Volume : 50 µg
Clone Number :
Aliases : DCLRE1B antibody; SNM1B5' exonuclease Apollo antibody; EC 3.1.-.- antibody; DNA cross-link repair 1B protein antibody; SNM1 homolog B antibody; SNMIB antibody; hSNM1B antibody
Product Type : polyclonal Ab Antibody
Immunogen Species : Homo sapiens (Human)
UniProt ID : Q9H816
Immunogen : Recombinant Human 5\' exonuclease Apollo protein (345-493AA)
Raised in : Rabbit
Species Reactivity : Human
Tested Applications : ELISA
Background : 5\'-3\' exonuclease that plays a central role in telomere maintenance and protection during S-phase. Participates in the protection of telomeres against non-homologous end-joining (NHEJ)-mediated repair, thereby ensuring that telomeres do not fuse. Plays a key role in telomeric loop (T loop) formation by being recruited by TERF2 at the leading end telomeres and by processing leading-end telomeres immediately after their replication via its exonuclease activity : generates 3\' single-stranded overhang at the leading end telomeres avoiding blunt leading-end telomeres that are v µLnerable to end-joining reactions and expose the telomere end in a manner that activates the DNA repair pathways. Together with TERF2, required to protect telomeres from replicative damage during replication by controlling the amount of DNA topoisomerase (TOP1 TOP2A and TOP2B) needed for telomere replication during fork passage and prevent aberrant telomere topology. Also involved in response to DNA damage : plays a role in response to DNA interstrand cross-links (ICLs) by facilitating double-strand break formation. In case of spindle stress, involved in prophase checkpoint.
Clonality : polyclonal Ab
Isotype : IgG
Purification Method : >95%, Protein G purified
Conj µgate : Biotin
Buffer : Preservative : 0.03% Proclin 300
Constituents : 50% Glycerol, 0.01M PBS, pH 7.4
Form : Liquid
Stroage : Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
Target Names : DCLRE1B
Research Areas : Others

Volume : 100 µL
Host : Rabbit
Clonality : polyclonal Ab
Isotype : IgG
GeneName : DCLRE1B
GeneID : 64858
Uniprot : Q9H816
Specificity : DCLRE1B Antibody detects endogenous levels of total DCLRE1B.
Immunogen : A syntheVolumed peptide derived from human DCLRE1B, corresponding to a region within the internal amino acids.
Storage : Rabbit IgG in phosphate buffered saline , pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol.Store at -20 °C.Stable for 12 months from date of receipt.
Reactivity : Human
Prediction : Pig,Bovine,Horse,Sheep
Application : WB,ELISA(peptide)
Dilution : WB 1 : 1000-3000, ELISA(peptide) 1 : 20000-1 : 40000
Conj µgate : Unconj µgated
RRID : AB_2842640
An Introduction to Blocking Peptides : A superior strategy for validation of antibody binding is the use of blocking peptides. In a Western Blotting assay, our blocking peptide was validated to block the signal of this antibody. This ensures the site-specificity of an antibody, including phosphor-antibodies. In the case of the phosphor- antibodies, the antibodies can and will only recognize the phosphorylated target protein at the corresponding site, not the non-phosphorylated target protein or target protein phosphorylated at a different site.
Cat# Blocking Peptide : DF9444-BP
Des# Blocking Peptide : DCLRE1B Blocking peptide
Blocking Peptide Price : $549 CAD

Volume : 50 µg
Clone Number :
Aliases : coag µLation factor XI antibody; Coag µLation factor XIa light chain antibody; F11 antibody; FA11_HUMAN antibody; FXI antibody; MGC141891 antibody; Plasma thromboplastin antecedent antibody; Platelet coag µLation factor XI antibody; PTA antibody
Product Type : polyclonal Ab Antibody
Immunogen Species : Homo sapiens (Human)
UniProt ID : P03951
Immunogen : Recombinant Human Coag µLation factor XI protein (19-387AA)
Raised in : Rabbit
Species Reactivity : Human
Tested Applications : ELISA, IHC; Recommended dilution : IHC : 1 : 20-1 : 200
Background : Factor XI triggers the middle phase of the intrinsic pathway of blood coag µLation by activating factor IX.
Clonality : polyclonal Ab
Isotype : IgG
Purification Method : >95%, Protein G purified
Conj µgate : Non-conj µgated
Buffer : Preservative : 0.03% Proclin 300
Constituents : 50% Glycerol, 0.01M PBS, PH 7.4
Form : Liquid
Stroage : Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
Target Names : F11
Research Areas : Cardiovasc µLar

Volume : 50 µL
Clone Number :
Aliases : Activated factor Xa heavy chain antibody; Coag µLation factor X antibody; F10 antibody; FA10_HUMAN antibody; FX antibody; FXA antibody; Prothrombinase antibody; Stuart factor antibody; Stuart Prower factor antibody; Stuart-Prower factor antibody
Product Type : polyclonal Ab Antibody
Immunogen Species : Homo sapiens (Human)
UniProt ID : P00742
Immunogen : Fusion protein of Human F10
Raised in : Rabbit
Species Reactivity : Human, Mouse, Rat
Tested Applications : ELISA, WB; ELISA : 1 : 1000-1 : 2000, WB : 1 : 200-1 : 1000
Background : This gene encodes the vitamin K-dependent coag µLation factor X of the blood coag µLation cascade. This factor undergoes m µLtiple processing steps before its preproprotein is converted to a mature two-chain form by the excision of the tripeptide RKR. Two chains of the factor are held together by 1 or more dis µLfide bonds; the light chain contains 2 EGF-like domains, while the heavy chain contains the catalytic domain which is structurally homologous to those of the other hemostatic serine proteases. The mature factor is activated by the cleavage of the activation peptide by factor IXa (in the intrisic pathway), or by factor VIIa (in the extrinsic pathway). The activated factor then converts prothrombin to thrombin in the presence of factor Va, Ca+2, and phospholipid during blood clotting. Mutations of this gene res µLt in factor X deficiency, a hemorrhagic condition of variable severity.
Clonality : polyclonal Ab
Isotype : IgG
Purification Method : Antigen affinity purification
Conj µgate : Non-conj µgated
Buffer : -20°C, pH7.4 PBS, 0.05% NaN3, 40% Glycerol
Form : Liquid
Stroage : Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
Target Names : F10
Research Areas : Cardiovasc µLar

Volume : 96 Test
Species : Universal
Uniprot ID :
Short name : F-TESTO
Alias : F-TESTO
Sensitivity : 9.375pg/ml
Range : 15.625-1000pg/ml
Detection method : Competitive ELISA, Coated with Antigen
Storage_tempeRature : 2-8 °C for 6 months
Research Area : Signal Transduction

Volume : 96 Test
Species : Universal
Uniprot ID :
Short name : F-E3
Alias : F-E3|Free Estriol
Sensitivity : 0.375ng/ml
Range : 0.625-40ng/ml
Detection method : Competitive ELISA, Coated with Antigen
Storage_tempeRature : 2-8 °C for 6 months
Research Area : Signal Transduction

Volume : 50 µg
Clone Number :
Aliases : F antibody; Fusion glycoprotein F0 [Cleaved into : Fusion glycoprotein F2; Fusion glycoprotein F1] antibody
Product Type : polyclonal Ab Antibody
Immunogen Species : Canine distemper virus (strain Onderstepoort) (CDV)
UniProt ID : P12569
Immunogen : Recombinant Canine distemper virus Fusion glycoprotein F0 protein (136-608AA)
Raised in : Rabbit
Species Reactivity : Canine distemper virus
Tested Applications : ELISA
Background : Class I viral fusion protein. Under the current model, the protein has at least 3 conformational states : pre-fusion native state, pre-hairpin intermediate state, and post-fusion hairpin state. During viral and plasma cell membrane fusion, the heptad repeat (HR) regions assume a trimer-of-hairpins structure, positioning the fusion peptide in close proximity to the C-terminal region of the ectodomain. The formation of this structure appears to drive apposition and subsequent fusion of viral and plasma cell membranes. Directs fusion of viral and cell µLar membranes leading to delivery of the nucleocapsid into the cytoplasm. This fusion is pH independent and occurs directly at the outer cell membrane. The trimer of F1-F2 (F protein) probably interacts with H at the virion surface. Upon HN binding to its cell µLar receptor, the hydrophobic fusion peptide is unmasked and interacts with the cell µLar membrane, inducing the fusion between cell and virion membranes. Later in infection, F proteins expressed at the plasma membrane of infected cells co µLd mediate fusion with adjacent cells to form syncytia, a cytopathic effect that co µLd lead to tissue necrosis.
Clonality : polyclonal Ab
Isotype : IgG
Purification Method : >95%, Protein G purified
Conj µgate : HRP
Buffer : Preservative : 0.03% Proclin 300
Constituents : 50% Glycerol, 0.01M PBS, PH 7.4
Form : Liquid
Stroage : Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
Target Names : F
Research Areas : Others

Volume : 50 µg
Clone Number :
Aliases : F antibody; Fusion glycoprotein F0 [Cleaved into : Fusion glycoprotein F2; Fusion glycoprotein F1] antibody
Product Type : polyclonal Ab Antibody
Immunogen Species : Canine distemper virus (strain Onderstepoort) (CDV)
UniProt ID : P12569
Immunogen : Recombinant Canine distemper virus Fusion glycoprotein F0 protein (136-608AA)
Raised in : Rabbit
Species Reactivity : Canine distemper virus
Tested Applications :
Background : Class I viral fusion protein. Under the current model, the protein has at least 3 conformational states : pre-fusion native state, pre-hairpin intermediate state, and post-fusion hairpin state. During viral and plasma cell membrane fusion, the heptad repeat (HR) regions assume a trimer-of-hairpins structure, positioning the fusion peptide in close proximity to the C-terminal region of the ectodomain. The formation of this structure appears to drive apposition and subsequent fusion of viral and plasma cell membranes. Directs fusion of viral and cell µLar membranes leading to delivery of the nucleocapsid into the cytoplasm. This fusion is pH independent and occurs directly at the outer cell membrane. The trimer of F1-F2 (F protein) probably interacts with H at the virion surface. Upon HN binding to its cell µLar receptor, the hydrophobic fusion peptide is unmasked and interacts with the cell µLar membrane, inducing the fusion between cell and virion membranes. Later in infection, F proteins expressed at the plasma membrane of infected cells co µLd mediate fusion with adjacent cells to form syncytia, a cytopathic effect that co µLd lead to tissue necrosis.
Clonality : polyclonal Ab
Isotype : IgG
Purification Method : >95%, Protein G purified
Conj µgate : FITC
Buffer : Preservative : 0.03% Proclin 300
Constituents : 50% Glycerol, 0.01M PBS, PH 7.4
Form : Liquid
Stroage : Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
Target Names : F
Research Areas : Others

Volume : 50 µg
Clone Number :
Aliases : F antibody; Fusion glycoprotein F0 [Cleaved into : Fusion glycoprotein F2; Fusion glycoprotein F1] antibody
Product Type : polyclonal Ab Antibody
Immunogen Species : Canine distemper virus (strain Onderstepoort) (CDV)
UniProt ID : P12569
Immunogen : Recombinant Canine distemper virus Fusion glycoprotein F0 protein (136-608AA)
Raised in : Rabbit
Species Reactivity : Canine distemper virus
Tested Applications : ELISA
Background : Class I viral fusion protein. Under the current model, the protein has at least 3 conformational states : pre-fusion native state, pre-hairpin intermediate state, and post-fusion hairpin state. During viral and plasma cell membrane fusion, the heptad repeat (HR) regions assume a trimer-of-hairpins structure, positioning the fusion peptide in close proximity to the C-terminal region of the ectodomain. The formation of this structure appears to drive apposition and subsequent fusion of viral and plasma cell membranes. Directs fusion of viral and cell µLar membranes leading to delivery of the nucleocapsid into the cytoplasm. This fusion is pH independent and occurs directly at the outer cell membrane. The trimer of F1-F2 (F protein) probably interacts with H at the virion surface. Upon HN binding to its cell µLar receptor, the hydrophobic fusion peptide is unmasked and interacts with the cell µLar membrane, inducing the fusion between cell and virion membranes. Later in infection, F proteins expressed at the plasma membrane of infected cells co µLd mediate fusion with adjacent cells to form syncytia, a cytopathic effect that co µLd lead to tissue necrosis.
Clonality : polyclonal Ab
Isotype : IgG
Purification Method : >95%, Protein G purified
Conj µgate : Biotin
Buffer : Preservative : 0.03% Proclin 300
Constituents : 50% Glycerol, 0.01M PBS, PH 7.4
Form : Liquid
Stroage : Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
Target Names : F
Research Areas : Others

Volume : 50 µg
Clone Number :
Aliases : F antibody; Fusion glycoprotein F0 [Cleaved into : Fusion glycoprotein F2; Fusion glycoprotein F1] antibody
Product Type : polyclonal Ab Antibody
Immunogen Species : Canine distemper virus (strain Onderstepoort) (CDV)
UniProt ID : P12569
Immunogen : Recombinant Canine distemper virus Fusion glycoprotein F0 protein (136-608AA)
Raised in : Rabbit
Species Reactivity : Canine distemper virus
Tested Applications : ELISA
Background : Class I viral fusion protein. Under the current model, the protein has at least 3 conformational states : pre-fusion native state, pre-hairpin intermediate state, and post-fusion hairpin state. During viral and plasma cell membrane fusion, the heptad repeat (HR) regions assume a trimer-of-hairpins structure, positioning the fusion peptide in close proximity to the C-terminal region of the ectodomain. The formation of this structure appears to drive apposition and subsequent fusion of viral and plasma cell membranes. Directs fusion of viral and cell µLar membranes leading to delivery of the nucleocapsid into the cytoplasm. This fusion is pH independent and occurs directly at the outer cell membrane. The trimer of F1-F2 (F protein) probably interacts with H at the virion surface. Upon HN binding to its cell µLar receptor, the hydrophobic fusion peptide is unmasked and interacts with the cell µLar membrane, inducing the fusion between cell and virion membranes. Later in infection, F proteins expressed at the plasma membrane of infected cells co µLd mediate fusion with adjacent cells to form syncytia, a cytopathic effect that co µLd lead to tissue necrosis.
Clonality : polyclonal Ab
Isotype : IgG
Purification Method : >95%, Protein G purified
Conj µgate : Non-conj µgated
Buffer : Preservative : 0.03% Proclin 300
Constituents : 50% Glycerol, 0.01M PBS, PH 7.4
Form : Liquid
Stroage : Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
Target Names : F
Research Areas : Others

Volume : 50 µg
Protein Type : Other proteins
Product Grade : For Research Use.
Tag : None
Species : Human
Expressed In : E.coli
Note : Usually in stock. Smaller quantities and volume discounts are available. For further information, please contact us.

Volume : 100 µg
Purification : Immunogen affinity purified
Form : liquid
Purity : 95% as determined by SDS-PAGE
Host : Rabbit
Clonality : polyclonal Ab
Clone ID :
Isotype : IgG
Storage : PBS with 0.02% sodium azide and 50% glycerol pH 7.3,-20? for 12 months(Avoid repeated freeze / thaw cycles.)
Background :
Immunogen : ezrin
Aliases : CVIL, CVL, HEL-S-105, VIL2
Observed MW : 90kDa
Uniprot ID : P15311
Reactivity : Human, Mouse, Rat
Application : ELISA, WB, IHC
Recommended dilution : WB : 1 : 500 - 1 : 2000; IHC : 1 : 50 - 1 : 200
Gene ID : 7430
Research Area : Immunology

Volume : 50 µg
Clone Number :
Aliases : Villin 2 ezrin antibody; CVIL antibody; CVL antibody; Cytovillin 2 antibody; Cytovillin antibody; DKFZp762H157 antibody; Epididymis secretory protein Li 105 antibody; EZR antibody; EZRI_HUMAN antibody; Ezrin antibody; FLJ26216 antibody; HEL S 105 antibody; MGC1584 antibody; p81 antibody; VIL 2 antibody; VIL2 antibody; Villin 2 (ezrin) antibody; Villin 2 antibody; Villin-2 antibody; Villin2 antibody
Product Type : polyclonal Ab Antibody
Immunogen Species : Homo sapiens (Human)
UniProt ID : P15311
Immunogen : Recombinant Human Ezrin protein (1-251AA)
Raised in : Rabbit
Species Reactivity : Human
Tested Applications : ELISA
Background : Probably involved in connections of major cytoskeletal structures to the plasma membrane. In epithelial cells, required for the formation of microvilli and membrane ruffles on the apical pole. Along with PLEKHG6, required for normal macropinocytosis.
Clonality : polyclonal Ab
Isotype : IgG
Purification Method : >95%, Protein G purified
Conj µgate : HRP
Buffer : Preservative : 0.03% Proclin 300
Constituents : 50% Glycerol, 0.01M PBS, PH 7.4
Form : Liquid
Stroage : Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
Target Names : EZR
Research Areas : Cancer; Signal transduction

Volume : 50 µg
Clone Number :
Aliases : Villin 2 ezrin antibody; CVIL antibody; CVL antibody; Cytovillin 2 antibody; Cytovillin antibody; DKFZp762H157 antibody; Epididymis secretory protein Li 105 antibody; EZR antibody; EZRI_HUMAN antibody; Ezrin antibody; FLJ26216 antibody; HEL S 105 antibody; MGC1584 antibody; p81 antibody; VIL 2 antibody; VIL2 antibody; Villin 2 (ezrin) antibody; Villin 2 antibody; Villin-2 antibody; Villin2 antibody
Product Type : polyclonal Ab Antibody
Immunogen Species : Homo sapiens (Human)
UniProt ID : P15311
Immunogen : Recombinant Human Ezrin protein (1-251AA)
Raised in : Rabbit
Species Reactivity : Human
Tested Applications :
Background : Probably involved in connections of major cytoskeletal structures to the plasma membrane. In epithelial cells, required for the formation of microvilli and membrane ruffles on the apical pole. Along with PLEKHG6, required for normal macropinocytosis.
Clonality : polyclonal Ab
Isotype : IgG
Purification Method : >95%, Protein G purified
Conj µgate : FITC
Buffer : Preservative : 0.03% Proclin 300
Constituents : 50% Glycerol, 0.01M PBS, PH 7.4
Form : Liquid
Stroage : Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
Target Names : EZR
Research Areas : Cancer; Signal transduction

Volume : 50 µg
Clone Number :
Aliases : Villin 2 ezrin antibody; CVIL antibody; CVL antibody; Cytovillin 2 antibody; Cytovillin antibody; DKFZp762H157 antibody; Epididymis secretory protein Li 105 antibody; EZR antibody; EZRI_HUMAN antibody; Ezrin antibody; FLJ26216 antibody; HEL S 105 antibody; MGC1584 antibody; p81 antibody; VIL 2 antibody; VIL2 antibody; Villin 2 (ezrin) antibody; Villin 2 antibody; Villin-2 antibody; Villin2 antibody
Product Type : polyclonal Ab Antibody
Immunogen Species : Homo sapiens (Human)
UniProt ID : P15311
Immunogen : Recombinant Human Ezrin protein (1-251AA)
Raised in : Rabbit
Species Reactivity : Human
Tested Applications : ELISA
Background : Probably involved in connections of major cytoskeletal structures to the plasma membrane. In epithelial cells, required for the formation of microvilli and membrane ruffles on the apical pole. Along with PLEKHG6, required for normal macropinocytosis.
Clonality : polyclonal Ab
Isotype : IgG
Purification Method : >95%, Protein G purified
Conj µgate : Biotin
Buffer : Preservative : 0.03% Proclin 300
Constituents : 50% Glycerol, 0.01M PBS, PH 7.4
Form : Liquid
Stroage : Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
Target Names : EZR
Research Areas : Cancer; Signal transduction

Volume : 50 µg
Clone Number :
Aliases : Villin 2 ezrin antibody; CVIL antibody; CVL antibody; Cytovillin 2 antibody; Cytovillin antibody; DKFZp762H157 antibody; Epididymis secretory protein Li 105 antibody; EZR antibody; EZRI_HUMAN antibody; Ezrin antibody; FLJ26216 antibody; HEL S 105 antibody; MGC1584 antibody; p81 antibody; VIL 2 antibody; VIL2 antibody; Villin 2 (ezrin) antibody; Villin 2 antibody; Villin-2 antibody; Villin2 antibody
Product Type : polyclonal Ab Antibody
Immunogen Species : Homo sapiens (Human)
UniProt ID : P15311
Immunogen : SyntheVolumed peptide derived from Human Ezrin around the non-phosphorylation site of T566.
Raised in : Rabbit
Species Reactivity : Human, Mouse, Rat
Tested Applications : WB, ELISA; WB : 1 : 500-1 : 2000, ELISA : 1 : 20000
Background :
Clonality : polyclonal Ab
Isotype : IgG
Purification Method : The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
Conj µgate : Non-conj µgated
Buffer : Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.
Form : Liquid
Stroage : Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
Target Names : EZR
Research Areas : Cancer;Signal transduction

Volume : 100 µL
Clone Number :
Aliases : Villin 2 ezrin antibody; CVIL antibody; CVL antibody; Cytovillin 2 antibody; Cytovillin antibody; DKFZp762H157 antibody; Epididymis secretory protein Li 105 antibody; EZR antibody; EZRI_HUMAN antibody; Ezrin antibody; FLJ26216 antibody; HEL S 105 antibody; MGC1584 antibody; p81 antibody; VIL 2 antibody; VIL2 antibody; Villin 2 (ezrin) antibody; Villin 2 antibody; Villin-2 antibody; Villin2 antibody
Product Type : polyclonal Ab Antibody
Immunogen Species : Homo sapiens (Human)
UniProt ID : P15311
Immunogen : SyntheVolumed non-phosphopeptide derived from Human Ezrin around the phosphorylation site of tyrosine 478 (P-V-Y(p)-E-P).
Raised in : Rabbit
Species Reactivity : Human, Mouse
Tested Applications : ELISA, WB; WB : 1 : 500-1 : 3000
Background : Probably involved in connections of major cytoskeletal structures to the plasma membrane. In epithelial cells, required for the formation of microvilli and membrane ruffles on the apical pole. Along with PLEKHG6, required for normal macropinocytosis.

Go µLd K.L., EMBO J. 8 : 4133-4142(1989).
Turunen O., J. Biol. Chem. 264 : 16727-16732(1989).
Mungall A.J., Nature 425 : 805-811(2003).
Clonality : polyclonal Ab
Isotype : IgG
Purification Method : The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
Conj µgate : Non-conj µgated
Buffer : Rabbit IgG in phosphate buffered saline (without Mg2+ and Ca2+), pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol.
Form : liquid
Stroage : Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
Target Names : EZR
Research Areas : Cancer;Signal transduction

Volume : 100 µL
Clone Number :
Aliases : Villin 2 ezrin antibody; CVIL antibody; CVL antibody; Cytovillin 2 antibody; Cytovillin antibody; DKFZp762H157 antibody; Epididymis secretory protein Li 105 antibody; EZR antibody; EZRI_HUMAN antibody; Ezrin antibody; FLJ26216 antibody; HEL S 105 antibody; MGC1584 antibody; p81 antibody; VIL 2 antibody; VIL2 antibody; Villin 2 (ezrin) antibody; Villin 2 antibody; Villin-2 antibody; Villin2 antibody
Product Type : polyclonal Ab Antibody
Immunogen Species : Homo sapiens (Human)
UniProt ID : P15311
Immunogen : Peptide sequence around aa.351~355 (Q-D-Y-E-E) derived from Human EZRIN.
Raised in : Rabbit
Species Reactivity : Human, Mouse
Tested Applications : ELISA, WB; WB : 1 : 500-1 : 1000
Background :
Probably involved in connections of major cytoskeletal structures to the plasma membrane. In epithelial cells, required for the formation of microvilli and membrane ruffles on the apical pole. Along with PLEKHG6, required for normal macropinocytosis.

Zhao H, et al. (2004) Proc Natl Acad Sci U S A101 (25) : 9485-90.
Wang Q, et al. (2003) J Biol Chem 278(48) : 47731-43.
Gautreau A, et al. (1999) Proc Natl Acad Sci U S A : 96(13) : 7300-5.
Crepaldi T, et al. (1997) J Cell Biol : 28; 138(2) : 423-34.
Clonality : polyclonal Ab
Isotype : IgG
Purification Method : Antibodies were produced by immunizing rabbits with synthetic peptide and KLH conj µgates. Antibodies were purified by affinity-chromatography using epitope-specific peptide.
Conj µgate : Non-conj µgated
Buffer : Supplied at 1.0mg/mL in phosphate buffered saline (without Mg2+ and Ca2+), pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol.
Form : liquid
Stroage : Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
Target Names : EZR
Research Areas : Cancer;Signal transduction

Volume : 100 µg
Purification : Immunogen affinity purified
Form : liquid
Purity : 95% as determined by SDS-PAGE
Host : Rabbit
Clonality : polyclonal Ab
Clone ID :
Isotype : IgG
Storage : PBS with 0.02% sodium azide and 50% glycerol pH 7.3,-20? for 12 months(Avoid repeated freeze / thaw cycles.)
Background : Polycomb group(PcG) protein. Catalytic subunit of the PRC2/EED-EZH2 complex, which methylates 'Lys-9'(H3K9me) and 'Lys-27'(H3K27me) of histone H3, leading to transcriptional repression of the affected target gene. Able to mono-, di-and trimethylate 'Lys-27' of histone H3 to form H3K27me1 H3K27me2 and H3K27me3, respectively. Compared to EZH2-containing complexes, it is more abundant in embryonic stem cells and plays a major role in forming H3K27me3, which is required for embryonic stem cell identity and proper differentiation. The PRC2/EED-EZH2 complex may also serve as a recruiting platform for DNA methyltransferases, thereby linking two epigenetic repression systems. Genes repressed by the PRC2/EED-EZH2 complex include HOXC8, HOXA9, MYT1 CDKN2A and retinoic acid target genes. EZH2 can also methylate non-histone proteins such as the transcription factor GATA4 and the nuclear receptor RORA. Reg µLates the circadian clock via histone methylation at the promoter of the circadian genes. Essential for the CRY1/2-mediated repression of the transcriptional activation of PER1/2 by the CLOCK-ARNTL/BMAL1 heterodimer; involved in the di and trimethylation of 'Lys-27' of histone H3 on PER1/2 promoters which is necessary for the CRY1/2 proteins to inhibit transcription.
Immunogen : enhancer of zeste homolog 2(Drosophila)
Aliases : Enhancer of zeste homolog 2, ENX 1 EZH1 EZH2, KMT6, Lysine N methyltransferase 6
Observed MW : 90-102 kDa
Uniprot ID : Q15910
Reactivity : Human, Mouse, Rat
Application : ELISA, WB, IP, IF
Recommended dilution : WB : 1 : 1000-1 : 4000; IP : 1 : 500-1 : 3000; IF : 1 : 20-1 : 200
Gene ID : 2146
Research Area : Epigenetics, Metabolism

Volume : 50 µg
Clone Number :
Aliases : Enhancer of zeste homolog 1 (Drosophila) antibody; Enhancer of zeste homolog 1 antibody; ENX-2 antibody; ENX2 antibody; Ezh1 antibody; EZH1_HUMAN antibody; Histone-lysine N-methyltransferase EZH1 antibody
Product Type : polyclonal Ab Antibody
Immunogen Species : Homo sapiens (Human)
UniProt ID : Q92800
Immunogen : Recombinant Human Histone-lysine N-methyltransferase EZH1 protein (160-280AA)
Raised in : Rabbit
Species Reactivity : Human
Tested Applications : ELISA
Background : Polycomb group (PcG) protein. Catalytic subunit of the PRC2/EED-EZH1 complex, which methylates \\\'Lys-27\\\' of histone H3, leading to transcriptional repression of the affected target gene. Able to mono-, di- and trimethylate \\\'Lys-27\\\' of histone H3 to form H3K27me1 H3K27me2 and H3K27me3, respectively. Required for embryonic stem cell derivation and self-renewal, s µggesting that it is involved in safeguarding embryonic stem cell identity. Compared to EZH2-containing complexes, it is less abundant in embryonic stem cells, has weak methyltransferase activity and plays a less critical role in forming H3K27me3, which is required for embryonic stem cell identity and proper differentiation.
Clonality : polyclonal Ab
Isotype : IgG
Purification Method : >95%, Protein G purified
Conj µgate : HRP
Buffer : Preservative : 0.03% Proclin 300
Constituents : 50% Glycerol, 0.01M PBS, PH 7.4
Form : Liquid
Stroage : Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
Target Names : EZH1
Research Areas : Epigenetics and Nuclear Signaling

Volume : 50 µg
Clone Number :
Aliases : Enhancer of zeste homolog 1 (Drosophila) antibody; Enhancer of zeste homolog 1 antibody; ENX-2 antibody; ENX2 antibody; Ezh1 antibody; EZH1_HUMAN antibody; Histone-lysine N-methyltransferase EZH1 antibody
Product Type : polyclonal Ab Antibody
Immunogen Species : Homo sapiens (Human)
UniProt ID : Q92800
Immunogen : Recombinant Human Histone-lysine N-methyltransferase EZH1 protein (160-280AA)
Raised in : Rabbit
Species Reactivity : Human
Tested Applications :
Background : Polycomb group (PcG) protein. Catalytic subunit of the PRC2/EED-EZH1 complex, which methylates \\\'Lys-27\\\' of histone H3, leading to transcriptional repression of the affected target gene. Able to mono-, di- and trimethylate \\\'Lys-27\\\' of histone H3 to form H3K27me1 H3K27me2 and H3K27me3, respectively. Required for embryonic stem cell derivation and self-renewal, s µggesting that it is involved in safeguarding embryonic stem cell identity. Compared to EZH2-containing complexes, it is less abundant in embryonic stem cells, has weak methyltransferase activity and plays a less critical role in forming H3K27me3, which is required for embryonic stem cell identity and proper differentiation.
Clonality : polyclonal Ab
Isotype : IgG
Purification Method : >95%, Protein G purified
Conj µgate : FITC
Buffer : Preservative : 0.03% Proclin 300
Constituents : 50% Glycerol, 0.01M PBS, PH 7.4
Form : Liquid
Stroage : Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
Target Names : EZH1
Research Areas : Epigenetics and Nuclear Signaling

Volume : 50 µg
Clone Number :
Aliases : Enhancer of zeste homolog 1 (Drosophila) antibody; Enhancer of zeste homolog 1 antibody; ENX-2 antibody; ENX2 antibody; Ezh1 antibody; EZH1_HUMAN antibody; Histone-lysine N-methyltransferase EZH1 antibody
Product Type : polyclonal Ab Antibody
Immunogen Species : Homo sapiens (Human)
UniProt ID : Q92800
Immunogen : Recombinant Human Histone-lysine N-methyltransferase EZH1 protein (160-280AA)
Raised in : Rabbit
Species Reactivity : Human
Tested Applications : ELISA
Background : Polycomb group (PcG) protein. Catalytic subunit of the PRC2/EED-EZH1 complex, which methylates \\\'Lys-27\\\' of histone H3, leading to transcriptional repression of the affected target gene. Able to mono-, di- and trimethylate \\\'Lys-27\\\' of histone H3 to form H3K27me1 H3K27me2 and H3K27me3, respectively. Required for embryonic stem cell derivation and self-renewal, s µggesting that it is involved in safeguarding embryonic stem cell identity. Compared to EZH2-containing complexes, it is less abundant in embryonic stem cells, has weak methyltransferase activity and plays a less critical role in forming H3K27me3, which is required for embryonic stem cell identity and proper differentiation.
Clonality : polyclonal Ab
Isotype : IgG
Purification Method : >95%, Protein G purified
Conj µgate : Biotin
Buffer : Preservative : 0.03% Proclin 300
Constituents : 50% Glycerol, 0.01M PBS, PH 7.4
Form : Liquid
Stroage : Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
Target Names : EZH1
Research Areas : Epigenetics and Nuclear Signaling

Volume : 100 µL
Host : Rabbit
Clonality : polyclonal Ab
Isotype : IgG
GeneName : EZH1
GeneID : 2145
Uniprot : Q92800
Specificity : EZH1 Antibody detects endogenous levels of total EZH1.
Immunogen : A syntheVolumed peptide derived from human EZH1 corresponding to a region within the internal amino acids.
Storage : Rabbit IgG in phosphate buffered saline , pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol.Store at -20 °C.Stable for 12 months from date of receipt.
Reactivity : Human,Mouse,Rat
Prediction : Pig,Bovine,Horse,Sheep,Dog
Application : WB,IHC,IF/ICC,ELISA(peptide)
Dilution : WB 1 : 500-1 : 2000, IHC 1 : 50-1 : 200, IF/ICC 1 : 100-1 : 500, ELISA(peptide) 1 : 20000-1 : 40000
Conj µgate : Unconj µgated
RRID : AB_2837735
An Introduction to Blocking Peptides : A superior strategy for validation of antibody binding is the use of blocking peptides. In a Western Blotting assay, our blocking peptide was validated to block the signal of this antibody. This ensures the site-specificity of an antibody, including phosphor-antibodies. In the case of the phosphor- antibodies, the antibodies can and will only recognize the phosphorylated target protein at the corresponding site, not the non-phosphorylated target protein or target protein phosphorylated at a different site.
Cat# Blocking Peptide : AF5249-BP
Des# Blocking Peptide : EZH1 Blocking peptide
Blocking Peptide Price : $549 CAD

Volume : 100 µL
Host : Mouse
Clonality : Monoclonal
Isotype : IgG1
GeneName :
GeneID :
Uniprot :
Specificity :
Immunogen :
Storage : Mouse IgG1 in phosphate buffered saline (without Mg2+ and Ca2+), pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol.Store at -20 °C.Stable for 12 months from date of receipt.
Reactivity : All
Prediction :
Application : WB
Dilution : WB 1 : 1000-1 : 10000
Conj µgate : Unconj µgated
RRID : AB_2846200
An Introduction to Blocking Peptides : A superior strategy for validation of antibody binding is the use of blocking peptides. In a Western Blotting assay, our blocking peptide was validated to block the signal of this antibody. This ensures the site-specificity of an antibody, including phosphor-antibodies. In the case of the phosphor- antibodies, the antibodies can and will only recognize the phosphorylated target protein at the corresponding site, not the non-phosphorylated target protein or target protein phosphorylated at a different site.
Cat# Blocking Peptide :
Des# Blocking Peptide :
Blocking Peptide Price : $549 CAD

Volume : 50 µg
Clone Number :
Aliases :
Product Type : Monoclonal Antibody
Immunogen Species :
UniProt ID :
Immunogen : Recombinant Protein
Raised in : Mouse
Species Reactivity : All
Tested Applications : ELISA,WB;Recommended dilution : WB : 1 : 500-1 : 5000
Background :
Clonality : Monoclonal
Isotype : IgG
Purification Method : The antibody was affinity-purified from mouse ascites by affinity-chromatography using specific immunogen.
Conj µgate : Non-conj µgated
Buffer : PBS, pH 7.4, containing 0.02% sodium azide as Preservative and 50% Glycerol.
Form : liquid
Stroage : Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
Target Names : EYFP
Research Areas : Others

Volume : 50 µg
Clone Number :
Aliases : CMD1J antibody; Deafness, autosomal dominant 10 antibody; DFNA 10 antibody; DFNA10 antibody; dJ78N10.1 (eyes absent (Drosophila) homolog 4) antibody; dJ78N10.1 (eyes absent) antibody; EYA 4 antibody; eya4 antibody; EYA4_HUMAN antibody; Eyes absent 4 antibody; Eyes absent homolog 4 (Drosophila) antibody; Eyes absent homolog 4 antibody; HGNC : 3522 antibody; OTTHUMP00000040267 antibody
Product Type : polyclonal Ab Antibody
Immunogen Species : Homo sapiens (Human)
UniProt ID : O95677
Immunogen : Recombinant Human Eyes absent homolog 4 protein (153-224AA)
Raised in : Rabbit
Species Reactivity : Human
Tested Applications : ELISA
Background : Tyrosine phosphatase that specifically dephosphorylates \'Tyr-142\' of histone H2AX (H2AXY142ph). \'Tyr-142\' phosphorylation of histone H2AX plays a central role in DNA repair and acts as a mark that distinguishes between apoptotic and repair responses to genotoxic stress. Promotes efficient DNA repair by dephosphorylating H2AX, promoting the recruitment of DNA repair complexes containing MDC1. Its function as histone phosphatase probably explains its role in transcription reg µLation during organogenesis. May be involved in development of the eye (By similarity).
Clonality : polyclonal Ab
Isotype : IgG
Purification Method : >95%, Protein G purified
Conj µgate : HRP
Buffer : Preservative : 0.03% Proclin 300
Constituents : 50% Glycerol, 0.01M PBS, pH 7.4
Form : Liquid
Stroage : Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
Target Names : EYA4
Research Areas : Epigenetics and Nuclear Signaling; Neuroscience; Cardiovasc µLar

Volume : 50 µg
Clone Number :
Aliases : CMD1J antibody; Deafness, autosomal dominant 10 antibody; DFNA 10 antibody; DFNA10 antibody; dJ78N10.1 (eyes absent (Drosophila) homolog 4) antibody; dJ78N10.1 (eyes absent) antibody; EYA 4 antibody; eya4 antibody; EYA4_HUMAN antibody; Eyes absent 4 antibody; Eyes absent homolog 4 (Drosophila) antibody; Eyes absent homolog 4 antibody; HGNC : 3522 antibody; OTTHUMP00000040267 antibody
Product Type : polyclonal Ab Antibody
Immunogen Species : Homo sapiens (Human)
UniProt ID : O95677
Immunogen : Recombinant Human Eyes absent homolog 4 protein (153-224AA)
Raised in : Rabbit
Species Reactivity : Human
Tested Applications :
Background : Tyrosine phosphatase that specifically dephosphorylates \'Tyr-142\' of histone H2AX (H2AXY142ph). \'Tyr-142\' phosphorylation of histone H2AX plays a central role in DNA repair and acts as a mark that distinguishes between apoptotic and repair responses to genotoxic stress. Promotes efficient DNA repair by dephosphorylating H2AX, promoting the recruitment of DNA repair complexes containing MDC1. Its function as histone phosphatase probably explains its role in transcription reg µLation during organogenesis. May be involved in development of the eye (By similarity).
Clonality : polyclonal Ab
Isotype : IgG
Purification Method : >95%, Protein G purified
Conj µgate : FITC
Buffer : Preservative : 0.03% Proclin 300
Constituents : 50% Glycerol, 0.01M PBS, pH 7.4
Form : Liquid
Stroage : Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
Target Names : EYA4
Research Areas : Epigenetics and Nuclear Signaling; Neuroscience; Cardiovasc µLar

Volume : 50 µg
Clone Number :
Aliases : CMD1J antibody; Deafness, autosomal dominant 10 antibody; DFNA 10 antibody; DFNA10 antibody; dJ78N10.1 (eyes absent (Drosophila) homolog 4) antibody; dJ78N10.1 (eyes absent) antibody; EYA 4 antibody; eya4 antibody; EYA4_HUMAN antibody; Eyes absent 4 antibody; Eyes absent homolog 4 (Drosophila) antibody; Eyes absent homolog 4 antibody; HGNC : 3522 antibody; OTTHUMP00000040267 antibody
Product Type : polyclonal Ab Antibody
Immunogen Species : Homo sapiens (Human)
UniProt ID : O95677
Immunogen : Recombinant Human Eyes absent homolog 4 protein (153-224AA)
Raised in : Rabbit
Species Reactivity : Human
Tested Applications : ELISA
Background : Tyrosine phosphatase that specifically dephosphorylates \'Tyr-142\' of histone H2AX (H2AXY142ph). \'Tyr-142\' phosphorylation of histone H2AX plays a central role in DNA repair and acts as a mark that distinguishes between apoptotic and repair responses to genotoxic stress. Promotes efficient DNA repair by dephosphorylating H2AX, promoting the recruitment of DNA repair complexes containing MDC1. Its function as histone phosphatase probably explains its role in transcription reg µLation during organogenesis. May be involved in development of the eye (By similarity).
Clonality : polyclonal Ab
Isotype : IgG
Purification Method : >95%, Protein G purified
Conj µgate : Biotin
Buffer : Preservative : 0.03% Proclin 300
Constituents : 50% Glycerol, 0.01M PBS, pH 7.4
Form : Liquid
Stroage : Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
Target Names : EYA4
Research Areas : Epigenetics and Nuclear Signaling; Neuroscience; Cardiovasc µLar

Volume : 100 µg
Purification : Immunogen affinity purified
Form : liquid
Purity : 95% as determined by SDS-PAGE
Host : Rabbit
Clonality : polyclonal Ab
Clone ID :
Isotype : IgG
Storage : PBS with 0.02% sodium azide and 50% glycerol pH 7.3,-20? for 12 months(Avoid repeated freeze / thaw cycles.)
Background : Tyrosine phosphatase that specifically dephosphorylates 'Tyr-142' of histone H2AX(H2AXY142ph). 'Tyr-142' phosphorylation of histone H2AX plays a central role in DNA repair and acts as a mark that distinguishes between apoptotic and repair responses to genotoxic stress. Promotes efficient DNA repair by dephosphorylating H2AX, promoting the recruitment of DNA repair complexes containing MDC1. Its function as histone phosphatase probably explains its role in transcription reg µLation during organogenesis. May be involved in development of the eye(By similarity).
Immunogen : eyes absent homolog 4(Drosophila)
Aliases :
Observed MW : 67 kDa
Uniprot ID : O95677
Reactivity : Human, Mouse
Application : ELISA, WB, IF
Recommended dilution : WB : 1 : 500-1 : 2000; IF : 1 : 20-1 : 200
Gene ID : 2070
Research Area : Neuroscience, Cardiovasc µLar, Metabolism, Developmental biology

Volume : 100 µL
Host : Rabbit
Clonality : polyclonal Ab
Isotype : IgG
GeneName : EYA3
GeneID : 2140
Uniprot : Q99504
Specificity : EYA3 Antibody detects endogenous levels of total EYA3.
Immunogen : A syntheVolumed peptide derived from human EYA3, corresponding to a region within the internal amino acids.
Storage : Rabbit IgG in phosphate buffered saline , pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol.Store at -20 °C.Stable for 12 months from date of receipt.
Reactivity : Human,Mouse,Rat
Prediction : Pig,Bovine,Horse,Sheep,Rabbit,Dog
Application : WB
Dilution : WB 1 : 500-1 : 2000
Conj µgate : Unconj µgated
RRID : AB_2845955
An Introduction to Blocking Peptides : A superior strategy for validation of antibody binding is the use of blocking peptides. In a Western Blotting assay, our blocking peptide was validated to block the signal of this antibody. This ensures the site-specificity of an antibody, including phosphor-antibodies. In the case of the phosphor- antibodies, the antibodies can and will only recognize the phosphorylated target protein at the corresponding site, not the non-phosphorylated target protein or target protein phosphorylated at a different site.
Cat# Blocking Peptide : DF12994-BP
Des# Blocking Peptide : EYA3 Blocking peptide
Blocking Peptide Price : $549 CAD

Volume : 50 µg
Clone Number :
Aliases : EAB 1 antibody; EAB1 antibody; EYA 2 antibody; EYA transcriptional coactivator and phosphatase 2 antibody; EYA2 antibody; EYA2_HUMAN antibody; eyes absent 2 homolog (Drosophila) antibody; Eyes absent homolog 2 (Drosophila) antibody; Eyes absent homolog 2 antibody; Translation of this uORF probably lowers the translation efficiency of EYA2 antibody
Product Type : polyclonal Ab Antibody
Immunogen Species : Homo sapiens (Human)
UniProt ID : O00167
Immunogen : Recombinant Human Eyes absent homolog 2 protein (1-514AA)
Raised in : Rabbit
Species Reactivity : Human
Tested Applications : ELISA
Background : Functions both as protein phosphatase and as transcriptional coactivator for SIX1 and probably also for SIX2, SIX4 and SIX5. Tyrosine phosphatase that dephosphorylates \'Tyr-142\' of histone H2AX (H2AXY142ph) and promotes efficient DNA repair via the recruitment of DNA repair complexes containing MDC1. \'Tyr-142\' phosphorylation of histone H2AX plays a central role in DNA repair and acts as a mark that distinguishes between apoptotic and repair responses to genotoxic stress. Its function as histone phosphatase may contribute to its function in transcription reg µLation during organogenesis. Plays an important role in hypaxial muscle development together with SIX1 and DACH2; in this it is functionally redundant with EYA1.
Clonality : polyclonal Ab
Isotype : IgG
Purification Method : >95%, Protein G purified
Conj µgate : HRP
Buffer : Preservative : 0.03% Proclin 300
Constituents : 50% Glycerol, 0.01M PBS, PH 7.4
Form : Liquid
Stroage : Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
Target Names : EYA2
Research Areas : Epigenetics and Nuclear Signaling; Neuroscience; Signal transduction

Volume : 50 µg
Clone Number :
Aliases : EAB 1 antibody; EAB1 antibody; EYA 2 antibody; EYA transcriptional coactivator and phosphatase 2 antibody; EYA2 antibody; EYA2_HUMAN antibody; eyes absent 2 homolog (Drosophila) antibody; Eyes absent homolog 2 (Drosophila) antibody; Eyes absent homolog 2 antibody; Translation of this uORF probably lowers the translation efficiency of EYA2 antibody
Product Type : polyclonal Ab Antibody
Immunogen Species : Homo sapiens (Human)
UniProt ID : O00167
Immunogen : Recombinant Human Eyes absent homolog 2 protein (1-514AA)
Raised in : Rabbit
Species Reactivity : Human
Tested Applications :
Background : Functions both as protein phosphatase and as transcriptional coactivator for SIX1 and probably also for SIX2, SIX4 and SIX5. Tyrosine phosphatase that dephosphorylates \'Tyr-142\' of histone H2AX (H2AXY142ph) and promotes efficient DNA repair via the recruitment of DNA repair complexes containing MDC1. \'Tyr-142\' phosphorylation of histone H2AX plays a central role in DNA repair and acts as a mark that distinguishes between apoptotic and repair responses to genotoxic stress. Its function as histone phosphatase may contribute to its function in transcription reg µLation during organogenesis. Plays an important role in hypaxial muscle development together with SIX1 and DACH2; in this it is functionally redundant with EYA1.
Clonality : polyclonal Ab
Isotype : IgG
Purification Method : >95%, Protein G purified
Conj µgate : FITC
Buffer : Preservative : 0.03% Proclin 300
Constituents : 50% Glycerol, 0.01M PBS, PH 7.4
Form : Liquid
Stroage : Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
Target Names : EYA2
Research Areas : Epigenetics and Nuclear Signaling; Neuroscience; Signal transduction

Volume : 50 µg
Clone Number :
Aliases : EAB 1 antibody; EAB1 antibody; EYA 2 antibody; EYA transcriptional coactivator and phosphatase 2 antibody; EYA2 antibody; EYA2_HUMAN antibody; eyes absent 2 homolog (Drosophila) antibody; Eyes absent homolog 2 (Drosophila) antibody; Eyes absent homolog 2 antibody; Translation of this uORF probably lowers the translation efficiency of EYA2 antibody
Product Type : polyclonal Ab Antibody
Immunogen Species : Homo sapiens (Human)
UniProt ID : O00167
Immunogen : Recombinant Human Eyes absent homolog 2 protein (1-514AA)
Raised in : Rabbit
Species Reactivity : Human
Tested Applications : ELISA
Background : Functions both as protein phosphatase and as transcriptional coactivator for SIX1 and probably also for SIX2, SIX4 and SIX5. Tyrosine phosphatase that dephosphorylates \'Tyr-142\' of histone H2AX (H2AXY142ph) and promotes efficient DNA repair via the recruitment of DNA repair complexes containing MDC1. \'Tyr-142\' phosphorylation of histone H2AX plays a central role in DNA repair and acts as a mark that distinguishes between apoptotic and repair responses to genotoxic stress. Its function as histone phosphatase may contribute to its function in transcription reg µLation during organogenesis. Plays an important role in hypaxial muscle development together with SIX1 and DACH2; in this it is functionally redundant with EYA1.
Clonality : polyclonal Ab
Isotype : IgG
Purification Method : >95%, Protein G purified
Conj µgate : Biotin
Buffer : Preservative : 0.03% Proclin 300
Constituents : 50% Glycerol, 0.01M PBS, PH 7.4
Form : Liquid
Stroage : Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
Target Names : EYA2
Research Areas : Epigenetics and Nuclear Signaling; Neuroscience; Signal transduction

Volume : 100 µL
Host : Rabbit
Clonality : polyclonal Ab
Isotype : IgG
GeneName : EYA2
GeneID : 2139
Uniprot : O00167
Specificity : EYA2 Antibody detects endogenous levels of total EYA2.
Immunogen : A syntheVolumed peptide derived from human EYA2, corresponding to a region within the internal amino acids.
Storage : Rabbit IgG in phosphate buffered saline , pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol.Store at -20 °C.Stable for 12 months from date of receipt.
Reactivity : Human,Rat
Prediction : Pig,Bovine,Horse,Sheep,Rabbit,Dog
Application : WB,IF/ICC,ELISA(peptide)
Dilution : WB 1 : 1000-3000, IF/ICC 1 : 100-1 : 500, ELISA(peptide) 1 : 20000-1 : 40000
Conj µgate : Unconj µgated
RRID : AB_2841326
An Introduction to Blocking Peptides : A superior strategy for validation of antibody binding is the use of blocking peptides. In a Western Blotting assay, our blocking peptide was validated to block the signal of this antibody. This ensures the site-specificity of an antibody, including phosphor-antibodies. In the case of the phosphor- antibodies, the antibodies can and will only recognize the phosphorylated target protein at the corresponding site, not the non-phosphorylated target protein or target protein phosphorylated at a different site.
Cat# Blocking Peptide : DF7909-BP
Des# Blocking Peptide : EYA2 Blocking peptide
Blocking Peptide Price : $549 CAD

Volume : 50 µg
Clone Number :
Aliases :
Product Type : polyclonal Ab Antibody
Immunogen Species : Homo sapiens (Human)
UniProt ID : Q99502/O95677
Immunogen : Synthetic peptide from Human protein at AA range : 271-320
Raised in : Rabbit
Species Reactivity : Human, Mouse
Tested Applications : IHC, ELISA; IHC : 1 : 50-300, ELISA : 1 : 10000-20000
Background :
Clonality : polyclonal Ab
Isotype : IgG
Purification Method : The antibody was affinity-purified from rabbit serum by affinity-chromatography using specific immunogen.
Conj µgate : Non-conj µgated
Buffer : PBS, pH 7.4, containing 0.02% sodium azide as Preservative and 50% Glycerol.
Form : Liquid
Stroage : Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
Target Names : EYA1/EYA4
Research Areas : Epigenetics and Nuclear Signaling;Developmental biology

Volume : 50 µg
Clone Number :
Aliases : BOP antibody; BOR antibody; BOS1 antibody; EYA transcriptional coactivator and phosphatase 1 antibody; Eya1 antibody; EYA1_HUMAN antibody; Eyes absent 1 antibody; Eyes absent 1 homolog antibody; Eyes absent homolog 1 (Drosophila) antibody; Eyes absent homolog 1 antibody; Eyes absent homolog1 antibody; MGC141875 antibody; OFC1 antibody
Product Type : polyclonal Ab Antibody
Immunogen Species : Homo sapiens (Human)
UniProt ID : Q99502
Immunogen : Recombinant Human Eyes absent homolog 1 protein (168-321AA)
Raised in : Rabbit
Species Reactivity : Human
Tested Applications : ELISA
Background : Functions both as protein phosphatase and as transcriptional coactivator for SIX1 and probably also for SIX2, SIX4 and SIX5 (By similarity). Tyrosine phosphatase that dephosphorylates \'Tyr-142\' of histone H2AX (H2AXY142ph) and promotes efficient DNA repair via the recruitment of DNA repair complexes containing MDC1. \'Tyr-142\' phosphorylation of histone H2AX plays a central role in DNA repair and acts as a mark that distinguishes between apoptotic and repair responses to genotoxic stress (PubMed : 19234442). Its function as histone phosphatase may contribute to its function in transcription reg µLation during organogenesis (By similarity). Has also phosphatase activity with proteins phosphorylated on Ser and Thr residues (in vitro) (By similarity). Required for normal embryonic development of the craniofacial and trunk skeleton, kidneys and ears (By similarity). Together with SIX1 it plays an important role in hypaxial muscle development; in this it is functionally redundant with EYA2 (By similarity).
Clonality : polyclonal Ab
Isotype : IgG
Purification Method : >95%, Protein G purified
Conj µgate : HRP
Buffer : Preservative : 0.03% Proclin 300
Constituents : 50% Glycerol, 0.01M PBS, pH 7.4
Form : Liquid
Stroage : Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
Target Names : EYA1
Research Areas : Epigenetics and Nuclear Signaling; Developmental biology

Volume : 50 µg
Clone Number :
Aliases : BOP antibody; BOR antibody; BOS1 antibody; EYA transcriptional coactivator and phosphatase 1 antibody; Eya1 antibody; EYA1_HUMAN antibody; Eyes absent 1 antibody; Eyes absent 1 homolog antibody; Eyes absent homolog 1 (Drosophila) antibody; Eyes absent homolog 1 antibody; Eyes absent homolog1 antibody; MGC141875 antibody; OFC1 antibody
Product Type : polyclonal Ab Antibody
Immunogen Species : Homo sapiens (Human)
UniProt ID : Q99502
Immunogen : Recombinant Human Eyes absent homolog 1 protein (168-321AA)
Raised in : Rabbit
Species Reactivity : Human
Tested Applications :
Background : Functions both as protein phosphatase and as transcriptional coactivator for SIX1 and probably also for SIX2, SIX4 and SIX5 (By similarity). Tyrosine phosphatase that dephosphorylates \'Tyr-142\' of histone H2AX (H2AXY142ph) and promotes efficient DNA repair via the recruitment of DNA repair complexes containing MDC1. \'Tyr-142\' phosphorylation of histone H2AX plays a central role in DNA repair and acts as a mark that distinguishes between apoptotic and repair responses to genotoxic stress (PubMed : 19234442). Its function as histone phosphatase may contribute to its function in transcription reg µLation during organogenesis (By similarity). Has also phosphatase activity with proteins phosphorylated on Ser and Thr residues (in vitro) (By similarity). Required for normal embryonic development of the craniofacial and trunk skeleton, kidneys and ears (By similarity). Together with SIX1 it plays an important role in hypaxial muscle development; in this it is functionally redundant with EYA2 (By similarity).
Clonality : polyclonal Ab
Isotype : IgG
Purification Method : >95%, Protein G purified
Conj µgate : FITC
Buffer : Preservative : 0.03% Proclin 300
Constituents : 50% Glycerol, 0.01M PBS, pH 7.4
Form : Liquid
Stroage : Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
Target Names : EYA1
Research Areas : Epigenetics and Nuclear Signaling; Developmental biology

Volume : 50 µg
Clone Number :
Aliases : BOP antibody; BOR antibody; BOS1 antibody; EYA transcriptional coactivator and phosphatase 1 antibody; Eya1 antibody; EYA1_HUMAN antibody; Eyes absent 1 antibody; Eyes absent 1 homolog antibody; Eyes absent homolog 1 (Drosophila) antibody; Eyes absent homolog 1 antibody; Eyes absent homolog1 antibody; MGC141875 antibody; OFC1 antibody
Product Type : polyclonal Ab Antibody
Immunogen Species : Homo sapiens (Human)
UniProt ID : Q99502
Immunogen : Recombinant Human Eyes absent homolog 1 protein (168-321AA)
Raised in : Rabbit
Species Reactivity : Human
Tested Applications : ELISA
Background : Functions both as protein phosphatase and as transcriptional coactivator for SIX1 and probably also for SIX2, SIX4 and SIX5 (By similarity). Tyrosine phosphatase that dephosphorylates \'Tyr-142\' of histone H2AX (H2AXY142ph) and promotes efficient DNA repair via the recruitment of DNA repair complexes containing MDC1. \'Tyr-142\' phosphorylation of histone H2AX plays a central role in DNA repair and acts as a mark that distinguishes between apoptotic and repair responses to genotoxic stress (PubMed : 19234442). Its function as histone phosphatase may contribute to its function in transcription reg µLation during organogenesis (By similarity). Has also phosphatase activity with proteins phosphorylated on Ser and Thr residues (in vitro) (By similarity). Required for normal embryonic development of the craniofacial and trunk skeleton, kidneys and ears (By similarity). Together with SIX1 it plays an important role in hypaxial muscle development; in this it is functionally redundant with EYA2 (By similarity).
Clonality : polyclonal Ab
Isotype : IgG
Purification Method : >95%, Protein G purified
Conj µgate : Biotin
Buffer : Preservative : 0.03% Proclin 300
Constituents : 50% Glycerol, 0.01M PBS, pH 7.4
Form : Liquid
Stroage : Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
Target Names : EYA1
Research Areas : Epigenetics and Nuclear Signaling; Developmental biology

Volume : 100 µL
Host : Rabbit
Clonality : polyclonal Ab
Isotype : IgG
GeneName : EYA1
GeneID : 2138
Uniprot : Q99502
Specificity : EYA1 Antibody detects endogenous levels of EYA1.
Immunogen : A syntheVolumed peptide derived from human EYA1.
Storage : Rabbit IgG in phosphate buffered saline, pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol. Store at -20 °C. Stable for 12 months from date of receipt.
Reactivity : Human,Mouse
Prediction :
Application : ELISA(peptide)
Dilution : ELISA(peptide) 1 : 20000-1 : 40000
Conj µgate : Unconj µgated
RRID :
An Introduction to Blocking Peptides : A superior strategy for validation of antibody binding is the use of blocking peptides. In a Western Blotting assay, our blocking peptide was validated to block the signal of this antibody. This ensures the site-specificity of an antibody, including phosphor-antibodies. In the case of the phosphor- antibodies, the antibodies can and will only recognize the phosphorylated target protein at the corresponding site, not the non-phosphorylated target protein or target protein phosphorylated at a different site.
Cat# Blocking Peptide : DF14764-BP
Des# Blocking Peptide : EYA1 Blocking peptide
Blocking Peptide Price : $549 CAD

Volume : 50 µg
Clone Number :
Aliases : botv antibody; DKFZp686C2342 antibody; Exostoses (m µLtiple)-like 3 antibody; Exostoses-like 3 antibody; Exostosin-like 3 antibody; EXT-related protein 1 antibody; EXTL1L antibody; EXTL3 antibody; EXTL3_HUMAN antibody; EXTR1 antibody; Glucuronyl-galactosyl-proteoglycan 4-alpha-N-acetylglucosaminyltransferas antibody; Glucuronyl-galactosyl-proteoglycan 4-alpha-N-acetylglucosaminyltransferase antibody; Hereditary m µLtiple exostoses gene isolog antibody; KIAA0519 antibody; M µLtiple exostosis-like protein 3 antibody; Putative tumor suppressor protein EXTL3 antibody; REG antibody; Reg receptor antibody; REGR antibody; RPR antibody
Product Type : polyclonal Ab Antibody
Immunogen Species : Homo sapiens (Human)
UniProt ID : O43909
Immunogen : Recombinant Human Exostosin-like 3 protein (2-245AA)
Raised in : Rabbit
Species Reactivity : Human
Tested Applications : ELISA
Background : Glycosyltransferase which reg µLates the biosynthesis of heparan s µLfate (HS). Important for both skeletal development and hematopoiesis, thro µgh the formation of HS proteoglycans (HSPGs) (PubMed : 28132690, PubMed : 28148688). Required for the function of REG3A in reg µLating keratinocyte proliferation and differentiation (PubMed : 22727489).
Clonality : polyclonal Ab
Isotype : IgG
Purification Method : >95%, Protein G purified
Conj µgate : HRP
Buffer : Preservative : 0.03% Proclin 300
Constituents : 50% Glycerol, 0.01M PBS, PH 7.4
Form : Liquid
Stroage : Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
Target Names : EXTL3
Research Areas : Others

Volume : 50 µg
Clone Number :
Aliases : botv antibody; DKFZp686C2342 antibody; Exostoses (m µLtiple)-like 3 antibody; Exostoses-like 3 antibody; Exostosin-like 3 antibody; EXT-related protein 1 antibody; EXTL1L antibody; EXTL3 antibody; EXTL3_HUMAN antibody; EXTR1 antibody; Glucuronyl-galactosyl-proteoglycan 4-alpha-N-acetylglucosaminyltransferas antibody; Glucuronyl-galactosyl-proteoglycan 4-alpha-N-acetylglucosaminyltransferase antibody; Hereditary m µLtiple exostoses gene isolog antibody; KIAA0519 antibody; M µLtiple exostosis-like protein 3 antibody; Putative tumor suppressor protein EXTL3 antibody; REG antibody; Reg receptor antibody; REGR antibody; RPR antibody
Product Type : polyclonal Ab Antibody
Immunogen Species : Homo sapiens (Human)
UniProt ID : O43909
Immunogen : Recombinant Human Exostosin-like 3 protein (2-245AA)
Raised in : Rabbit
Species Reactivity : Human
Tested Applications :
Background : Glycosyltransferase which reg µLates the biosynthesis of heparan s µLfate (HS). Important for both skeletal development and hematopoiesis, thro µgh the formation of HS proteoglycans (HSPGs) (PubMed : 28132690, PubMed : 28148688). Required for the function of REG3A in reg µLating keratinocyte proliferation and differentiation (PubMed : 22727489).
Clonality : polyclonal Ab
Isotype : IgG
Purification Method : >95%, Protein G purified
Conj µgate : FITC
Buffer : Preservative : 0.03% Proclin 300
Constituents : 50% Glycerol, 0.01M PBS, PH 7.4
Form : Liquid
Stroage : Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
Target Names : EXTL3
Research Areas : Others

Volume : 50 µg
Clone Number :
Aliases : botv antibody; DKFZp686C2342 antibody; Exostoses (m µLtiple)-like 3 antibody; Exostoses-like 3 antibody; Exostosin-like 3 antibody; EXT-related protein 1 antibody; EXTL1L antibody; EXTL3 antibody; EXTL3_HUMAN antibody; EXTR1 antibody; Glucuronyl-galactosyl-proteoglycan 4-alpha-N-acetylglucosaminyltransferas antibody; Glucuronyl-galactosyl-proteoglycan 4-alpha-N-acetylglucosaminyltransferase antibody; Hereditary m µLtiple exostoses gene isolog antibody; KIAA0519 antibody; M µLtiple exostosis-like protein 3 antibody; Putative tumor suppressor protein EXTL3 antibody; REG antibody; Reg receptor antibody; REGR antibody; RPR antibody
Product Type : polyclonal Ab Antibody
Immunogen Species : Homo sapiens (Human)
UniProt ID : O43909
Immunogen : Recombinant Human Exostosin-like 3 protein (2-245AA)
Raised in : Rabbit
Species Reactivity : Human
Tested Applications : ELISA
Background : Glycosyltransferase which reg µLates the biosynthesis of heparan s µLfate (HS). Important for both skeletal development and hematopoiesis, thro µgh the formation of HS proteoglycans (HSPGs) (PubMed : 28132690, PubMed : 28148688). Required for the function of REG3A in reg µLating keratinocyte proliferation and differentiation (PubMed : 22727489).
Clonality : polyclonal Ab
Isotype : IgG
Purification Method : >95%, Protein G purified
Conj µgate : Biotin
Buffer : Preservative : 0.03% Proclin 300
Constituents : 50% Glycerol, 0.01M PBS, PH 7.4
Form : Liquid
Stroage : Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
Target Names : EXTL3
Research Areas : Others

Volume : 100 µL
Host : Rabbit
Clonality : polyclonal Ab
Isotype : IgG
GeneName : EXTL3
GeneID : 2137
Uniprot : O43909
Specificity : EXTL3 Antibody detects endogenous levels of total EXTL3.
Immunogen : A syntheVolumed peptide derived from human EXTL3, corresponding to a region within the internal amino acids.
Storage : Rabbit IgG in phosphate buffered saline , pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol.Store at -20 °C.Stable for 12 months from date of receipt.
Reactivity : Human,Mouse,Rat
Prediction : Pig,Zebrafish,Bovine,Horse,Sheep,Rabbit,Dog,Chicken,Xenopus
Application : WB
Dilution : WB 1 : 500-1 : 2000
Conj µgate : Unconj µgated
RRID : AB_2845954
An Introduction to Blocking Peptides : A superior strategy for validation of antibody binding is the use of blocking peptides. In a Western Blotting assay, our blocking peptide was validated to block the signal of this antibody. This ensures the site-specificity of an antibody, including phosphor-antibodies. In the case of the phosphor- antibodies, the antibodies can and will only recognize the phosphorylated target protein at the corresponding site, not the non-phosphorylated target protein or target protein phosphorylated at a different site.
Cat# Blocking Peptide : DF12993-BP
Des# Blocking Peptide : EXTL3 Blocking peptide
Blocking Peptide Price : $549 CAD

Volume : 100 µL
Host : Rabbit
Clonality : polyclonal Ab
Isotype : IgG
GeneName : EXTL2
GeneID : 2135
Uniprot : Q9UBQ6
Specificity : EXTL2 Antibody detects endogenous levels of EXTL2.
Immunogen : A syntheVolumed peptide derived from human EXTL2.
Storage : Rabbit IgG in phosphate buffered saline, pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol. Store at -20 °C. Stable for 12 months from date of receipt.
Reactivity : Human,Mouse
Prediction :
Application : ELISA(peptide)
Dilution : ELISA(peptide) 1 : 20000-1 : 40000
Conj µgate : Unconj µgated
RRID :
An Introduction to Blocking Peptides : A superior strategy for validation of antibody binding is the use of blocking peptides. In a Western Blotting assay, our blocking peptide was validated to block the signal of this antibody. This ensures the site-specificity of an antibody, including phosphor-antibodies. In the case of the phosphor- antibodies, the antibodies can and will only recognize the phosphorylated target protein at the corresponding site, not the non-phosphorylated target protein or target protein phosphorylated at a different site.
Cat# Blocking Peptide : DF16070-BP
Des# Blocking Peptide : EXTL2 Blocking peptide
Blocking Peptide Price : $549 CAD