Volume : 50 µg
Clone Number :
Aliases : Cytosine 5 methyltransferase 3 like protein antibody; DNA (cytosine 5 ) methyltransferase 3 like antibody; DNA (cytosine-5)-methyltransferase 3-like antibody; DNA cytosine 5 methyltransferase 3 like protein antibody; DNA methyltransferase 3 like protein antibody; DNM3L_HUMAN antibody; Dnmt 3L antibody; Dnmt3l antibody; Human cytosine 5 methyltransferase 3 like protein antibody; MGC1090 antibody
Product Type : polyclonal Ab Antibody
Immunogen Species : Homo sapiens (Human)
UniProt ID : Q9UJW3
Immunogen : Recombinant Human DNA (cytosine-5)-methyltransferase 3-like protein (1-234AA)
Raised in : Rabbit
Species Reactivity : Human
Tested Applications :
Background : Catalytically inactive reg µLatory factor of DNA methyltransferases. It is essential for the function of DNMT3A and DNMT3B. Activates DNMT3A and DNMT3B by binding to their catalytic domain. Accelerates the binding of DNA and AdoMet to the methyltransferases and dissociates from the complex after DNA binding to the methyltransferases. Recognizes unmethylated histone H3 lysine 4 (H3K4) and induces de novo DNA methylation by recruitment or activation of DNMT3.
Clonality : polyclonal Ab
Isotype : IgG
Purification Method : >95%, Protein G purified
Conj µgate : FITC
Buffer : Preservative : 0.03% Proclin 300
Constituents : 50% Glycerol, 0.01M PBS, pH 7.4
Form : Liquid
Stroage : Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
Target Names : DNMT3L
Research Areas : Epigenetics and Nuclear Signaling

Volume : 50 µg
Clone Number :
Aliases : Cytosine 5 methyltransferase 3 like protein antibody; DNA (cytosine 5 ) methyltransferase 3 like antibody; DNA (cytosine-5)-methyltransferase 3-like antibody; DNA cytosine 5 methyltransferase 3 like protein antibody; DNA methyltransferase 3 like protein antibody; DNM3L_HUMAN antibody; Dnmt 3L antibody; Dnmt3l antibody; Human cytosine 5 methyltransferase 3 like protein antibody; MGC1090 antibody
Product Type : polyclonal Ab Antibody
Immunogen Species : Homo sapiens (Human)
UniProt ID : Q9UJW3
Immunogen : Recombinant Human DNA (cytosine-5)-methyltransferase 3-like protein (1-234AA)
Raised in : Rabbit
Species Reactivity : Human
Tested Applications : ELISA
Background : Catalytically inactive reg µLatory factor of DNA methyltransferases. It is essential for the function of DNMT3A and DNMT3B. Activates DNMT3A and DNMT3B by binding to their catalytic domain. Accelerates the binding of DNA and AdoMet to the methyltransferases and dissociates from the complex after DNA binding to the methyltransferases. Recognizes unmethylated histone H3 lysine 4 (H3K4) and induces de novo DNA methylation by recruitment or activation of DNMT3.
Clonality : polyclonal Ab
Isotype : IgG
Purification Method : >95%, Protein G purified
Conj µgate : Biotin
Buffer : Preservative : 0.03% Proclin 300
Constituents : 50% Glycerol, 0.01M PBS, pH 7.4
Form : Liquid
Stroage : Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
Target Names : DNMT3L
Research Areas : Epigenetics and Nuclear Signaling

Volume : 100 µL
Host : Rabbit
Clonality : polyclonal Ab
Isotype : IgG
GeneName : DNMT3L
GeneID : 29947
Uniprot : Q9UJW3
Specificity : DNMT3L Antibody detects endogenous levels of total DNMT3L.
Immunogen : A syntheVolumed peptide derived from human DNMT3L, corresponding to a region within the internal amino acids.
Storage : Rabbit IgG in phosphate buffered saline , pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol.Store at -20 °C.Stable for 12 months from date of receipt.
Reactivity : Human,Mouse
Prediction : Pig,Dog
Application : WB,IHC,IF/ICC,IP,ChIP,ELISA(peptide)
Dilution : WB 1 : 500-1 : 2000, IHC 1 : 50-1 : 200, IF/ICC 1 : 20-1 : 50, IP 1 : 20-1 : 50, CHIP 1 : 20-1 : 50, ELISA(peptide) 1 : 20000-1 : 40000
Conj µgate : Unconj µgated
RRID : AB_2838887
An Introduction to Blocking Peptides : A superior strategy for validation of antibody binding is the use of blocking peptides. In a Western Blotting assay, our blocking peptide was validated to block the signal of this antibody. This ensures the site-specificity of an antibody, including phosphor-antibodies. In the case of the phosphor- antibodies, the antibodies can and will only recognize the phosphorylated target protein at the corresponding site, not the non-phosphorylated target protein or target protein phosphorylated at a different site.
Cat# Blocking Peptide : DF6928-BP
Des# Blocking Peptide : DNMT3L Blocking peptide
Blocking Peptide Price : $549 CAD

Volume : 50 µg
Clone Number :
Aliases : Cytosine 5methyltransferase 3B antibody; DNA antibody; DNA (cytosine 5) methyltransferase 3 beta antibody; DNA (cytosine 5)-methyltransferase 3B antibody; DNA (cytosine-5)-methyltransferase 3B antibody; DNA methyltransferase HsaIIIB antibody; DNA MTase HsaIIIB antibody; DNM3B_HUMAN antibody; Dnmt3b antibody; EC 2.1.1.37 antibody; ICF antibody; ICF1 antibody; M.HsaIIIB antibody; MGC124407 antibody; RP23-89H14.3 antibody
Product Type : polyclonal Ab Antibody
Immunogen Species : Homo sapiens (Human)
UniProt ID : Q9UBC3
Immunogen : Recombinant Human DNA (cytosine-5)-methyltransferase 3B protein (1-100AA)
Raised in : Rabbit
Species Reactivity : Human
Tested Applications : ELISA
Background : Required for genome-wide de novo methylation and is essential for the establishment of DNA methylation patterns during development. DNA methylation is coordinated with methylation of histones. May preferentially methylates nucleosomal DNA within the nucleosome core region. May function as transcriptional co-repressor by associating with CBX4 and independently of DNA methylation. Seems to be involved in gene silencing (By similarity). In association with DNMT1 and via the recruitment of CTCFL/BORIS, involved in activation of BAG1 gene expression by mod µLating dimethylation of promoter histone H3 at H3K4 and H3K9. Isoforms 4 and 5 are probably not functional due to the deletion of two conserved methyltransferase motifs. Function as transcriptional corepressor by associating with ZHX1.
Clonality : polyclonal Ab
Isotype : IgG
Purification Method : >95%, Protein G purified
Conj µgate : HRP
Buffer : Preservative : 0.03% Proclin 300
Constituents : 50% Glycerol, 0.01M PBS, PH 7.4
Form : Liquid
Stroage : Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
Target Names : DNMT3B
Research Areas : Epigenetics and Nuclear Signaling

Volume : 50 µg
Clone Number :
Aliases : Cytosine 5methyltransferase 3B antibody; DNA antibody; DNA (cytosine 5) methyltransferase 3 beta antibody; DNA (cytosine 5)-methyltransferase 3B antibody; DNA (cytosine-5)-methyltransferase 3B antibody; DNA methyltransferase HsaIIIB antibody; DNA MTase HsaIIIB antibody; DNM3B_HUMAN antibody; Dnmt3b antibody; EC 2.1.1.37 antibody; ICF antibody; ICF1 antibody; M.HsaIIIB antibody; MGC124407 antibody; RP23-89H14.3 antibody
Product Type : polyclonal Ab Antibody
Immunogen Species : Homo sapiens (Human)
UniProt ID : Q9UBC3
Immunogen : Recombinant Human DNA (cytosine-5)-methyltransferase 3B protein (1-100AA)
Raised in : Rabbit
Species Reactivity : Human
Tested Applications :
Background : Required for genome-wide de novo methylation and is essential for the establishment of DNA methylation patterns during development. DNA methylation is coordinated with methylation of histones. May preferentially methylates nucleosomal DNA within the nucleosome core region. May function as transcriptional co-repressor by associating with CBX4 and independently of DNA methylation. Seems to be involved in gene silencing (By similarity). In association with DNMT1 and via the recruitment of CTCFL/BORIS, involved in activation of BAG1 gene expression by mod µLating dimethylation of promoter histone H3 at H3K4 and H3K9. Isoforms 4 and 5 are probably not functional due to the deletion of two conserved methyltransferase motifs. Function as transcriptional corepressor by associating with ZHX1.
Clonality : polyclonal Ab
Isotype : IgG
Purification Method : >95%, Protein G purified
Conj µgate : FITC
Buffer : Preservative : 0.03% Proclin 300
Constituents : 50% Glycerol, 0.01M PBS, PH 7.4
Form : Liquid
Stroage : Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
Target Names : DNMT3B
Research Areas : Epigenetics and Nuclear Signaling

Volume : 50 µg
Clone Number :
Aliases : Cytosine 5methyltransferase 3B antibody; DNA antibody; DNA (cytosine 5) methyltransferase 3 beta antibody; DNA (cytosine 5)-methyltransferase 3B antibody; DNA (cytosine-5)-methyltransferase 3B antibody; DNA methyltransferase HsaIIIB antibody; DNA MTase HsaIIIB antibody; DNM3B_HUMAN antibody; Dnmt3b antibody; EC 2.1.1.37 antibody; ICF antibody; ICF1 antibody; M.HsaIIIB antibody; MGC124407 antibody; RP23-89H14.3 antibody
Product Type : polyclonal Ab Antibody
Immunogen Species : Homo sapiens (Human)
UniProt ID : Q9UBC3
Immunogen : Recombinant Human DNA (cytosine-5)-methyltransferase 3B protein (1-100AA)
Raised in : Rabbit
Species Reactivity : Human
Tested Applications : ELISA
Background : Required for genome-wide de novo methylation and is essential for the establishment of DNA methylation patterns during development. DNA methylation is coordinated with methylation of histones. May preferentially methylates nucleosomal DNA within the nucleosome core region. May function as transcriptional co-repressor by associating with CBX4 and independently of DNA methylation. Seems to be involved in gene silencing (By similarity). In association with DNMT1 and via the recruitment of CTCFL/BORIS, involved in activation of BAG1 gene expression by mod µLating dimethylation of promoter histone H3 at H3K4 and H3K9. Isoforms 4 and 5 are probably not functional due to the deletion of two conserved methyltransferase motifs. Function as transcriptional corepressor by associating with ZHX1.
Clonality : polyclonal Ab
Isotype : IgG
Purification Method : >95%, Protein G purified
Conj µgate : Biotin
Buffer : Preservative : 0.03% Proclin 300
Constituents : 50% Glycerol, 0.01M PBS, PH 7.4
Form : Liquid
Stroage : Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
Target Names : DNMT3B
Research Areas : Epigenetics and Nuclear Signaling

Volume : 100 µL
Host : Rabbit
Clonality : polyclonal Ab
Isotype : IgG
GeneName : DNMT3B
GeneID : 1789
Uniprot : Q9UBC3
Specificity : DNMT3B Antibody detects endogenous levels of total DNMT3B.
Immunogen : A syntheVolumed peptide derived from human DNMT3B, corresponding to a region within N-terminal amino acids.
Storage : Rabbit IgG in phosphate buffered saline , pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol.Store at -20 °C.Stable for 12 months from date of receipt.
Reactivity : Human,Mouse
Prediction : Horse,Rabbit
Application : WB,IHC,IF/ICC,ELISA(peptide)
Dilution : WB 1 : 500-1 : 1000, IHC : 1 : 50-1 : 200, IF/ICC 1 : 100-1 : 500, ELISA(peptide) 1 : 20000-1 : 40000
Conj µgate : Unconj µgated
RRID : AB_2835824
An Introduction to Blocking Peptides : A superior strategy for validation of antibody binding is the use of blocking peptides. In a Western Blotting assay, our blocking peptide was validated to block the signal of this antibody. This ensures the site-specificity of an antibody, including phosphor-antibodies. In the case of the phosphor- antibodies, the antibodies can and will only recognize the phosphorylated target protein at the corresponding site, not the non-phosphorylated target protein or target protein phosphorylated at a different site.
Cat# Blocking Peptide : DF3459-BP
Des# Blocking Peptide : DNMT3B Blocking peptide
Blocking Peptide Price : $549 CAD

Volume : 50 µg
Clone Number :
Aliases : DNA (cytosine 5) methyltransferase 3 alpha antibody; DNA (cytosine 5) methyltransferase 3A antibody; DNA (cytosine-5)-methyltransferase 3A antibody; DNA cytosine methyltransferase 3A2 antibody; DNA methyltransferase 3 alpha antibody; DNA methyltransferase 3a antibody; DNA methyltransferase HsaIIIA antibody; DNA MTase HsaIIIA antibody; DNM3A_HUMAN antibody; DNMT 3a antibody; DNMT antibody; Dnmt3a antibody; DNMT3A2 antibody; M.HsaIIIA antibody; MCMT antibody; OTTHUMP00000201149 antibody; TBRS antibody
Product Type : polyclonal Ab Antibody
Immunogen Species : Homo sapiens (Human)
UniProt ID : Q9Y6K1
Immunogen : Recombinant Human DNA (cytosine-5)-methyltransferase 3A protein (680-902AA)
Raised in : Rabbit
Species Reactivity : Human
Tested Applications : ELISA
Background : Required for genome-wide de novo methylation and is essential for the establishment of DNA methylation patterns during development. DNA methylation is coordinated with methylation of histones. It modifies DNA in a non-processive manner and also methylates non-CpG sites. May preferentially methylate DNA linker between 2 nucleosomal cores and is inhibited by histone H1. Plays a role in paternal and maternal imprinting. Required for methylation of most imprinted loci in germ cells. Acts as a transcriptional corepressor for ZNF238. Can actively repress transcription thro µgh the recruitment of HDAC activity
Clonality : polyclonal Ab
Isotype : IgG
Purification Method : >95%, Protein G purified
Conj µgate : HRP
Buffer : Preservative : 0.03% Proclin 300
Constituents : 50% Glycerol, 0.01M PBS, PH 7.4
Form : Liquid
Stroage : Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
Target Names : DNMT3A
Research Areas : Epigenetics and Nuclear Signaling

Volume : 50 µg
Clone Number :
Aliases : DNA (cytosine 5) methyltransferase 3 alpha antibody; DNA (cytosine 5) methyltransferase 3A antibody; DNA (cytosine-5)-methyltransferase 3A antibody; DNA cytosine methyltransferase 3A2 antibody; DNA methyltransferase 3 alpha antibody; DNA methyltransferase 3a antibody; DNA methyltransferase HsaIIIA antibody; DNA MTase HsaIIIA antibody; DNM3A_HUMAN antibody; DNMT 3a antibody; DNMT antibody; Dnmt3a antibody; DNMT3A2 antibody; M.HsaIIIA antibody; MCMT antibody; OTTHUMP00000201149 antibody; TBRS antibody
Product Type : polyclonal Ab Antibody
Immunogen Species : Homo sapiens (Human)
UniProt ID : Q9Y6K1
Immunogen : Recombinant Human DNA (cytosine-5)-methyltransferase 3A protein (680-902AA)
Raised in : Rabbit
Species Reactivity : Human
Tested Applications :
Background : Required for genome-wide de novo methylation and is essential for the establishment of DNA methylation patterns during development. DNA methylation is coordinated with methylation of histones. It modifies DNA in a non-processive manner and also methylates non-CpG sites. May preferentially methylate DNA linker between 2 nucleosomal cores and is inhibited by histone H1. Plays a role in paternal and maternal imprinting. Required for methylation of most imprinted loci in germ cells. Acts as a transcriptional corepressor for ZNF238. Can actively repress transcription thro µgh the recruitment of HDAC activity
Clonality : polyclonal Ab
Isotype : IgG
Purification Method : >95%, Protein G purified
Conj µgate : FITC
Buffer : Preservative : 0.03% Proclin 300
Constituents : 50% Glycerol, 0.01M PBS, PH 7.4
Form : Liquid
Stroage : Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
Target Names : DNMT3A
Research Areas : Epigenetics and Nuclear Signaling

Volume : 50 µg
Clone Number :
Aliases : DNA (cytosine 5) methyltransferase 3 alpha antibody; DNA (cytosine 5) methyltransferase 3A antibody; DNA (cytosine-5)-methyltransferase 3A antibody; DNA cytosine methyltransferase 3A2 antibody; DNA methyltransferase 3 alpha antibody; DNA methyltransferase 3a antibody; DNA methyltransferase HsaIIIA antibody; DNA MTase HsaIIIA antibody; DNM3A_HUMAN antibody; DNMT 3a antibody; DNMT antibody; Dnmt3a antibody; DNMT3A2 antibody; M.HsaIIIA antibody; MCMT antibody; OTTHUMP00000201149 antibody; TBRS antibody
Product Type : polyclonal Ab Antibody
Immunogen Species : Homo sapiens (Human)
UniProt ID : Q9Y6K1
Immunogen : Recombinant Human DNA (cytosine-5)-methyltransferase 3A protein (680-902AA)
Raised in : Rabbit
Species Reactivity : Human
Tested Applications : ELISA
Background : Required for genome-wide de novo methylation and is essential for the establishment of DNA methylation patterns during development. DNA methylation is coordinated with methylation of histones. It modifies DNA in a non-processive manner and also methylates non-CpG sites. May preferentially methylate DNA linker between 2 nucleosomal cores and is inhibited by histone H1. Plays a role in paternal and maternal imprinting. Required for methylation of most imprinted loci in germ cells. Acts as a transcriptional corepressor for ZNF238. Can actively repress transcription thro µgh the recruitment of HDAC activity
Clonality : polyclonal Ab
Isotype : IgG
Purification Method : >95%, Protein G purified
Conj µgate : Biotin
Buffer : Preservative : 0.03% Proclin 300
Constituents : 50% Glycerol, 0.01M PBS, PH 7.4
Form : Liquid
Stroage : Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
Target Names : DNMT3A
Research Areas : Epigenetics and Nuclear Signaling

Volume : 100 µL
Host : Rabbit
Clonality : polyclonal Ab
Isotype : IgG
GeneName : DNMT3A
GeneID : 1788
Uniprot : Q9Y6K1
Specificity : DNMT3A Antibody detects endogenous levels of total DNMT3A.
Immunogen : A syntheVolumed peptide derived from human DNMT3A.
Storage : Rabbit IgG in phosphate buffered saline , pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol.Store at -20 °C.Stable for 12 months from date of receipt.
Reactivity : Human,Mouse,Rat
Prediction :
Application : ELISA(peptide)
Dilution : ELISA(peptide) 1 : 20000-1 : 40000
Conj µgate : Unconj µgated
RRID : AB_2847227
An Introduction to Blocking Peptides : A superior strategy for validation of antibody binding is the use of blocking peptides. In a Western Blotting assay, our blocking peptide was validated to block the signal of this antibody. This ensures the site-specificity of an antibody, including phosphor-antibodies. In the case of the phosphor- antibodies, the antibodies can and will only recognize the phosphorylated target protein at the corresponding site, not the non-phosphorylated target protein or target protein phosphorylated at a different site.
Cat# Blocking Peptide : AF6503-BP
Des# Blocking Peptide : DNMT3A Blocking peptide
Blocking Peptide Price : $549 CAD

Volume : 100 µg
Purification : Immunogen affinity purified
Form : liquid
Purity : 95% as determined by SDS-PAGE
Host : Rabbit
Clonality : polyclonal Ab
Clone ID :
Isotype : IgG
Storage : PBS with 0.02% sodium azide and 50% glycerol pH 7.3,-20? for 12 months(Avoid repeated freeze / thaw cycles.)
Background :
Immunogen : tRNA aspartic acid methyltransferase 1
Aliases : DNA MTase homolog HsaIIP, DNMT2, M.HsaIIP, PuMet, RNMT1 TRDMT1
Observed MW : 43-45 kDa
Uniprot ID : O14717
Reactivity : Human, Mouse, Rat
Application : ELISA, WB
Recommended dilution : WB : 1 : 500-1 : 2000
Gene ID :
Research Area : Epigenetics, Metabolism

Volume : 50 µg
Clone Number :
Aliases : ADCADN antibody; AIM antibody; CXXC finger protein 9 antibody; CXXC-type zinc finger protein 9 antibody; CXXC9 antibody; DNA (cytosine 5 ) methyltransferase 1 antibody; DNA (cytosine-5)-methyltransferase 1 antibody; DNA methyltransferase 1 antibody; DNA methyltransferase HsaI antibody; DNA methyltransferase M.HsaI. antibody; DNA MTase antibody; DNA MTase HsaI antibody; DNMT 1 antibody; DNMT antibody; Dnmt1 antibody; DNMT1_HUMAN antibody; Dnmt1o antibody; FLJ16293 antibody; HSN1E antibody; M.HsaI antibody; MCMT antibody; Met1 antibody; MGC104992 antibody; mMm µL antibody; MommeD2 antibody
Product Type : polyclonal Ab Antibody
Immunogen Species : Homo sapiens (Human)
UniProt ID : P26358
Immunogen : Recombinant Human DNA (cytosine-5)-methyltransferase 1 protein (1288-1632AA)
Raised in : Rabbit
Species Reactivity : Human
Tested Applications : ELISA
Background : Methylates CpG residues. Preferentially methylates hemimethylated DNA. Associates with DNA replication sites in S phase maintaining the methylation pattern in the newly syntheVolumed strand, that is essential for epigenetic inheritance. Associates with chromatin during G2 and M phases to maintain DNA methylation independently of replication. It is responsible for maintaining methylation patterns established in development. DNA methylation is coordinated with methylation of histones. Mediates transcriptional repression by direct binding to HDAC2. In association with DNMT3B and via the recruitment of CTCFL/BORIS, involved in activation of BAG1 gene expression by mod µLating dimethylation of promoter histone H3 at H3K4 and H3K9. Probably forms a corepressor complex required for activated KRAS-mediated promoter hypermethylation and transcriptional silencing of tumor suppressor genes (TSGs) or other tumor-related genes in colorectal cancer (CRC) cells (PubMed : 24623306). Also required to maintain a transcriptionally repressive state of genes in undifferentiated embryonic stem cells (ESCs) (PubMed : 24623306). Associates at promoter regions of tumor suppressor genes (TSGs) leading to their gene silencing (PubMed : 24623306). Promotes tumor growth (PubMed : 24623306).
Clonality : polyclonal Ab
Isotype : IgG
Purification Method : >95%, Protein G purified
Conj µgate : HRP
Buffer : Preservative : 0.03% Proclin 300
Constituents : 50% Glycerol, 0.01M PBS, PH 7.4
Form : Liquid
Stroage : Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
Target Names : DNMT1
Research Areas : Epigenetics and Nuclear Signaling

Volume : 50 µg
Clone Number :
Aliases : ADCADN antibody; AIM antibody; CXXC finger protein 9 antibody; CXXC-type zinc finger protein 9 antibody; CXXC9 antibody; DNA (cytosine 5 ) methyltransferase 1 antibody; DNA (cytosine-5)-methyltransferase 1 antibody; DNA methyltransferase 1 antibody; DNA methyltransferase HsaI antibody; DNA methyltransferase M.HsaI. antibody; DNA MTase antibody; DNA MTase HsaI antibody; DNMT 1 antibody; DNMT antibody; Dnmt1 antibody; DNMT1_HUMAN antibody; Dnmt1o antibody; FLJ16293 antibody; HSN1E antibody; M.HsaI antibody; MCMT antibody; Met1 antibody; MGC104992 antibody; mMm µL antibody; MommeD2 antibody
Product Type : polyclonal Ab Antibody
Immunogen Species : Homo sapiens (Human)
UniProt ID : P26358
Immunogen : Recombinant Human DNA (cytosine-5)-methyltransferase 1 protein (1288-1632AA)
Raised in : Rabbit
Species Reactivity : Human
Tested Applications :
Background : Methylates CpG residues. Preferentially methylates hemimethylated DNA. Associates with DNA replication sites in S phase maintaining the methylation pattern in the newly syntheVolumed strand, that is essential for epigenetic inheritance. Associates with chromatin during G2 and M phases to maintain DNA methylation independently of replication. It is responsible for maintaining methylation patterns established in development. DNA methylation is coordinated with methylation of histones. Mediates transcriptional repression by direct binding to HDAC2. In association with DNMT3B and via the recruitment of CTCFL/BORIS, involved in activation of BAG1 gene expression by mod µLating dimethylation of promoter histone H3 at H3K4 and H3K9. Probably forms a corepressor complex required for activated KRAS-mediated promoter hypermethylation and transcriptional silencing of tumor suppressor genes (TSGs) or other tumor-related genes in colorectal cancer (CRC) cells (PubMed : 24623306). Also required to maintain a transcriptionally repressive state of genes in undifferentiated embryonic stem cells (ESCs) (PubMed : 24623306). Associates at promoter regions of tumor suppressor genes (TSGs) leading to their gene silencing (PubMed : 24623306). Promotes tumor growth (PubMed : 24623306).
Clonality : polyclonal Ab
Isotype : IgG
Purification Method : >95%, Protein G purified
Conj µgate : FITC
Buffer : Preservative : 0.03% Proclin 300
Constituents : 50% Glycerol, 0.01M PBS, PH 7.4
Form : Liquid
Stroage : Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
Target Names : DNMT1
Research Areas : Epigenetics and Nuclear Signaling

Volume : 50 µg
Clone Number :
Aliases : ADCADN antibody; AIM antibody; CXXC finger protein 9 antibody; CXXC-type zinc finger protein 9 antibody; CXXC9 antibody; DNA (cytosine 5 ) methyltransferase 1 antibody; DNA (cytosine-5)-methyltransferase 1 antibody; DNA methyltransferase 1 antibody; DNA methyltransferase HsaI antibody; DNA methyltransferase M.HsaI. antibody; DNA MTase antibody; DNA MTase HsaI antibody; DNMT 1 antibody; DNMT antibody; Dnmt1 antibody; DNMT1_HUMAN antibody; Dnmt1o antibody; FLJ16293 antibody; HSN1E antibody; M.HsaI antibody; MCMT antibody; Met1 antibody; MGC104992 antibody; mMm µL antibody; MommeD2 antibody
Product Type : polyclonal Ab Antibody
Immunogen Species : Homo sapiens (Human)
UniProt ID : P26358
Immunogen : Recombinant Human DNA (cytosine-5)-methyltransferase 1 protein (1288-1632AA)
Raised in : Rabbit
Species Reactivity : Human
Tested Applications : ELISA
Background : Methylates CpG residues. Preferentially methylates hemimethylated DNA. Associates with DNA replication sites in S phase maintaining the methylation pattern in the newly syntheVolumed strand, that is essential for epigenetic inheritance. Associates with chromatin during G2 and M phases to maintain DNA methylation independently of replication. It is responsible for maintaining methylation patterns established in development. DNA methylation is coordinated with methylation of histones. Mediates transcriptional repression by direct binding to HDAC2. In association with DNMT3B and via the recruitment of CTCFL/BORIS, involved in activation of BAG1 gene expression by mod µLating dimethylation of promoter histone H3 at H3K4 and H3K9. Probably forms a corepressor complex required for activated KRAS-mediated promoter hypermethylation and transcriptional silencing of tumor suppressor genes (TSGs) or other tumor-related genes in colorectal cancer (CRC) cells (PubMed : 24623306). Also required to maintain a transcriptionally repressive state of genes in undifferentiated embryonic stem cells (ESCs) (PubMed : 24623306). Associates at promoter regions of tumor suppressor genes (TSGs) leading to their gene silencing (PubMed : 24623306). Promotes tumor growth (PubMed : 24623306).
Clonality : polyclonal Ab
Isotype : IgG
Purification Method : >95%, Protein G purified
Conj µgate : Biotin
Buffer : Preservative : 0.03% Proclin 300
Constituents : 50% Glycerol, 0.01M PBS, PH 7.4
Form : Liquid
Stroage : Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
Target Names : DNMT1
Research Areas : Epigenetics and Nuclear Signaling

Volume : 100 µL
Host : Rabbit
Clonality : polyclonal Ab
Isotype : IgG
GeneName : DNMT1
GeneID : 1786
Uniprot : P26358
Specificity : Dnmt1 Antibody detects endogenous levels of total Dnmt1.
Immunogen : A syntheVolumed peptide derived from human Dnmt1 corresponding to a region within the internal amino acids.
Storage : Rabbit IgG in phosphate buffered saline , pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol.Store at -20 °C.Stable for 12 months from date of receipt.
Reactivity : Human,Mouse,Rat
Prediction : Bovine,Horse,Sheep
Application : WB,IHC,IF/ICC,ELISA(peptide)
Dilution : WB 1 : 500-1 : 2000, IHC 1 : 50-1 : 200, IF/ICC 1 : 100-1 : 400, ELISA(peptide) 1 : 20000-1 : 40000
Conj µgate : Unconj µgated
RRID : AB_2839314
An Introduction to Blocking Peptides : A superior strategy for validation of antibody binding is the use of blocking peptides. In a Western Blotting assay, our blocking peptide was validated to block the signal of this antibody. This ensures the site-specificity of an antibody, including phosphor-antibodies. In the case of the phosphor- antibodies, the antibodies can and will only recognize the phosphorylated target protein at the corresponding site, not the non-phosphorylated target protein or target protein phosphorylated at a different site.
Cat# Blocking Peptide : DF7376-BP
Des# Blocking Peptide : Dnmt1 Blocking peptide
Blocking Peptide Price : $549 CAD

Volume : 100 µg
Purification : Immunogen affinity purified
Form : liquid
Purity : 95% as determined by SDS-PAGE
Host : Rabbit
Clonality : polyclonal Ab
Clone ID :
Isotype : IgG
Storage : PBS with 0.02% sodium azide and 50% glycerol pH 7.3,-20? for 12 months(Avoid repeated freeze / thaw cycles.)
Background : Scaffold protein that links dynamin with actin-reg µLating proteins. May play a role in membrane trafficking between the cell surface and the Golgi(By similarity).
Immunogen : dynamin binding protein
Aliases : DNMBP, dynamin binding protein, KIAA1010, Scaffold protein Tuba, TUBA
Observed MW : 180kd
Uniprot ID : Q6XZF7
Reactivity : Human, Mouse, Rat
Application : ELISA, WB, IP
Recommended dilution : WB : 1 : 500-1 : 3000; IP : 1 : 500-1 : 2000
Gene ID : 23268
Research Area : Neuroscience, Signal Transduction

Volume : 100 µL
Host : Rabbit
Clonality : polyclonal Ab
Isotype : IgG
GeneName : DNM3
GeneID : 26052
Uniprot : Q9UQ16
Specificity : DNM3 Antibody detects endogenous levels of total DNM3.
Immunogen : A syntheVolumed peptide derived from human DNM3, corresponding to a region within C-terminal amino acids.
Storage : Rabbit IgG in phosphate buffered saline , pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol.Store at -20 °C.Stable for 12 months from date of receipt.
Reactivity : Human,Mouse,Rat
Prediction : Pig,Rabbit,Dog
Application : WB
Dilution : WB 1 : 500-1 : 2000
Conj µgate : Unconj µgated
RRID : AB_2845561
An Introduction to Blocking Peptides : A superior strategy for validation of antibody binding is the use of blocking peptides. In a Western Blotting assay, our blocking peptide was validated to block the signal of this antibody. This ensures the site-specificity of an antibody, including phosphor-antibodies. In the case of the phosphor- antibodies, the antibodies can and will only recognize the phosphorylated target protein at the corresponding site, not the non-phosphorylated target protein or target protein phosphorylated at a different site.
Cat# Blocking Peptide : DF12599-BP
Des# Blocking Peptide : DNM3 Blocking peptide
Blocking Peptide Price : $549 CAD

Volume : 50 µL
Clone Number :
Aliases : Dynamin-2 (EC 3.6.5.5), DNM2, DYN2
Product Type : polyclonal Ab Antibody
Immunogen Species : Homo sapiens (Human)
UniProt ID : P50570
Immunogen : Recombinant Human Dynamin-2 protein (640-1119aa)
Raised in : Rabbit
Species Reactivity : Human
Tested Applications : ELISA
Background : Microtub µLe-associated force-producing protein involved in producing microtub µLe bundles and able to bind and hydrolyze GTP. Plays a role in the reg µLation of neuron morphology, axon growth and formation of neuronal growth cones (By similarity). Plays an important role in vesic µLar trafficking processes, in partic µLar endocytosis. Involved in cytokinesis (PubMed : 12498685). Reg µLates maturation of apoptotic cell corpse-containing phagosomes by recruiting PIK3C3 to the phagosome membrane (By similarity).
Clonality : polyclonal Ab
Isotype : IgG
Purification Method : >95%, Protein G purified
Conj µgate : HRP
Buffer : Preservative : 0.03% Proclin 300
Constituents : 50% Glycerol, 0.01M PBS, pH 7.4
Form : Liquid
Stroage : Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
Target Names : DNM2
Research Areas : Signal Transduction

Volume : 50 µL
Clone Number :
Aliases : Dynamin-2 (EC 3.6.5.5), DNM2, DYN2
Product Type : polyclonal Ab Antibody
Immunogen Species : Homo sapiens (Human)
UniProt ID : P50570
Immunogen : Recombinant Human Dynamin-2 protein (640-1119aa)
Raised in : Rabbit
Species Reactivity : Human
Tested Applications :
Background : Microtub µLe-associated force-producing protein involved in producing microtub µLe bundles and able to bind and hydrolyze GTP. Plays a role in the reg µLation of neuron morphology, axon growth and formation of neuronal growth cones (By similarity). Plays an important role in vesic µLar trafficking processes, in partic µLar endocytosis. Involved in cytokinesis (PubMed : 12498685). Reg µLates maturation of apoptotic cell corpse-containing phagosomes by recruiting PIK3C3 to the phagosome membrane (By similarity).
Clonality : polyclonal Ab
Isotype : IgG
Purification Method : >95%, Protein G purified
Conj µgate : FITC
Buffer : Preservative : 0.03% Proclin 300
Constituents : 50% Glycerol, 0.01M PBS, pH 7.4
Form : Liquid
Stroage : Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
Target Names : DNM2
Research Areas : Signal Transduction

Volume : 50 µL
Clone Number :
Aliases : Dynamin-2 (EC 3.6.5.5), DNM2, DYN2
Product Type : polyclonal Ab Antibody
Immunogen Species : Homo sapiens (Human)
UniProt ID : P50570
Immunogen : Recombinant Human Dynamin-2 protein (640-1119aa)
Raised in : Rabbit
Species Reactivity : Human
Tested Applications : ELISA
Background : Microtub µLe-associated force-producing protein involved in producing microtub µLe bundles and able to bind and hydrolyze GTP. Plays a role in the reg µLation of neuron morphology, axon growth and formation of neuronal growth cones (By similarity). Plays an important role in vesic µLar trafficking processes, in partic µLar endocytosis. Involved in cytokinesis (PubMed : 12498685). Reg µLates maturation of apoptotic cell corpse-containing phagosomes by recruiting PIK3C3 to the phagosome membrane (By similarity).
Clonality : polyclonal Ab
Isotype : IgG
Purification Method : >95%, Protein G purified
Conj µgate : Biotin
Buffer : Preservative : 0.03% Proclin 300
Constituents : 50% Glycerol, 0.01M PBS, pH 7.4
Form : Liquid
Stroage : Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
Target Names : DNM2
Research Areas : Signal Transduction

Volume : 100 µg
Purification : Immunogen affinity purified
Form : liquid
Purity : 95% as determined by SDS-PAGE
Host : Rabbit
Clonality : polyclonal Ab
Clone ID :
Isotype : IgG
Storage : PBS with 0.02% sodium azide and 50% glycerol pH 7.3,-20? for 12 months(Avoid repeated freeze / thaw cycles.)
Background : Microtub µLe-associated force-producing protein involved in producing microtub µLe bundles and able to bind and hydrolyze GTP. Plays a role in the reg µLation of neuron morphology, axon growth and formation of neuronal growth cones(By similarity). Plays an important role in vesic µLar trafficking processes, in partic µLar endocytosis. Involved in cytokinesis(PubMed : 12498685). Reg µLates maturation of apoptotic cell corpse-containing phagosomes by recruiting PIK3C3 to the phagosome membrane(By similarity).
Immunogen : dynamin 2
Aliases : DYN2
Observed MW : 100kd
Uniprot ID : P50570
Reactivity : Human, Mouse, Rat
Application : ELISA, WB
Recommended dilution : WB : 1 : 500-1 : 2000
Gene ID : 1785
Research Area : Neuroscience, Signal Transduction, Metabolism

Volume : 50 µg
Clone Number :
Aliases : DLP1 antibody; dnm1l antibody; DNM1L_HUMAN antibody; Dnm1p/Vps1p-like protein antibody; dnml1 antibody; DRP1 antibody; DVLP antibody; Dymple antibody; Dynamin 1 like antibody; Dynamin family member proline-rich carboxyl-terminal domain less antibody; Dynamin like protein antibody; Dynamin related protein 1 antibody; Dynamin-1-like protein antibody; Dynamin-like protein 4 antibody; Dynamin-like protein antibody; Dynamin-like protein IV antibody; Dynamin-related protein 1 antibody; DYNIV 11 antibody; EMPF antibody; EMPF1 antibody; FLJ41912 antibody; HdynIV antibody; VPS1 antibody
Product Type : polyclonal Ab Antibody
Immunogen Species : Homo sapiens (Human)
UniProt ID : O00429
Immunogen : Recombinant Human Dynamin-1-like protein (496-710AA)
Raised in : Rabbit
Species Reactivity : Human
Tested Applications : ELISA
Background : Functions in mitochondrial and peroxisomal division. Mediates membrane fission thro µgh oligomerization into membrane-associated tub µLar structures that wrap around the scission site to constrict and sever the mitochondrial membrane thro µgh a GTP hydrolysis-dependent mechanism. Thro µgh its function in mitochondrial division, ensures the survival of at least some types of postmitotic neurons, including Purkinje cells, by suppressing oxidative damage. Required for normal brain development, including that of cerebellum. Facilitates developmentally reg µLated apoptosis during neural tube formation. Required for a normal rate of cytochrome c release and caspase activation during apoptosis; this requirement may depend upon the cell type and the physiological apoptotic cues. Also required for mitochondrial fission during mitosis. Required for formation of endocytic vesicles. Proposed to reg µLate synaptic vesicle membrane dynamics thro µgh association with BCL2L1 isoform Bcl-X(L) which stim µLates its GTPase activity in synaptic vesicles; the function may require its recruitment by MFF to clathrin-containing vesicles. Required for programmed necrosis execution.
Clonality : polyclonal Ab
Isotype : IgG
Purification Method : >95%, Protein G purified
Conj µgate : HRP
Buffer : Preservative : 0.03% Proclin 300
Constituents : 50% Glycerol, 0.01M PBS, PH 7.4
Form : Liquid
Stroage : Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
Target Names : DNM1L
Research Areas : Neuroscience; Cancer; Cell biology; Metabolism; Signal transduction

Volume : 50 µg
Clone Number :
Aliases : DLP1 antibody; dnm1l antibody; DNM1L_HUMAN antibody; Dnm1p/Vps1p-like protein antibody; dnml1 antibody; DRP1 antibody; DVLP antibody; Dymple antibody; Dynamin 1 like antibody; Dynamin family member proline-rich carboxyl-terminal domain less antibody; Dynamin like protein antibody; Dynamin related protein 1 antibody; Dynamin-1-like protein antibody; Dynamin-like protein 4 antibody; Dynamin-like protein antibody; Dynamin-like protein IV antibody; Dynamin-related protein 1 antibody; DYNIV 11 antibody; EMPF antibody; EMPF1 antibody; FLJ41912 antibody; HdynIV antibody; VPS1 antibody
Product Type : polyclonal Ab Antibody
Immunogen Species : Homo sapiens (Human)
UniProt ID : O00429
Immunogen : Recombinant Human Dynamin-1-like protein (496-710AA)
Raised in : Rabbit
Species Reactivity : Human
Tested Applications :
Background : Functions in mitochondrial and peroxisomal division. Mediates membrane fission thro µgh oligomerization into membrane-associated tub µLar structures that wrap around the scission site to constrict and sever the mitochondrial membrane thro µgh a GTP hydrolysis-dependent mechanism. Thro µgh its function in mitochondrial division, ensures the survival of at least some types of postmitotic neurons, including Purkinje cells, by suppressing oxidative damage. Required for normal brain development, including that of cerebellum. Facilitates developmentally reg µLated apoptosis during neural tube formation. Required for a normal rate of cytochrome c release and caspase activation during apoptosis; this requirement may depend upon the cell type and the physiological apoptotic cues. Also required for mitochondrial fission during mitosis. Required for formation of endocytic vesicles. Proposed to reg µLate synaptic vesicle membrane dynamics thro µgh association with BCL2L1 isoform Bcl-X(L) which stim µLates its GTPase activity in synaptic vesicles; the function may require its recruitment by MFF to clathrin-containing vesicles. Required for programmed necrosis execution.
Clonality : polyclonal Ab
Isotype : IgG
Purification Method : >95%, Protein G purified
Conj µgate : FITC
Buffer : Preservative : 0.03% Proclin 300
Constituents : 50% Glycerol, 0.01M PBS, PH 7.4
Form : Liquid
Stroage : Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
Target Names : DNM1L
Research Areas : Neuroscience; Cancer; Cell biology; Metabolism; Signal transduction

Volume : 50 µg
Clone Number :
Aliases : DLP1 antibody; dnm1l antibody; DNM1L_HUMAN antibody; Dnm1p/Vps1p-like protein antibody; dnml1 antibody; DRP1 antibody; DVLP antibody; Dymple antibody; Dynamin 1 like antibody; Dynamin family member proline-rich carboxyl-terminal domain less antibody; Dynamin like protein antibody; Dynamin related protein 1 antibody; Dynamin-1-like protein antibody; Dynamin-like protein 4 antibody; Dynamin-like protein antibody; Dynamin-like protein IV antibody; Dynamin-related protein 1 antibody; DYNIV 11 antibody; EMPF antibody; EMPF1 antibody; FLJ41912 antibody; HdynIV antibody; VPS1 antibody
Product Type : polyclonal Ab Antibody
Immunogen Species : Homo sapiens (Human)
UniProt ID : O00429
Immunogen : Recombinant Human Dynamin-1-like protein (496-710AA)
Raised in : Rabbit
Species Reactivity : Human
Tested Applications : ELISA
Background : Functions in mitochondrial and peroxisomal division. Mediates membrane fission thro µgh oligomerization into membrane-associated tub µLar structures that wrap around the scission site to constrict and sever the mitochondrial membrane thro µgh a GTP hydrolysis-dependent mechanism. Thro µgh its function in mitochondrial division, ensures the survival of at least some types of postmitotic neurons, including Purkinje cells, by suppressing oxidative damage. Required for normal brain development, including that of cerebellum. Facilitates developmentally reg µLated apoptosis during neural tube formation. Required for a normal rate of cytochrome c release and caspase activation during apoptosis; this requirement may depend upon the cell type and the physiological apoptotic cues. Also required for mitochondrial fission during mitosis. Required for formation of endocytic vesicles. Proposed to reg µLate synaptic vesicle membrane dynamics thro µgh association with BCL2L1 isoform Bcl-X(L) which stim µLates its GTPase activity in synaptic vesicles; the function may require its recruitment by MFF to clathrin-containing vesicles. Required for programmed necrosis execution.
Clonality : polyclonal Ab
Isotype : IgG
Purification Method : >95%, Protein G purified
Conj µgate : Biotin
Buffer : Preservative : 0.03% Proclin 300
Constituents : 50% Glycerol, 0.01M PBS, PH 7.4
Form : Liquid
Stroage : Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
Target Names : DNM1L
Research Areas : Neuroscience; Cancer; Cell biology; Metabolism; Signal transduction

Volume : 50 µg
Clone Number :
Aliases : DLP1 antibody; dnm1l antibody; DNM1L_HUMAN antibody; Dnm1p/Vps1p-like protein antibody; dnml1 antibody; DRP1 antibody; DVLP antibody; Dymple antibody; Dynamin 1 like antibody; Dynamin family member proline-rich carboxyl-terminal domain less antibody; Dynamin like protein antibody; Dynamin related protein 1 antibody; Dynamin-1-like protein antibody; Dynamin-like protein 4 antibody; Dynamin-like protein antibody; Dynamin-like protein IV antibody; Dynamin-related protein 1 antibody; DYNIV 11 antibody; EMPF antibody; EMPF1 antibody; FLJ41912 antibody; HdynIV antibody; VPS1 antibody
Product Type : polyclonal Ab Antibody
Immunogen Species : Homo sapiens (Human)
UniProt ID : O00429
Immunogen : SyntheVolumed peptide derived from Human DRP1 around the non-phosphorylation site of S637.
Raised in : Rabbit
Species Reactivity : Human, Mouse, Rat
Tested Applications : WB, IHC, ELISA; WB : 1 : 500-1 : 2000, IHC : 1 : 100-1 : 300, ELISA : 1 : 10000
Background :
Clonality : polyclonal Ab
Isotype : IgG
Purification Method : The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
Conj µgate : Non-conj µgated
Buffer : Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.
Form : Liquid
Stroage : Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
Target Names : DNM1L
Research Areas : Neuroscience?Cancer;Cell biology;Metabolism;Signal transduction

Volume : 100 µL
Clone Number :
Aliases : DLP1 antibody; dnm1l antibody; DNM1L_HUMAN antibody; Dnm1p/Vps1p-like protein antibody; dnml1 antibody; DRP1 antibody; DVLP antibody; Dymple antibody; Dynamin 1 like antibody; Dynamin family member proline-rich carboxyl-terminal domain less antibody; Dynamin like protein antibody; Dynamin related protein 1 antibody; Dynamin-1-like protein antibody; Dynamin-like protein 4 antibody; Dynamin-like protein antibody; Dynamin-like protein IV antibody; Dynamin-related protein 1 antibody; DYNIV 11 antibody; EMPF antibody; EMPF1 antibody; FLJ41912 antibody; HdynIV antibody; VPS1 antibody
Product Type : polyclonal Ab Antibody
Immunogen Species : Homo sapiens (Human)
UniProt ID : O00429
Immunogen : SyntheVolumed peptide derived from C-terminal of Human DNM1L.
Raised in : Rabbit
Species Reactivity : Human, Mouse, Rat
Tested Applications : ELISA, WB; WB : 1 : 500-1 : 3000
Background : Functions in mitochondrial and peroxisomal division. Mediates membrane fission thro µgh oligomerization into membrane-associated tub µLar structures that wrap around the scission site to constrict and sever the mitochondrial membrane thro µgh a GTP hydrolysis-dependent mechanism. Thro µgh its function in mitochondrial division, ensures the survival of at least some types of postmitotic neurons, including Purkinje cells, by suppressing oxidative damage. Required for normal brain development, including that of cerebellum. Facilitates developmentally reg µLated apoptosis during neural tube formation. Required for a normal rate of cytochrome c release and caspase activation during apoptosis; this requirement may depend upon the cell type and the physiological apoptotic cues. Also required for mitochondrial fission during mitosis. Required for formation of endocytic vesicles. Proposed to reg µLate synaptic vesicle membrane dynamics thro µgh association with BCL2L1 isoform Bcl-X(L)which stim µLates its GTPase activity in synaptic vesicles; the function may require its recruitment by MFF to clathrin-containing vesicles. Required for programmed necrosis execution. Isoform 1 and isoform 4 inhibit peroxisomal division when overexpressed.

Shin H.-W., J. Biochem. 122 : 525-530(1997).
Hong Y.-R., Biochem. Biophys. Res. Commun. 249 : 697-703(1998).
Imoto M., J. Cell Sci. 111 : 1341-1349(1998).

Clonality : polyclonal Ab
Isotype : IgG
Purification Method : The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
Conj µgate : Non-conj µgated
Buffer : Rabbit IgG in phosphate buffered saline (without Mg2+ and Ca2+), pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol.
Form : liquid
Stroage : Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
Target Names : DNM1L
Research Areas : Neuroscience?Cancer;Cell biology;Metabolism;Signal transduction

Volume : 50 µg
Clone Number :
Aliases : B dynamin antibody; D100 antibody; DNM 1 antibody; DNM antibody; DNM1 antibody; DYN1_HUMAN antibody; Dynamin antibody; Dynamin-1 antibody; Dynamin1 antibody
Product Type : polyclonal Ab Antibody
Immunogen Species : Homo sapiens (Human)
UniProt ID : Q05193
Immunogen : Recombinant Human Dynamin-1 protein (2-245AA)
Raised in : Rabbit
Species Reactivity : Human
Tested Applications : ELISA
Background : Microtub µLe-associated force-producing protein involved in producing microtub µLe bundles and able to bind and hydrolyze GTP. Most probably involved in vesic µLar trafficking processes. Involved in receptor-mediated endocytosis.
Clonality : polyclonal Ab
Isotype : IgG
Purification Method : >95%, Protein G purified
Conj µgate : HRP
Buffer : Preservative : 0.03% Proclin 300
Constituents : 50% Glycerol, 0.01M PBS, PH 7.4
Form : Liquid
Stroage : Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
Target Names : DNM1
Research Areas : Neuroscience; Signal transduction

Volume : 50 µg
Clone Number :
Aliases : B dynamin antibody; D100 antibody; DNM 1 antibody; DNM antibody; DNM1 antibody; DYN1_HUMAN antibody; Dynamin antibody; Dynamin-1 antibody; Dynamin1 antibody
Product Type : polyclonal Ab Antibody
Immunogen Species : Homo sapiens (Human)
UniProt ID : Q05193
Immunogen : Recombinant Human Dynamin-1 protein (2-245AA)
Raised in : Rabbit
Species Reactivity : Human
Tested Applications :
Background : Microtub µLe-associated force-producing protein involved in producing microtub µLe bundles and able to bind and hydrolyze GTP. Most probably involved in vesic µLar trafficking processes. Involved in receptor-mediated endocytosis.
Clonality : polyclonal Ab
Isotype : IgG
Purification Method : >95%, Protein G purified
Conj µgate : FITC
Buffer : Preservative : 0.03% Proclin 300
Constituents : 50% Glycerol, 0.01M PBS, PH 7.4
Form : Liquid
Stroage : Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
Target Names : DNM1
Research Areas : Neuroscience; Signal transduction

Volume : 50 µg
Clone Number :
Aliases : B dynamin antibody; D100 antibody; DNM 1 antibody; DNM antibody; DNM1 antibody; DYN1_HUMAN antibody; Dynamin antibody; Dynamin-1 antibody; Dynamin1 antibody
Product Type : polyclonal Ab Antibody
Immunogen Species : Homo sapiens (Human)
UniProt ID : Q05193
Immunogen : Recombinant Human Dynamin-1 protein (2-245AA)
Raised in : Rabbit
Species Reactivity : Human
Tested Applications : ELISA
Background : Microtub µLe-associated force-producing protein involved in producing microtub µLe bundles and able to bind and hydrolyze GTP. Most probably involved in vesic µLar trafficking processes. Involved in receptor-mediated endocytosis.
Clonality : polyclonal Ab
Isotype : IgG
Purification Method : >95%, Protein G purified
Conj µgate : Biotin
Buffer : Preservative : 0.03% Proclin 300
Constituents : 50% Glycerol, 0.01M PBS, PH 7.4
Form : Liquid
Stroage : Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
Target Names : DNM1
Research Areas : Neuroscience; Signal transduction

Volume : 50 µg
Clone Number :
Aliases : B dynamin antibody; D100 antibody; DNM 1 antibody; DNM antibody; DNM1 antibody; DYN1_HUMAN antibody; Dynamin antibody; Dynamin-1 antibody; Dynamin1 antibody
Product Type : polyclonal Ab Antibody
Immunogen Species : Homo sapiens (Human)
UniProt ID : Q05193
Immunogen : SyntheVolumed peptide derived from Human Dynamin I around the non-phosphorylation site of S774.
Raised in : Rabbit
Species Reactivity : Human, Mouse, Rat
Tested Applications : WB, IHC, ELISA; WB : 1 : 500-1 : 2000, IHC : 1 : 100-1 : 300, ELISA : 1 : 40000
Background :
Clonality : polyclonal Ab
Isotype : IgG
Purification Method : The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
Conj µgate : Non-conj µgated
Buffer : Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.
Form : Liquid
Stroage : Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
Target Names : DNM1
Research Areas : Neuroscience;Signal transduction

Volume : 50 µL
Clone Number :
Aliases : bet antibody; Brain EGF repeat-containing transmembrane protein antibody; Bret antibody; Delta and Notch-like epidermal growth factor-related receptor antibody; Delta notch like EGF repeat containing transmembrane antibody; Delta/notch like EGF repeat containing antibody; Delta/notch-like EGF-related receptor antibody; Dner antibody; DNER_HUMAN antibody; PRO299 antibody; Transmembrane protein Bet antibody; UNQ26 antibody
Product Type : polyclonal Ab Antibody
Immunogen Species : Homo sapiens (Human)
UniProt ID : Q8NFT8
Immunogen : Peptide sequence from Human Delta and Notch-like epidermal growth factor-related receptor protein (150-168AA)
Raised in : Rabbit
Species Reactivity : Human
Tested Applications : ELISA
Background : Activator of the NOTCH1 pathway. May mediate neuron-glia interaction during astrocytogenesis (By similarity).
Clonality : polyclonal Ab
Isotype : IgG
Purification Method : Antigen Affinity Purified
Conj µgate : HRP
Buffer : Preservative : 0.03% Proclin 300
Constituents : 50% Glycerol, 0.01M PBS, pH 7.4
Form : Liquid
Stroage : Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
Target Names : DNER
Research Areas : Neuroscience; Stem cells

Volume : 50 µL
Clone Number :
Aliases : bet antibody; Brain EGF repeat-containing transmembrane protein antibody; Bret antibody; Delta and Notch-like epidermal growth factor-related receptor antibody; Delta notch like EGF repeat containing transmembrane antibody; Delta/notch like EGF repeat containing antibody; Delta/notch-like EGF-related receptor antibody; Dner antibody; DNER_HUMAN antibody; PRO299 antibody; Transmembrane protein Bet antibody; UNQ26 antibody
Product Type : polyclonal Ab Antibody
Immunogen Species : Homo sapiens (Human)
UniProt ID : Q8NFT8
Immunogen : Peptide sequence from Human Delta and Notch-like epidermal growth factor-related receptor protein (150-168AA)
Raised in : Rabbit
Species Reactivity : Human
Tested Applications :
Background : Activator of the NOTCH1 pathway. May mediate neuron-glia interaction during astrocytogenesis (By similarity).
Clonality : polyclonal Ab
Isotype : IgG
Purification Method : Antigen Affinity Purified
Conj µgate : FITC
Buffer : Preservative : 0.03% Proclin 300
Constituents : 50% Glycerol, 0.01M PBS, pH 7.4
Form : Liquid
Stroage : Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
Target Names : DNER
Research Areas : Neuroscience; Stem cells

Volume : 50 µL
Clone Number :
Aliases : bet antibody; Brain EGF repeat-containing transmembrane protein antibody; Bret antibody; Delta and Notch-like epidermal growth factor-related receptor antibody; Delta notch like EGF repeat containing transmembrane antibody; Delta/notch like EGF repeat containing antibody; Delta/notch-like EGF-related receptor antibody; Dner antibody; DNER_HUMAN antibody; PRO299 antibody; Transmembrane protein Bet antibody; UNQ26 antibody
Product Type : polyclonal Ab Antibody
Immunogen Species : Homo sapiens (Human)
UniProt ID : Q8NFT8
Immunogen : Peptide sequence from Human Delta and Notch-like epidermal growth factor-related receptor protein (150-168AA)
Raised in : Rabbit
Species Reactivity : Human
Tested Applications : ELISA
Background : Activator of the NOTCH1 pathway. May mediate neuron-glia interaction during astrocytogenesis (By similarity).
Clonality : polyclonal Ab
Isotype : IgG
Purification Method : Antigen Affinity Purified
Conj µgate : Biotin
Buffer : Preservative : 0.03% Proclin 300
Constituents : 50% Glycerol, 0.01M PBS, pH 7.4
Form : Liquid
Stroage : Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
Target Names : DNER
Research Areas : Neuroscience; Stem cells

Volume : 100 µL
Host : Rabbit
Clonality : polyclonal Ab
Isotype : IgG
GeneName : DNER
GeneID : 92737
Uniprot : Q8NFT8
Specificity : DNER Antibody detects endogenous levels of total DNER.
Immunogen : A syntheVolumed peptide derived from human DNER, corresponding to a region within the internal amino acids.
Storage : Rabbit IgG in phosphate buffered saline , pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol.Store at -20 °C.Stable for 12 months from date of receipt.
Reactivity : Human,Mouse,Rat
Prediction : Pig,Bovine,Horse,Sheep,Rabbit,Dog
Application : WB,IHC,IF/ICC,ELISA(peptide)
Dilution : WB 1 : 1000-3000, IHC 1 : 200, IF/ICC 1 : 100-1 : 500, ELISA(peptide) 1 : 20000-1 : 40000
Conj µgate : Unconj µgated
RRID : AB_2840760
An Introduction to Blocking Peptides : A superior strategy for validation of antibody binding is the use of blocking peptides. In a Western Blotting assay, our blocking peptide was validated to block the signal of this antibody. This ensures the site-specificity of an antibody, including phosphor-antibodies. In the case of the phosphor- antibodies, the antibodies can and will only recognize the phosphorylated target protein at the corresponding site, not the non-phosphorylated target protein or target protein phosphorylated at a different site.
Cat# Blocking Peptide : DF10181-BP
Des# Blocking Peptide : DNER Blocking peptide
Blocking Peptide Price : $549 CAD

Volume : 50 µg
Protein Type : Target proteins
Product Grade : For Research Use.
Tag : C-6His
Species : Mouse
Expressed In : Human Cells
Note : Usually in stock. Smaller quantities and volume discounts are available. For further information, please contact us.

Volume : 50 µL
Clone Number :
Aliases : DNASE2B antibody; DLADDeoxyribonuclease-2-beta antibody; EC 3.1.22.1 antibody; DNase II-like acid DNase antibody; DNase2-like acid DNase antibody; Deoxyribonuclease II beta antibody; DNase II beta antibody; Endonuclease DLAD antibody
Product Type : polyclonal Ab Antibody
Immunogen Species : Homo sapiens (Human)
UniProt ID : Q8WZ79
Immunogen : Recombinant Human Deoxyribonuclease-2-beta protein (68-281AA)
Raised in : Rabbit
Species Reactivity : Human
Tested Applications : ELISA
Background : Hydrolyzes DNA under acidic conditions. Does not require divalent cations for activity. Participates in the degradation of nuclear DNA during lens cell differentiation.
Clonality : polyclonal Ab
Isotype : IgG
Purification Method : >95%, Protein G purified
Conj µgate : HRP
Buffer : Preservative : 0.03% Proclin 300
Constituents : 50% Glycerol, 0.01M PBS, pH 7.4
Form : Liquid
Stroage : Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
Target Names : DNASE2B
Research Areas : Epigenetics and Nuclear Signaling; Neuroscience

Volume : 50 µL
Clone Number :
Aliases : DNASE2B antibody; DLADDeoxyribonuclease-2-beta antibody; EC 3.1.22.1 antibody; DNase II-like acid DNase antibody; DNase2-like acid DNase antibody; Deoxyribonuclease II beta antibody; DNase II beta antibody; Endonuclease DLAD antibody
Product Type : polyclonal Ab Antibody
Immunogen Species : Homo sapiens (Human)
UniProt ID : Q8WZ79
Immunogen : Recombinant Human Deoxyribonuclease-2-beta protein (68-281AA)
Raised in : Rabbit
Species Reactivity : Human
Tested Applications :
Background : Hydrolyzes DNA under acidic conditions. Does not require divalent cations for activity. Participates in the degradation of nuclear DNA during lens cell differentiation.
Clonality : polyclonal Ab
Isotype : IgG
Purification Method : >95%, Protein G purified
Conj µgate : FITC
Buffer : Preservative : 0.03% Proclin 300
Constituents : 50% Glycerol, 0.01M PBS, pH 7.4
Form : Liquid
Stroage : Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
Target Names : DNASE2B
Research Areas : Epigenetics and Nuclear Signaling; Neuroscience

Volume : 50 µL
Clone Number :
Aliases : DNASE2B antibody; DLADDeoxyribonuclease-2-beta antibody; EC 3.1.22.1 antibody; DNase II-like acid DNase antibody; DNase2-like acid DNase antibody; Deoxyribonuclease II beta antibody; DNase II beta antibody; Endonuclease DLAD antibody
Product Type : polyclonal Ab Antibody
Immunogen Species : Homo sapiens (Human)
UniProt ID : Q8WZ79
Immunogen : Recombinant Human Deoxyribonuclease-2-beta protein (68-281AA)
Raised in : Rabbit
Species Reactivity : Human
Tested Applications : ELISA
Background : Hydrolyzes DNA under acidic conditions. Does not require divalent cations for activity. Participates in the degradation of nuclear DNA during lens cell differentiation.
Clonality : polyclonal Ab
Isotype : IgG
Purification Method : >95%, Protein G purified
Conj µgate : Biotin
Buffer : Preservative : 0.03% Proclin 300
Constituents : 50% Glycerol, 0.01M PBS, pH 7.4
Form : Liquid
Stroage : Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
Target Names : DNASE2B
Research Areas : Epigenetics and Nuclear Signaling; Neuroscience

Volume : 100 µL
Host : Rabbit
Clonality : polyclonal Ab
Isotype : IgG
GeneName : DNASE2B
GeneID : 58511
Uniprot : Q8WZ79
Specificity : DNASE2B Antibody detects endogenous levels of total DNASE2B.
Immunogen : A syntheVolumed peptide derived from human DNASE2B, corresponding to a region within C-terminal amino acids.
Storage : Rabbit IgG in phosphate buffered saline , pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol.Store at -20 °C.Stable for 12 months from date of receipt.
Reactivity : Human,Rat
Prediction : Pig,Zebrafish,Bovine,Horse,Sheep,Dog
Application : WB
Dilution : WB 1 : 500-1 : 2000
Conj µgate : Unconj µgated
RRID : AB_2845913
An Introduction to Blocking Peptides : A superior strategy for validation of antibody binding is the use of blocking peptides. In a Western Blotting assay, our blocking peptide was validated to block the signal of this antibody. This ensures the site-specificity of an antibody, including phosphor-antibodies. In the case of the phosphor- antibodies, the antibodies can and will only recognize the phosphorylated target protein at the corresponding site, not the non-phosphorylated target protein or target protein phosphorylated at a different site.
Cat# Blocking Peptide : DF12952-BP
Des# Blocking Peptide : DNASE2B Blocking peptide
Blocking Peptide Price : $549 CAD

Volume : 50 µg
Clone Number :
Aliases : Acid DNase antibody; Deoxyribonuclease 2 alpha antibody; Deoxyribonuclease 2 antibody; Deoxyribonuclease II alpha antibody; Deoxyribonuclease II antibody; Deoxyribonuclease II lysosomal antibody; Deoxyribonuclease-2-alpha antibody; Deoxyribonuclease2 antibody; DeoxyribonucleaseII antibody; DNASE 2 antibody; DNASE 2A antibody; DNase II alpha antibody; DNase II lysosomal antibody; DNASE2 antibody; DNASE2A antibody; DNaseII antibody; DNL 2 antibody; DNL antibody; DNL2 antibody; DNS2A_HUMAN antibody; Lysosomal DNase II antibody; R31240 2 antibody; R31240_2 antibody
Product Type : polyclonal Ab Antibody
Immunogen Species : Homo sapiens (Human)
UniProt ID : O00115
Immunogen : Recombinant Human Deoxyribonuclease-2-alpha protein (19-152AA)
Raised in : Rabbit
Species Reactivity : Human
Tested Applications : ELISA
Background : Hydrolyzes DNA under acidic conditions with a preference for double-stranded DNA. Plays a major role in the degradation of nuclear DNA in cell µLar apoptosis during development. Necessary for proper fetal development and for definitive erythropoiesis in fetal liver, where it degrades nuclear DNA expelled from erythroid precursor cells.
Clonality : polyclonal Ab
Isotype : IgG
Purification Method : >95%, Protein G purified
Conj µgate : HRP
Buffer : Preservative : 0.03% Proclin 300
Constituents : 50% Glycerol, 0.01M PBS, pH 7.4
Form : Liquid
Stroage : Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
Target Names : DNASE2
Research Areas : Epigenetics and Nuclear Signaling; Cancer; Cell biology; Metabolism

Volume : 50 µg
Clone Number :
Aliases : Acid DNase antibody; Deoxyribonuclease 2 alpha antibody; Deoxyribonuclease 2 antibody; Deoxyribonuclease II alpha antibody; Deoxyribonuclease II antibody; Deoxyribonuclease II lysosomal antibody; Deoxyribonuclease-2-alpha antibody; Deoxyribonuclease2 antibody; DeoxyribonucleaseII antibody; DNASE 2 antibody; DNASE 2A antibody; DNase II alpha antibody; DNase II lysosomal antibody; DNASE2 antibody; DNASE2A antibody; DNaseII antibody; DNL 2 antibody; DNL antibody; DNL2 antibody; DNS2A_HUMAN antibody; Lysosomal DNase II antibody; R31240 2 antibody; R31240_2 antibody
Product Type : polyclonal Ab Antibody
Immunogen Species : Homo sapiens (Human)
UniProt ID : O00115
Immunogen : Recombinant Human Deoxyribonuclease-2-alpha protein (19-152AA)
Raised in : Rabbit
Species Reactivity : Human
Tested Applications :
Background : Hydrolyzes DNA under acidic conditions with a preference for double-stranded DNA. Plays a major role in the degradation of nuclear DNA in cell µLar apoptosis during development. Necessary for proper fetal development and for definitive erythropoiesis in fetal liver, where it degrades nuclear DNA expelled from erythroid precursor cells.
Clonality : polyclonal Ab
Isotype : IgG
Purification Method : >95%, Protein G purified
Conj µgate : FITC
Buffer : Preservative : 0.03% Proclin 300
Constituents : 50% Glycerol, 0.01M PBS, pH 7.4
Form : Liquid
Stroage : Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
Target Names : DNASE2
Research Areas : Epigenetics and Nuclear Signaling; Cancer; Cell biology; Metabolism

Volume : 50 µg
Clone Number :
Aliases : Acid DNase antibody; Deoxyribonuclease 2 alpha antibody; Deoxyribonuclease 2 antibody; Deoxyribonuclease II alpha antibody; Deoxyribonuclease II antibody; Deoxyribonuclease II lysosomal antibody; Deoxyribonuclease-2-alpha antibody; Deoxyribonuclease2 antibody; DeoxyribonucleaseII antibody; DNASE 2 antibody; DNASE 2A antibody; DNase II alpha antibody; DNase II lysosomal antibody; DNASE2 antibody; DNASE2A antibody; DNaseII antibody; DNL 2 antibody; DNL antibody; DNL2 antibody; DNS2A_HUMAN antibody; Lysosomal DNase II antibody; R31240 2 antibody; R31240_2 antibody
Product Type : polyclonal Ab Antibody
Immunogen Species : Homo sapiens (Human)
UniProt ID : O00115
Immunogen : Recombinant Human Deoxyribonuclease-2-alpha protein (19-152AA)
Raised in : Rabbit
Species Reactivity : Human
Tested Applications : ELISA
Background : Hydrolyzes DNA under acidic conditions with a preference for double-stranded DNA. Plays a major role in the degradation of nuclear DNA in cell µLar apoptosis during development. Necessary for proper fetal development and for definitive erythropoiesis in fetal liver, where it degrades nuclear DNA expelled from erythroid precursor cells.
Clonality : polyclonal Ab
Isotype : IgG
Purification Method : >95%, Protein G purified
Conj µgate : Biotin
Buffer : Preservative : 0.03% Proclin 300
Constituents : 50% Glycerol, 0.01M PBS, pH 7.4
Form : Liquid
Stroage : Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
Target Names : DNASE2
Research Areas : Epigenetics and Nuclear Signaling; Cancer; Cell biology; Metabolism

Volume : 100 µg
Purification : Immunogen affinity purified
Form : liquid
Purity : 95% as determined by SDS-PAGE
Host : Rabbit
Clonality : polyclonal Ab
Clone ID :
Isotype : IgG
Storage : PBS with 0.02% sodium azide and 50% glycerol pH 7.3,-20? for 12 months(Avoid repeated freeze / thaw cycles.)
Background : Hydrolyzes DNA under acidic conditions with a preference for double-stranded DNA. Plays a major role in the degradation of nuclear DNA in cell µLar apoptosis during development. Necessary for proper fetal development and for definitive erythropoiesis in fetal liver, where it degrades nuclear DNA expelled from erythroid precursor cells.
Immunogen : deoxyribonuclease II, lysosomal
Aliases : DNASE2A, DNL2
Observed MW : 32 kDa
Uniprot ID : O00115
Reactivity : Human, Mouse, Rat
Application : ELISA, WB
Recommended dilution : WB : 1 : 500-1 : 2000
Gene ID : 1777
Research Area : Metabolism, Developmental biology