : Recombinant Human Serine/threonine-protein kinase Chk1 protein (258-370AA)
Raised in : Rabbit
Species Reactivity : Human
Tested Applications : ELISA
Background : Serine/threonine-protein kinase which is required for checkpoint-mediated cell cycle arrest and activation of DNA repair in response to the presence of DNA damage or unreplicated DNA. May also negatively reg µLate cell cycle progression during unperturbed cell cycles. This reg µLation is achieved by a number of mechanisms that together help to preserve the integrity of the genome. Recognizes the substrate consensus sequence [R-X-X-S/T]. Binds to and phosphorylates CDC25A, CDC25B and CDC25C. Phosphorylation of CDC25A at \'Ser-178\' and \'Thr-507\' and phosphorylation of CDC25C at \'Ser-216\' creates binding sites for 14-3-3 proteins which inhibit CDC25A and CDC25C. Phosphorylation of CDC25A at \'Ser-76\', \'Ser-124\', \'Ser-178\', \'Ser-279\' and \'Ser-293\' promotes proteolysis of CDC25A. Phosphorylation of CDC25A at \'Ser-76\' primes the protein for subsequent phosphorylation at \'Ser-79\', \'Ser-82\' and \'Ser-88\' by NEK11 which is required for polyubiquitination and degradation of CDCD25A. Inhibition of CDC25 leads to increased inhibitory tyrosine phosphorylation of CDK-cyclin complexes and blocks cell cycle progression. Also phosphorylates NEK6. Binds to and phosphorylates RAD51 at \'Thr-309\', which promotes the release of RAD51 from BRCA2 and enhances the association of RAD51 with chromatin, thereby promoting DNA repair by homologous recombination. Phosphorylates m µLtiple sites within the C-terminus of TP53, which promotes activation of TP53 by acetylation and promotes cell cycle arrest and suppression of cell µLar proliferation. Also promotes repair of DNA cross-links thro µgh phosphorylation of FANCE. Binds to and phosphorylates TLK1 at \'Ser-743\', which prevents the TLK1-dependent phosphorylation of the chromatin assembly factor ASF1A. This may enhance chromatin assembly both in the presence or absence of DNA damage. May also play a role in replication fork maintenance thro µgh reg µLation of PCNA. May reg µLate the transcription of genes that reg µLate cell-cycle progression thro µgh the phosphorylation of histones. Phosphorylates histone H3.1 (to form H3T11ph), which leads to epigenetic inhibition of a subset of genes. May also phosphorylate RB1 to promote its interaction with the E2F family of transcription factors and subsequent cell cycle arrest.
Clonality : polyclonal Ab
Isotype : IgG
Purification Method : >95%, Protein G purified
Conj µgate : Biotin
Buffer : Preservative : 0.03% Proclin 300
Constituents : 50% Glycerol, 0.01M PBS, PH 7.4
Form : Liquid
Stroage : Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
Target Names : CHEK1
Research Areas : Epigenetics and Nuclear Signaling; Cancer